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胃药

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They were fed with medicine intragastrically. The earlap inflammation caused by bimethylbenzene, the effect on pain induced glacial acetic-acid, the influence on the penetrability of capillary vellset in the abdominal cacity and the weight of rat cotton-ball granuloma were observed. 2.Acute toxicity test: Twenty mice were fed with the rhinitis capsule solution of most concentration and volume by intragastrically. All the actions and the appearance of major organs were observed in twenty-four hours and one week.

分别灌胃给药,观察该药对小鼠二甲苯性耳壳炎症、冰醋酸致痛作用及冰醋酸致腹腔毛细血管通透性增高和大鼠棉球肉芽肿的影响。2、急性毒性实验:20只小鼠灌胃给以最大浓度和最大剂量鼻炎胶囊溶液,用药24小时和1周后观察动物的一切活动及各主要脏器的外观形态。

The distribution characteristics of primary neurons in skin referral area and gastric mucosa are that spinal ganglions present segmental distribution and superposing with each other,moreover,sympathetic ganglions present diffused distribution and have no segmental distribution,which may be the neural basis of treating visceral pain by intracutaneous- injection drug.

结论胃痛的皮肤牵涉区与胃黏膜初级神经元分布的特点是在脊神经节呈节段性分布且相互重叠,在交感神经节呈弥散性分布,无节段性分布,也相互重叠,这可能是皮内注药治疗内脏痛的神经基础。

Results In vitro ,daphnetin exhibited potent schizontocidal activity comparable to chloroquine at the dose range of 1~10 μmol/L. In vivo ,50 or 100 mg/kg.d -1 ×4 d daphnetin i.g. and 10,50 or 100 mg/kg.d -1 ×4 d dephnetin i.p. showed antimalarial efficacy comparable to CQ 10 mg/kg.d -1 ×4 d i.g. in mice infected with P. berghei ANKA, evaluated by both the reduction rate of parasitemia on D 4 and the average surviving days in 30 days.

结果 体外试验中瑞香素在 1~ 10 μmol L剂量范围内有明显杀灭裂殖体作用,而体内试验中按D4减虫率与感染鼠在 30d内的平均生存天数评价,5 0或 10 0mg kg 。d- 1 × 4d瑞香素灌胃以及 10 ,5 0或 10 0mg kg.d- 1 × 4d瑞香素腹腔注射给药在伯氏鼠疟原虫ANKA株感染鼠中的抗疟作用与 10mg kg 。d- 1 × 4d氯喹灌胃的疗效相似。

A substance containing pepsin,obtained from the stomachs of hogs and calves and used as a digestive aid.

助消化药可由猪胃、牛胃中提炼出的含胃蛋白酶的物质,用以帮助消化

Ethyl acetate extract of sappanwood is dilued with olive oil.use the equivalent dosage of active compound sappanwood 35g, 45g, 55g/kg to intragastric administration;blank control group use 0.2ml/10g olive oil to intragastric administration.

苏木乙酸乙酯提取物用橄榄油稀释,以相当于原药苏木35g、45g、55g/kg的剂量灌胃;空白对照组灌服同体积的橄榄油。连续灌胃8天后处死。

Accord- ing to the observation that the compounds were stable in low pH aqueous solution and their sta- bility decreased when pH increased, and they rapidly decomposed to form α-methylenecyclopen- tanones derivative when pH reached 6 to 7, we postulated that the compounds were unabsorbable in stomack (where pH1-3) and unstable in small intestine (where pH5-8). The decomposed product was indeed inactive.

对Ⅰ类化合物在稀溶液中的稳定性研究表明,低pH时化合物较稳定,随着pH值的升高稳定性逐渐降低,pH6~7时,化合物迅速分解成α-亚甲基环戊酮类化合物,由此而推测Ⅰ类化合物经口给药无效的原因为:它们在强酸性的胃中(pH1-3)呈离子状态,因而不易吸收,经胃的排空运动进入肠道后,随着pH逐渐升高(pH5-8)化合物迅速分解,而分解产物α-亚甲基环戊酮类化合物证明是无效的。

All groups were treated by infusing into stomach while the rat began to be induced the model. The normal group and hepatic fibrosis model group were treated with distilled water 10ml/kg everyday ;The colchicines treatment group were treated with 0.2mg/kg everyday ;the small middle and large dose of extract of Achillea millefolium L .treatment group were treated with extract of Achillea millefolium L .3ml/kg,6ml/kg,12ml/kg respectively everyday.

造模同时灌胃给药,空白对照组及肝纤维化模型组每日给予蒸馏水10ml/;阳性对照组每日给予秋水仙碱0.2 mg/;预防研究低、中、高剂量组分别给予蓍草提取物相当于生药3g/,6g/,12g/灌胃,1次/日。

To study the effecacy of heat clearing and Qi regulating prescriptionfor helicobacter felis gastritis in Balb/c mice,sixty model Balb/c mice were randomly allocated to five groups:three HCQRP groups(in 26.6g/kg,13.3g/kg and 6.65g/kg respectively) and triple therapy control group(with metronidazole,tetracycline and bismuth)and saline control group.

为检验清热理气方(蒲公英60g、黄连10g、黄芩10g、枳壳10g、佛手12g、炙甘草6g)对实验性猫胃螺杆菌胃炎的治疗作用。采用复制Balb/c猫胃螺杆菌胃炎模型,以清热理气方大、中、小剂量(分别为26.6g/kg、13.3g/kg、6.65g/kg)给药,以三联疗法(灭滴灵2.6mg、四环素1.3mg、丽珠得乐1.3mg)为阳性对照组,以生理盐水为阴性对照。

Methods: One hundred and sixty SD rats were randomly divided into four groups (40 in each group), and orally given the medicine with doses of 50, 25, or 12.5 g/kg of crude drug, or with bean oil of 0.5%CMC-Na daily for 26 weeks.

160只SD大鼠,随机分为高、中、低剂量组及空白对照组,雌雄各半,每日灌胃1次,连续给药26周,观察大鼠的一般状况、体重、摄食量和给药13、26周及停药

Methods: One hundred and sixty SD rats were randomly divided into four groups (40 in each group), and orally given the medicine with doses of 50, 25, or 12.5 g/kg of crude drug, or with bean oil of 0.5%CMC-Na daily for 26 weeks.

160只SD大鼠,随机分为高、中、低剂量组及空白对照组,雌雄各半,每日灌胃1次,连续给药26周,观察大鼠的一般状况、体重、摄食量和给药13、26周及停药后4周大鼠的血液学、血液生化学、。。。

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