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Objective: A HPLC-ECD method was established to determine scutellarin in rat bile.

中文摘要:目的:建立大鼠胆汁中灯盏花乙素的高效液相-电化学色谱测定方法,研究灌胃给药灯盏花乙素苷元200 mg·kg-1后,代谢产物在胆汁中的排泄方式。

Methods 24 SD rats were randomly divided into normal group,model group,aminophylline treatment group(35 mg/kg), 8 rats in each group. The bronchial asthma model in rats was built by egg protein sensibilization and longterm inhalation provocation. The rats in treatment group were lavaged each day from the first time of provocation.After 4week treatment, the rats were killed to obtain lung tissue for staining with HE.

24只SD大鼠随机分为正常组、模型组、治疗组,每组8只,除正常组外以卵蛋白致敏并吸入激发法制备大鼠哮喘模型,治疗组、模型组从第1次哮喘激发开始(造模第3周)分别给予氨茶碱、0.9%氯化钠溶液灌胃给药,1次/d,用药4周处死大鼠,取肺组织HE染色,用彩色图像分析仪测量支气管壁面积、支气管平滑肌面积,用ELISA双抗体夹心法测定肺组织MMP9和TIMP1含量。

MethodsTo observe the effects of Xiaoshui powder on promoting extinction of tuberculous pleural fluid of Mus musculus albus with the administration route of lavage,counteracting Chronic hyperplastic inflammation ,and in their weight of thymus gland and spleen of mouse, as well as the level of serumal hemolysin.

方法运用灌胃给药途径观察其对小鼠在促进结核性胸水的消退、抗慢性增生性炎症中的作用及其对小鼠胸腺、脾脏的重量和血清溶血素水平的影响。

RESULTS: Extract of Sonchus oleraceus markedly prolonged the living time of the fasting, hypoxia experimetal mice, the formation time of carotid artery thrombosis, decreased blood viscosity shear rate (compared with control, P.01), prevent myocardial ischemia caused by hypophysin.

结果:苦苣提取物灌胃给药12.5g/kg和6.3g/kg均能明显增加小鼠常压下耐缺氧存活时间,能够延长饥饿小鼠的生存时间。3.2g/kg可明显降低大鼠血液黏度,延长大鼠体内血栓形成时间。

The fun ction of visual conduction and sensory in strabismic amblyopia cat′s eyes partl y was improved following a 12-week period stomach-perfusion of LDP.

结论用左旋多巴对猫斜视性弱视模型灌胃给药12周,能一定程度地改善其弱视眼的传导和感觉功能。

The finding indicates that cisplatin may be adequate to treat stomach cancer orally, while its toxication on kidney should not be neglected.

顺铂微晶口服可以在胃组织中维持较高药浓,对治疗胃癌有进一步研究的意义,但其肾毒性不容忽视。

objective to observe the protection of typha angustifolial l extract against rats cerebral ischemia reperfusion injury. methods cerebral ischemia reperfusion models of rats were used, 40 rats were divided into 4 groups randomly to observe the activity of brain tissue lactic dehydrogenase and superoxide dismutase and content of malondial dehyde.

目的 观察蒲黄提取物对脑缺血再灌注损伤的保护作用;方法采用大鼠脑缺血再灌注模型;取sd大鼠40只,随机分为4组,给药组分别给予蒲黄提取物0.2g/kg,0.4g/kg灌胃15 d;另设对照组及假手术组;观察脑组织乳酸脱氢酶和超氧化物歧化酶活性及丙二醛含量变化。

Methods Boiled and filtered the GHTR decoction, garaged wistar rat with certain dose.Accoding to the method of serum pharmacology, extracted the contained-GBTRserum. Selected several male wistar rats, exposed their main arteries of thorax.

将固本化痰通脉方制成水煎剂,按一定剂量给健康雄性Wistar大鼠灌胃,按照血清药理学实验方法,获取固本化痰通脉方含药血清。

The rats were orally treated with referential ferulaic acid, Rhizoma Chuanxiong extraction and Naodesheng capsule repectively. Blood samples were collected by cutting rats tails. Plasma was separated by centrifugation at 10 000 r·min-1 for 10 min, and two-times methanol in volume was added to deposit proteins. After centrifugation, the upper liquid was transferred to filter. The concentration of ferulaic acid in serum was determined by RP-HPLC.

大鼠分别灌胃给予阿魏酸对照品、川芎药材提取物、复方脑得生片,断尾采血,离心,取血浆适量,加甲醇沉淀蛋白,取上清液过滤,用HPLC分析,以C18为固定相,流动相为甲醇-0.5%醋酸水溶液(30∶70),在320 nm检测阿魏酸血药浓度,3p97软件处理数据。

The first thing that happened was that the grains protected the B - subunit from being broken down in the stomach, thus overcoming one of the regular bugbears of protein - based drugs: that they cannot be given by mouth, because they will be digested.

第一件发生的事情就是谷物阻止了 B 亚单位在胃中被破坏,因此克服了常规的以蛋白质为载体的药物的一个常见问题:它们不能口服给药,因为它们将被消化分解。

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In the United States, chronic alcoholism and hepatitis C are the most common ones.

在美国,慢性酒精中毒,肝炎是最常见的。

If you have any questions, you can contact me anytime.

如果有任何问题,你可以随时联系我。

Very pretty, but the airport looks more fascinating The other party wisecracked.

很漂亮,不过停机坪更迷人。那人俏皮地答道。