肿瘤的

If the antitumour efficacy of these epigenetic drugs is eentually demonstrated, they would not only be added to the current anticancer armamentarium, but they will surely be affordable to the ast majority of cancer patients liing in low and middle income countries, who find the newer anticancer agents prohibitiely expensie.

如果这些表观遗传药物抗肿瘤的作用最终得到证实，他们不仅仅增加了当前抗癌的物质，而且他们可以明确的可以使在发现新的抗肿瘤剂相当昂贵的国家收入在中下等的大量肿瘤患者负担的起。

objective to study the anti-tumor activity and enhancing immune effect of phellinus linteus.methods the anti-tumor activity of phellinus linteus was estimated by the longevity of eac mice,the immune effect of tumorous mice was tested by the experiment of carbon particle expurgation and the il-2 concentration in serum of tumorous mice was determined by elisa.results phellinus linteus can prolong eac mouse's life and can increase the il-2 concentration in serum of tumorous mouse but can't affect the immune effect of tumorous mouse.conclusion chinese hurb phellinus linteus possess some antitumor power for tumor-loaded mice,but further research is needed.

目的 观察桑黄对肿瘤的抑制作用及对机体免疫功能的影响。方法以小鼠艾氏腹水癌的生命延长率评价桑黄的抗肿瘤作用，以炭末廓清实验观察荷瘤小鼠非特异性免疫功能，以elisa法测定荷瘤小鼠血清il-2浓度。结果桑黄对eac荷瘤小鼠的生存时间有延长作用，对荷瘤小鼠血清il-2浓度有提高作用，对荷瘤小鼠非特异性免疫功能无明显影响。结论中药桑黄对荷瘤小鼠具有一定的抗肿瘤能力，作用的强度和作用机制的深度还有待进一步研究。

We study the expression levels of GLUT1 in 16 samples of esophageal cancer and their normal mucosa by reverse transcriptasepolymerase chain reaction and immunohistochemical staining, analyse the correlation between the expression level of GLUT1 mRNA and protein in the tumor cells. Then we study the expression levels of GLUT1 in 55 patients with esophageal cancer by immnohistochemical staining, analyse the relationship between GLUT1 expression and clinical features of the patients.

我们采用逆转录聚合酶链反应和免疫组化染色的方法，研究GLUT1 mRNA及蛋白在16例食管癌病人的肿瘤组织和相应正常食管粘膜的表达水平，同时分析食管癌组织中GLUT1在mRNA水平和蛋白水平表达的相关性；采用免疫组化染色的方法研究55例食管癌病人肿瘤标本的GLUT1表达水平，并分析其与肿瘤的临床特性及预后的关系。

"Learning more about the way a specific type of cancer deelops, and what proteins it produces as it grows, helps us find better ways to treat that cancer," said Dr. Lai, who is a cancer researcher at Mayo Clinic with background as an otolaryngologist."With nasopharyngeal cancer, we think this new enzyme may help sole the puzzle."

"了解更多的有关特定肿瘤发育过程的知识，以及其生长过程中产生的蛋白质，能够帮助我们找到更好的治疗肿瘤的办法，"具有耳鼻喉科医师身份，目前作为肿瘤科研人员工作在Mayo临床中心工作的Lai博士说："对于鼻咽癌，我们认为这种新的酶能够解决这些难题。"

Breast cancer is the fourth leading cause of cancer death for Taiwanese women. X-ray mammography is currently the most effective method for an early diagnosis of the breast cancer. The existence of spicules is one of most important visual signs for breast cancer diagnosis. Spiculation is a stellate distortion caused by the intrusion of breast cancer into surrounding tissue. In general, malignant tumors appear with rough and complex boundaries or contours, whereas benign masses present smooth, round, or oval contours.In this paper, we present a technique to detect the contours of spiculated lesions from the regions of interest in a mammographic image.

中文摘要乳癌是是我国妇癌症死亡主因的第四位，乳癌诊断程序中，乳房X光摄影为临床上医生诊断乳癌的利器，在诊断乳房摄影肿瘤的影像时，可用特徵决定为良性或恶性肿瘤，良性肿瘤通常会呈现圆滑的特徵，而恶性肿瘤则呈现星状或不规则不平滑特徵，这种星状或不规则不平滑特徵组织，称为星状物肿瘤，指的是肿瘤周围的乳腺组织，因星状物往外侵犯的关系造成的变形，星状物的存在是恶性肿瘤判断的依据。

Objective To analyze the CT and MRI manifestations of oral carcinoma,and to evaluate the value of imaging technologies in the diagnosis of oral carcinoma,thus to explore the most reasonable imaging method Methods 46 cases with oral carcinoma,proved by surgery and pathology （2 lip tumors,8 carcinomas of the gingival ridge,5 carcinomas of the buccal mucosa,24 tongue carcinomas,5 carcinomas of the floor of the mouth,2 tumors of the hard palate）,were analysed retrospectively32 cases were examined with CT and 14 cases with MRIImaging presentations were compared with surgery and pathology Results Of the 46 cases with oral carcinoma,22 were ulcerative lesion of infiltrative growth,24 were masslike lesion of extruded trowthOf the 32 cases examined with CT scan,27 were detected,5 were missed,the 4 missed cases were confirmed to be superficial ulcers by surgery and pathologyOf the 10 cases with bone destruction examined with CT scan,8 were manifested,2 were missedAnd of the 14 cases with MRI scan,all 14 were detected Conclusion CT and MRI scan are valuable for diagnosis of oral carcinomasThey can manifest the morphology and size of primary tumor,contiguous structures,bone invasion and cervical lymph node metastasisMRI is the optimal imaging method for superficial ulcerative lesion of infiltratibe growth

徐 锋，罗德红，唐威，欧阳汉，周纯武目的分析口腔癌的CT及MRI表现，评价影像检查在口腔癌诊断中的应用价值，探索合理的影像学检查方法。方法回顾性分析经手术及病理证实的口腔癌46例（唇癌2例，牙龈癌8例，颊黏膜癌5例，舌癌24例，口底癌5例，硬腭癌2例），其中32例行CT扫描，14例行MRI扫描，将影像表现与手术所见及病理结果进行对照分析。结果 46例口腔癌中，呈浸润性生长的溃疡型病变22例，外生性生长的肿物型病变24例。CT扫描32例，明确显示病变27例，遗漏病变5例，其中4例为表浅溃疡型病变。CT扫描病例中，10例有骨质侵犯，CT扫描准确评价8例，遗漏2例。MRI扫描14例，均准确评价肿瘤及其与周围结构的关系。结论 CT、MRI对口腔癌原发肿瘤的形态、大小、周围结构侵犯、颈部淋巴结转移的评价有重要价值。对于较小及呈浸润性生长的表浅溃疡型肿瘤，CT扫描尤其是CT平扫难以准确显示，应首选MRI。

Abstract］ objective to evaluate the distinctive clinical value of magnetic resonance urographymru）in the diagnosis of primary ureteral carcinoma.methods to compare the accuracy of diagnosis of mru with ultrasonography,urography,retrograde ureteropyelography and ct,diagnostic imaging and progress of ureteral carcinoma were analyzed in twenty-four cases from 2000 to 2006,twenty cases had mru examinations.the original preoperative diagnostic reports of various imaging facilities were analyzed on account of the results of operation and pathology.results mru could clearly show the obstructive location of ureter.with regard to the ureteral carcinoma,accuracy of the location diagnosis was 100%.mru was superior to ulstrasonography,kub+ivp,ureteropyelography and ct we used to apply.conclusion comparing with other diagnostic imaging facilities,it has an important value in highly efficient,accurate location,safe,noninvasive and so on with mru,which can be used to show the features of primary ureteral carcinoma and has a wider scope of clinical application.

目的 探讨磁共振水成像技术在原发性输尿管肿瘤中的临床诊断价值。方法分析2000～2006年24例原发性输尿管肿瘤的影像学诊断结果，并基于术中所见和病理报告，将磁共振水成像技术20例）与超声24例）、泌尿系造影24例）、逆行造影15例）、ct(19例）的确诊率相比较。结果 mru能清晰显示输尿管的梗阻部位，定位诊断准确率为100%，梗阻病因确诊率高于b超、泌尿系造影、逆行造影和ct检查。结论与其他影像诊断方法相比较，磁共振水成像在显示原发性输尿管肿瘤特征方面具有效率高、定位准确和安全无创等重要价值，而且有更广泛的临床应用范围。

The microwave scattered signal of breast tumor is simulated by using our FDTD codes and poles of the scatted signal of breast tumor are subsequently extracted by using Pronys method.

本文首先详细介绍了奇点展开法的背景及其原理，接着应用我们开发的时域有限差分仿真程序得到早期乳房肿瘤的微波散射信号，采用Prony极点提取方法对肿瘤的微波散射信号进行肿瘤特征极点的提取。

Statistical data of VEGF grading scores showed that its expression was not significantly related to the size and location of glioma, sex, and age of patients, but closely related to the glioma gradings. The expression of TF was positively correlated with that of VEGF, suggesting that TF might participate in the anigogenesis of gliomas, and provide proper environment for the growth of gliomas through its coagulant effect.

根据VEGF分级计数统计学分析，显示VEGF表达与肿瘤的大小、部位及患者性别、发病年龄等临床因素无显著相关性，而与肿瘤的组织学分级密切相关。3、胶质细胞瘤中TF与VEGF的表达正相关，TF可能参与了肿瘤血管的生成过程，并通过其促凝血活性作用为胶质瘤的生长创造适宜的内环境。

The abnormal expressions are not only involved in the development, but also in the lymph nodes metastasis of non-small cell lung carcinomas.

研究表明''－''，CD44蛋白能介导肿瘤细胞与毛细血管内皮细胞结合，在肿瘤细胞的转移中起着重要的作用，CD44蛋白表达阳性的癌细胞可能获得淋巴细胞的&伪装&，容易进人淋巴结，导致转移；CD44蛋白和基因的异常表达与消化、泌尿和生殖等许多系统肿瘤的发展和淋巴结转移密切相关。

I am accused of being overreligious," she said in her quiet, frank manner,"but that does not prevent me thinking the children very cruel who obstinately commit such suicide.""

客人们在卡罗利娜·埃凯家里，举止就文雅一些，因为卡罗利娜的母亲治家很严厉。

Designed by French fashion house Herm è s, this elegant uniform was manufactured in our home, Hong Kong, and was the first without a hat.

由著名品牌 Herm è s 设计，这件高贵的制服是香港本土制造，是我们第一套不配帽子的制服。