肿瘤的

Here we showed that EMT was inhibited by resveratrol through down-regulating the expression of FOXC2 (forkhead box C2), a critical transcription factor involved in EMT transition.

目前的研究显示上皮-间质转化对多种肿瘤的发展进程具有重要的影响，上皮-间质转化可促近肿瘤细胞的浸润以及肿瘤的转移，在人类以及动物实验中发现上皮-间质转化会导致预后不良。

Result］ Under blood stasis, it can to some extent inhibit the production of primary cancer, the serum IL18 and HGF were reduced in mouse of liver metastasis with cancer, which may intervene the liver metastasis; Shensanqi extract had some definite function on the primary cancer of spleen and liver metastasis of rats with liver metastasis of cancer, the platelet exerted key functions in cancer hyperplasia, infiltration and metastasis.

结果］在血瘀状态下，可在一定程度上抑制原发肿瘤的生长，荷瘤肝转移小鼠血清IL18和HGF的水平降低，可能干预了肝转移的过程，参三七醇提液对荷瘤肝转移大鼠的脾脏原发肿瘤的生长和肝转移有一定抑制作用，血小板在肿瘤增殖、浸润和转移中起着重要作用。

Allabove indicated that the more antitumor ability of PELs was not theirmount,perhaps,but their quality.

以上这些说明微环境中一定水平IL-2的存在能使肿瘤的细胞免疫应答速度加快，免疫细胞获得杀伤能力所需时间短并伤百分率高，从而使在这种微环境中肿瘤细胞的生长明显受到抑制，同时也说明mIL-2〓诱导的PEL抗肿瘤能力，并非是通过免疫细胞数量上的增加来实现。

The major researching subjects are the evolution of sex chromosome and genome in mammals, molecular mechanism of tumorigenesis and gene therapy on cancer, signaling in tumorigenesis, development and metastasis and cellular and molecular immunology, and so on.

本学位点的主要研究方向有：一、动物染色体进化与基因组学；二、肿瘤发生的分子机制与肿瘤的基因治疗；三、肿瘤的发生、发展及转移的信号转导调控；四、细胞与分子免疫学等。

Methods: Mice bearing in vivo transplanted tumor-H22 hepatic carcinoma were used to evaluate the drug"s activity of anti-tumor and GAPSGF"s efficacy enhancing effect by calculating the ratio of antitumor and q. HE dyeing was applied to observe the tumor"s morphological changes after the anti - tumor drug. It is observed the change of theperipheral white blood cells in serum and the body weight to analyze the GAPSGF"s toxicity reducing effect on the anti - tumor drug-Cytoxan. Applying ELISA method to observe the change of IL-2 in serum ,Applying carbon clearance method to test the function of uninuclear phagocyte,took the weight of the spleen and thoracic gland, analyzed the mechanism — efficacy enhancing and toxicity reducing of GAPSGF.

构建体内动物移植性H_(22)肝癌模型，通过计算抑瘤率与q值来分析药物的体内抗肿瘤活性，判断树舌多糖GF注射液的增效作用；采用瘤组织常规HE染色观察药物作用下的肿瘤细胞形态变化；观察外周血WBC数和体重改变来分析树舌多糖GF注射液对环磷酰胺抗肿瘤的减毒作用；采用ELISA法测定血清IL-2、小鼠碳粒廓清法测定单核吞噬细胞功能、取胸腺与脾脏称重测定脏器指数等以分析树舌多糖GF注射液增效减毒的作用机制。

Vascularization of tumor is the key step for a tiny local neoplasia turning to an enlarged tumor capable of metastasis.

因此，肿瘤的血管化是新生物从小的局限的肿瘤转变为具有转移能力的增大的肿瘤过程中的关键步骤。

It was also showed that Moxibustion and the combined treatment could not only promote the immune functions of tumor-bearing organism, but also exsert its influence on the biological characteristics of tumor cells, which gave a new scientific explanation to the traditional Chinese medicine theory of "supporting the energy of life to expell the evil factors" in the treatment of malignant tumors.

本工作的结果表明，进行针灸抗肿瘤的疗效和机理研究，不仅要考虑其对机体免疫功能的良性调整作用，同时还要着眼于其对肿瘤细胞生物学特性的影响，这样才能更全面地评估针灸的抗肿瘤作用及其机理。

In intravesical radioimmunoimaging T/NT value provided a new means for determining the extent of malignant bladder tumor. It may be useful for the early diagnosis, the choice of treatment and evaluation of prognosis in bladder cancer.

在膀胱癌RII中，通过定量方法判断诊断结果可提高对较小肿瘤的诊断灵敏度，可判断膀胱肿瘤的恶性程度，有助于肿瘤的早期诊断和治疗方案的选择及预后的评价。

Then they examined PTEN in nonhereditary breast tumors from 297 patients and tumors from 34 women who had inherited the BRCA1 mutation. In most cases, the protein that PTEN produces was undetectable in tumor cells, but clearly present in nearby normal cells.

然后他们检查了297名患非遗传性乳房肿瘤的妇女和34名遗传了BRCA1变异并患肿瘤的妇女，发现在大多数情况下，肿瘤细胞里检测不到由PTEN产生的蛋白质，但在附近正常细胞的周围明显存在由PTEN产生的蛋白质。

Nowadays the therapy of malignant brain tumors is still a challenge to neurosurgeons. One of the most important reasons is the initial mechanisms of brain tumors have never been well illustrated.

脑肿瘤，特别是恶性脑肿瘤的治疗目前仍是临床医生面临的一个难题，重要的原因之一是由于对脑肿瘤的发生发展机制尚不明了。

Do you know, i need you to come back

你知道吗，我需要你回来

Yang yinshu、Wang xiangsheng、Li decang,The first discovery of haemaphysalis conicinna.

1〕 杨银书，王祥生，李德昌。安徽省首次发现嗜群血蜱。