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Aim To study the expression of CD44V6 and Cathepsin D in early and advanced gastric carcinomas, and their prognostic significances.

肿瘤的侵袭和有无淋巴结转移是恶性肿瘤致患者死亡的主要原因,探讨能评估肿瘤转移的指标,是研究肿瘤预后的关键。

In this system, the consistencies of nutrition and restrainer satisfied two elliptic equations, but the tumor growth satisfied the Stefan condition on the boundary of the tumor field.

在这个问题中,肿瘤生长环境内部的营养物、抑制物浓度分别满足两个椭圆型方程,但是在肿瘤的边缘——该问题的自由边界,肿瘤的生长状态满足Stefan条件。

The frequency of losing exon 5-8 was the highest . It was consistent with the results of the FHIT gene whole length cDAN by RT-PCR.Conclusions: The above results showed that the changes of FHIT gene is probably related to the development of kinds of tumors, which is an important molecular event. FHIT gene can be considered to be a tumor suppresser gene, our studys provided a theoretic and experimental data for further research on the function of FHIT gene.

结论本研究结果初步证明FH工T基因改变可能与多种肿瘤的发生有关,是肿瘤发生的一个重要的早期分子事件,支持其作为一个抑癌基因在肿瘤发生中发挥作用,为进一步深入研究FH IT基因的功能提供了理论和实验依据。

The drug concentration in the janitrix and the abdoninal cavity is higher than that in the abdoninal aorta and peripheral venous after the treatment.The tissue of liver is about the same to kidney .The durg concentration in the janitrix and tissues is high and invariant for a long time. TACE and sequential chemotherapy inhibit the development of the cancer synergily and the latter cannot induce the toxic reaction.

化疗药物腹腔给药后门静脉血中,腹腔液中药物浓度显著高于腹主动脉,外周静脉血;腹腔给药后,肝组织中药物浓度高于肾组织;药物在门静脉,组织中存在较高的药物浓度,递减缓慢,浓度恒定,维持时间长;肝动脉化疗栓塞术有效地控制了肿瘤的大小,序贯化疗亦有效地抑制了肿瘤的发展和转移,两者间作用相互协同;序贯化疗不增加肿瘤病人的化疗毒副反应。

Results: Small intestinal tumors with gastrointestinal bleeding had the following clinical characteristics:(1) Melena was more common;(2) Most of the patients were over 40 years old;(3) Benign tumors were more common;(4) Smooth muscle tumors is more common in the benign tumors which majouryly located injijunam.

结果 :以消化道出血为主要症状的原发性小肠肿瘤的临床特点:(1)以便血为主;(2 )大多数在 4 0岁以上;(3)以良性肿瘤为多见;(4)良性肿瘤多为平滑肌肿瘤,主要位于空肠,而恶性肿瘤多位于回肠,以淋巴瘤和腺癌多见;(5 )消化道出血的时间和出血量与肿瘤的大小、性质无关。

Hepatic cirrhosis, virus hepatitis, alcohol, adipositas, diabetes mellitus, non-Alcoholic fatty live, flavacin and other chemcial carcinogens or water and soil factor are the nanocephalous cause of hepatocarcinogenesis which has been generally accepted.

HDAC6作为组蛋白脱乙酰化酶家族一员通过微管去乙酰化和HSP90的去乙酰化调控基因转录,改变细胞的运动能力从而参与肿瘤发生发展和肿瘤的转移以及肿瘤血管的生成。

Methods: Serum samples were collected from 146 cancer patients who were treated in our studying group from April to December, 2004. Serum samples were added to a weak cation exchange 2 (WCX2) protein chip and analysed on the Protein Biology System surface enhanced laser desorption ionisation time of flight mass spectrometer (SELDI-TOF-MS) manufactured by Ciphergen Biosystems Inc.

人类肿瘤蛋白质组的研究是目前恶性肿瘤研究的重要方法之一,利用蛋白质飞行质谱技术(SELDI-TOF-MS)检测某种肿瘤蛋白质组的质谱变化,用于肿瘤的早期发现,已有不少报道[1]。

When no angiogenesis, solid tumor growth will Be inhibited so obviously that it is limited to carcinoma or tiny metastasis of several hundred micra; on the contrary, if having angiogenesis, tumor will grow rapidly, whacs more, its nature of soakage and metastasis will be enhanced greatly.

新生血管为肿瘤的生长、转移提供氧和营养物质,在无新生血管生成时,实体肿瘤的生长明显被抑制,只局限于原住癌或几百个微米的微转移;而一旦新生血管长入,肿瘤将迅速生长,且浸润和转移的能力大大加强。

However, the study about the relationship between the number of TILs and non-small-cell lung cancer is very few, especially between CD4~+、 CD8~+T lymphocytes and NSCLC.

研究发现某些肿瘤(如,食道癌、胰腺癌、结肠直肠癌)浸润淋巴细胞(tumor infiltrating lymphocyte,TIL)的数量和T细胞亚群与肿瘤的预后有明显的关系,但肿瘤浸润淋巴细胞,特别是CD4~+、CD8~+T细胞亚群与非小细胞肺癌(non-small-cell lung cancer,NSCLC)预后的研究很少,说法不一。

So it may be necessary to block the overexpression of the VEGF in tumor cells with ribozyme technique,thus to prevent the cells from over proliferation,and search for a new treatment of the ovarian cancer.

因此,采用核酶技术阻断卵巢肿瘤细胞中VEGF的过量表达,有可能阻止肿瘤细胞的增殖,为卵巢肿瘤的治疗开创一条新途径。

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