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New criteria, known as RECIST (Response Evaluation Criteria in Solid Tumours), were published in 2000.8 Key features of the original RECIST include definitions of minimum size of measurable lesions, instructions on how many lesions to follow (up to 10; a maximum five per organ site), and the use of unidimensional, rather than bidimensional, measures for overall evaluation of tumour burden.

新的标准,也称为RECIST(实体肿瘤的反应评价标准)于2000年出版。最初的TECIST关键特征包括病变最小大小的确定、对随访病变数目的建议(最多10个;每个器官最大5个)、一维而不是二维的使用、肿瘤负荷的总体评价。

Cases presenting as peritoneal carcinomatosis with unknown origin are always a challenge for the physicians to select the most appropriate method to make the diagnosis. In this particular case, the pathological report obtained directly from the incarcerated tumor implant showed the tumor to have arisen most probably from the stomach.

临床上偶而会遇到病患就医即呈现广泛性腹腔内癌性转移的情形,因原始肿瘤的症状不明显,临床上会有诊断及治疗方面的困扰,原始肿瘤未明的广泛性腹腔内癌性转移案例中,虽以胃癌及大肠癌的案例最多,但胰脏癌及妇科方面的案例亦不少,为了诊断及组织切片的取得常需要一些侵袭性的检查如胃镜或大肠镜等,增加病患的痛苦。

CD44 is a single strand glucoprotein family encoded by single gene on the memebrane surface with high heterology,which can mediate adhesion between cell and cell as well as cell and extracellular matrix.Its different splicing variants will result in the variety of its gene products.Especially,its splicing varant V6 (CD44v6) is condided to have oncogenicity.CD44v6 takes part in the genesis and development of tumor at some certain and is one of prognostic factors.So it will be the marker indicating tumor development.

CD44是由单一基因所编码的具有高度异质性的单链膜表面糖蛋白家族,介导细胞与细胞、细胞与细胞外基质之间的黏附作用,其拼接变异体的不同构成了其基因产物的多样性;尤其拼接变异体V6(CD44v6)被认为具有致瘤性;CD44v6在一定程度上参与了肿瘤的发生发展,是预后因子之一,并且可能作为肿瘤进展的标志物。

It has opened a new way for the diagnosis and therapy of tumours, and also estab- lished the foundation for the carcinogenic mechanism research. In order to study the altered molecular events during laryngeal car- cinogenesis and elucidat the role of oncogenes in laryngeal carci- noma, we examined the Ha-ras and c-myc gene mutation and amplification by the polymerase chain reaction and molecu- lar hybridization technigues respectivly.

癌基因的研究是当前肿瘤领域内的重大课题,正在基础理论和临床医学中进行广泛和深入的研究,癌基因的发现为肿瘤的诊断和治疗开辟了新的途径,同时也为人类开始从分子水平来回答细胞癌变的本质问题,最终认识癌变机制奠定了理论基础。

We speculate rapid pneumoperitoneum introduction pushed CO2 into the abnormal vasculature, which communicates with systemic vascular system, causing a new pseudoaneurysm formation inside the tumor and gas embolism appearance.

我们臆测快速的二氧化碳充气制造气腹,可能将CO2 推入异常的肿瘤血管而产生pseudoaneurysm,而肿瘤的异常血管和身体的血液循环是相通的,可能产生气体栓塞。

This malignancy is characterized by concomitant existence of carcinomatous and sarcomatoid components. Complete tumor excision typically leaves a considerable defect. This report presents a case of a 60-year-old male with carcinoscarcoma of the right chest wall who underwent wide excision. Reconstruction was achieved with lateral thoracic fasciocutaneous flap applied in a bibbed manner that allowed for low tension on the anastomosis.

这类肿瘤的特色是同时含有癌症及类肉瘤的成份所组成,肿瘤完全切除后通常会遗留下可观的缺损,我们提出一个60岁男性病患利用双叶侧胸动脉皮办重建胸部癌肉瘤的病例报告,双叶性的设计有助於伤口张力的降低。

However, for some reasons, a mouse may die before the end of the trial, or may lose the nessary to go on the trial when its tumor volume quadruples, then the dada is not complete, and the missing data arises. At the same time, for the effect of the drug, the tumor may grow more and more small, and when it reaches a cartain degreefor example

然而,在实验完成之前由于各种原因,实验鼠可能会死去,或者由于肿瘤体积增大到原来的4倍而失去继续实验的意义,这样,测量出的数据就会出现缺失的情况;与此同时,由于药物的作用,肿瘤的体积也会慢慢变小,当减小到一定程度之后

The only report is done by our research team about the distribution regularity of the three kinds of muscarinic receptor subtypes in normal human prostate in 2006 The cholinergic receptor expression was prevalent in many tumors, in which mostly higher than in the normal tissue.

最近几年,关于前列腺癌发生和进展中发生的分子生物学改变方面的知识增加迅速,对肿瘤分子生物学更好的理解对于建立新的对策来延缓或抑制肿瘤的进展具有重要的意义。

These results provide some new supports for us to raise the treatment effects of adoptive immunotherapy with TILs induced by IL-12 and activated by DC on tumors and they will give us an instruction on clinical applications.

由此可见,IL*二和DC能增强TIL特异性杀伤肿瘤细胞的作用,该研究结果为肿瘤的TIL过继免疫治疗疗效的提高提供了新的依据,为进一步的临床应用莫定了基础。

With the development of chemiluminescent reagents and detectors, it will be an important method of detecting tumor markers, large influences for earlier diagnosis tumors and be a very important method in clinical laboratory.

随着发光试剂与检测仪器的不断进步,化学发光法研究也在不断深入发展,作为检测肿瘤标志物的一种重要方法,将为肿瘤的早期诊断以及愈后的监测发挥更重要的作用。

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