肿瘤的

It is characterized by malignant unusual hyperplasia and soading of cells in medulla ossium and other tissues, which can damage the normal hemopoiesis function and the mechanism of blood coagulation fibrinolysis and immunology.

机体的免疫功能与肿瘤的发生和发展有密切关系，当宿主免疫功能与肿瘤的发生和发展有密切关系，当宿主免疫功能低下或受抑制时，肿瘤发病率增高，而在肿瘤进行性生长时，患者的免疫功能进一步受到抑制。

Hypoxia induces the resistance of tumor cells[4];and the heterogeny of solid tumors result in the appearance of subpopulations of differentproliferative potency in the same tumor tissue, so that the target cells sensitive to cell cyclespecific drug are reduced.

目前有研究认为：实体瘤部分细胞缺氧和肿瘤组织的异质性可能是导致肿瘤对放疗和化疗产生耐受的主要原因之一，缺氧可以诱导肿瘤细胞对放疗和化疗的耐受性[4]，实体肿瘤的异质性可使同一瘤组织内具有不同增殖潜能的癌细胞亚群存在，导致细胞周期特异性化疗药物作用的靶细胞减少。

Genesis,development and metabasis of solid tumor have close relationship with tumor vessel angiogenesis; extracellular matrix degradation is the key point for tumorous infiltration and metabasis;the significant biology characteristic of tumor cell is the disorder of tumor cell differentiation and apoptosis.

骨巨细胞瘤血管生成是近年来研究热点，实体瘤的发生、发展及转移与肿瘤的血管生成密切相关；细胞外基质降解在肿瘤的浸润和转移中起到关键作用；肿瘤细胞的分化凋亡障碍与无限增殖能力是肿瘤细胞的重要生物学特征。

Correlation of histotypes of phyllode tumor with local recurrence and tumor death was statistically significant at a level of P＜0. 001; correlation of infiltrative growth of the tumor with local recurrence was statistically significant at a level of P＜0. 001. Tumor necrosis and mitotic activity were independent prognostic factors.

叶状肿瘤的病理组织学等级与肿瘤的局部复发和因瘤死亡有统计学线性关系(P＜0.01)；肿瘤的浸润性生长方式与肿瘤的复发有线性关系(P＜0.01)；肿瘤性坏死和核分裂数值是独立的预后因素；术式等11个临床病理因素为单风险预后因素。

objective:our aim is to investigate the relationship of vegf c,vegf d and lymph node metastasis in pancreatic cancer,and to elucidate the role and significance of the cancerous peripheral lymphatic tissue.methods: the expression of vegf c and vegf d was assayed by means of immunohistochemistry in 30 pancreatic carcinomas.results:the positive rates of vegf c、vegf d were 73%(22/30)、57%(17/30) respectively in pancreatic cancer.the expression of vegf c、 vegf d in cancerous invasive edge was significantly higher than that in the center of cancerous tissues.there was no correlation between the expression of vegf c、vegf dand the site,differentiation,histology types.

目的：探讨胰腺癌中vegf c、vegf d蛋白表达与淋巴结转移之间的相关关系，阐明癌周淋巴管增生在胰腺癌淋巴转移中的作用及意义。方法：免疫组化检测30例胰腺癌组织中vegf c、vegf d的表达及其与临床病理、淋巴结转移的关系。结果：胰腺癌vegf c、vegf d蛋白表达阳性率分别为73%(22/30)、57%（17/30），肿瘤周边部位显著高于肿瘤中心部位，其表达与肿瘤的部位、分化程度、组织学类型无关，与肿瘤的tnm分期有关，ⅲ~ⅳ期显著高于ⅰ~ⅱ期。

Hepatocellular carcinoma is a well-known hypervascular tumor ,and easy to produce invasion and metastasis. However, the combined examination of VEGF, Flk-1, Flt-1 and nm23-H, in HCC and the relationship with MVD, growth and metastasis has not been reported up to now.

许多研究表明，VEGF与肿瘤的微血管密度(Micro-Vessel Density，MVD)紧密相关，与肿瘤的生物学行为密切相关。nm23-H_1是一种抑制肿瘤转移的基因，它在许多高转移肿瘤细胞株中比相应的低转移细胞株低表达。

Often women with small tumors undergo lumpectomy to have the tumor removed.

通常，患有乳腺小肿瘤的女性接受乳房肿瘤切除术以去除肿瘤。

The expression of vegf in xenograft tumor cells was analyzed by indirect immunofluorescence.

近40年来在肿瘤领域研究的重大进展之一是确立了肿瘤血管生成在肿瘤发展中的重要地位与抗血管生成治疗肿瘤的意义［1，2］。

Statistical data of TF grading scores showed that its expression was not significantly related to the size and location of glioma, sex, and age of patients, but closely related to the glioma gradings and microvessel quantity of the tumor.VEGF was found in gliomas of all gradings and its expression was significantly enhanced with the increase of glioma gradings.

TF分级计数统计结果显示其表达与肿瘤的大小、部位及患者性别、发病年龄等临床因素无显著相关性，但与肿瘤的分级及肿瘤微血管数量密切相关。2、VEGF在各级胶质细胞瘤组织中均有表达，随着肿瘤组织学分级的增加，VEGF的表达明显增强。

Background During the tumor angiogenesis and haematogenous metastasis, there exist complicated interactions between tumor cell and vascular endothelial cell. They interact and make joint efforts to contribute to establish the tumor vascular network and induce tumor invasion and metastasis.

研究背景：在肿瘤的血管系统建立和血行转移中，肿瘤细胞与血管内皮细胞之间存在复杂的相互关系，他们相互作用以促使肿瘤内血管网的出现和肿瘤的侵袭转移。

They weren't aggressive, but I yelled and threw a rock in their direction to get them off the trail and away from me, just in case.

他们没有侵略性，但我大喊，并在他们的方向扔石头让他们过的线索，远离我，以防万一。

In slot 2 in your bag put wrapping paper, quantity does not matter in this case.

在你的书包里槽2把包装纸、数量无关紧要。