肿瘤样的

Through all this test analyse Pathogenicity and Immunological status of ALV-J Inner Mongolia strain, the result showed the infected chickens began to have pathological change of Myelcytomatosis at 3-week: the main pathological changes of acidophile myelocyte were found in bone marrow and between cardiac muscle fibers,and there were many granules in the hyalotome.This kind of oncocyte proliferated in every tissue at different amount, but the cells that proliferated in bone marrow, cardiac muscle fiber, oarium were much more than other tissue, and they often developed neoplasma. At same condition,there were no abnormalty advent in control group, In immunological aspect: the increase of lymphokine and ANAE positive cells showed cell-mediated immunity was strengthend during antineoplastic infection; the emergence of ALV-J antibody of ELISA suggest there was humoral immunity exist at the same time.

结果显示：脾脏PCR检测结果表明1、2两实验组均有阳性病例出现，而对照组全部为阴性，说明实验鸡体内已有ALV-J内蒙株感染；接种病毒后3周龄开始出现骨髓细胞瘤病的病理变化：肝脏、脾脏有程度不同的肿大，镜下观察，骨髓内最早出现了与骨髓细胞相似、形态基本一致的大型圆形或椭圆形、胞核较大多为椭圆形、胞浆内含有大量嗜酸性圆形颗粒的髓细胞样瘤细胞增生，随后通过血流瘤细胞可转移到肝脏、心肌、卵巢或睾丸等组织并形成肿瘤性病灶，而对照组没有出现明显病变；免疫状态方面：以脾脏淋巴因子和ANAE阳性细胞增多说明细胞免疫在抗肿瘤感染过程中增强，ELISA检验实验鸡抗体出现阳性的结果表明同时也存在着体液免疫。

I am impressed with the nested nature and intracytoplasmic mucin like material and signet ring cells.

尽管我也考虑到其他疾病的可能，但我会告诉手术医生，肿瘤是伴有印戒样细胞特征的癌，支持转移性的（乳腺、胃肠道，如果宫颈原发癌是腺癌，首先考虑为宫颈转移）。

Dept of Pathol, Hangzhou First Hospital, Hangzhou ,310006ABSTRACT Purpose To observe the clinical pathologic characteristics of palisaded myofibroblastoma, approach its histogenesis and the nature of the amianthoid fibers.

摘要，目的：观察栅状肌纤维母细胞瘤的临床病理特征，探索该肿瘤的组织来源及石棉样纤维的性质和来源。

2The involvement of MFT in woman is more than that in man.(3)The patients showed multiple dome-shaped, skin-colored, firm papules on the face. Some patients also present the lesions on the scalp and neck. No lesion showed the malignant tendency.(4) The histologic findings of MFT are cornified cysts and some nests of basaloid epithelial cells.(5)There were variable clinical expressions in different patients of the same family.(6) Some pedigrees were also affected by feckle or symmetrical progressive erythrokeratoderma, which were not found in MFT patients of other origin.

MFT临床分析总结：①MFT遗传方式为常染色体显性遗传；②女性发病多于男性；③中国汉族人MFT的典型皮损特征为面部乳白色半球形或圆锥形丘疹，质地坚实，只有2个家系皮损分别发生于头皮及颈部，均无恶化倾向；④组织病理特征为角质囊肿和由基底样瘤细胞构成的肿瘤岛；④同一家系中不同的患者表现度不同；⑤个别家系可伴发雀斑及进行性对称性红斑角化症，其它家系不伴发其他疾病。

What was observed under a light microscope included: tumor cells were mulberry and micropapillary shaped or it was of glandule tubular arrangement; there was obvious interspace between cancer nest and neighboring areas; micropapillary was empty of fiber blood vessel axes; immunohistochemical staining showed ema positive location was both at outward surface of glandule duct and at micropapillary like cancer nest.

光镜下特征性表现为肿瘤细胞呈桑椹状、微乳头状或小腺管样排列，癌巢与周围间质形成明显的空隙。微乳头缺乏纤维血管轴心。免疫组化染色ema阳性部位在癌细胞巢团或微乳头状、腺管的外表面。

Myoid/myofibroblastic areas in DFSP possibly represents the hyperplasia of stromal myofibroblasts, rather than true myofibroblastic differentiation of the neoplastic cells.

DFSP中的肌样／肌纤维母细胞性分化可能是肿瘤间质中肌纤维母细胞增生的结果，并非代表了瘤细胞的真性肌纤维母细胞性分化。

All 31 YSTs (5 pediatric and 26 postpubertal) showed strong positive SALL4 staining in more than 90% tumor cells but had negative OCT4 staining. Both spermatocytic seminomas showed positive SALL4 staining in 80% to 95% tumor cells in all 3 types of tumor cells with weak-to-moderate staining intensity.

为了检验SALL4的特异性，我们还给23例睾丸的非GCTs（10例间质细胞瘤、4例支持细胞瘤、3例腺瘤样瘤、3例睾丸旁横纹肌肉瘤、2例弥漫性大B细胞瘤、1例睾丸网的乳头状囊腺瘤）和275例非睾丸性肿瘤（158例转移癌、12例转移性黑色素瘤、11例原发性和2例转移性间皮瘤、72例原发性和20例转移性肉瘤）做了SALL4免疫染色。

All patients underwent surgical resection of the entire tumor. Two patients with MCa and sarcoma or sarcomatoid carcinoma received chemotherapy.

所有患者的肿瘤都进行了全切，患MCa并伴肉瘤或肉瘤样癌的2位患者进行了化疗。

To be qualified as an EOS, the tumor must (1) arise in the soft tissue and not be attached to bone or periosteum,(2) have a uniform sarcomatous pattern ( to exclude the possibility of a mixed malignant mesenchymal tumor),(3) produce osteoid and/or cartilage matrix.

本病的诊断标准是(1)发生于软组织而与骨及骨膜部不相连；(2)具有一致的骨肉瘤表象，以排除混合性恶性间叶组织肿瘤；(3)可产生骨质或软骨样基质。

For tumors which have been well sampled and exhibit (1) a microcystic pattern and regions with lobulated cellular masses with intervening, sometimes hyalinized fibrous stroma,(2) an absence of morphologic features enabling any other specific diagnosis in the sex cord-stromal category,(3) an absence of epithelial elements, and (4) an absence of teratomatous or other germ cell elements, we propose the designation microcystic stromal tumor.

我们很好地抽样调查了4例肿瘤，显示：（1）微囊样式和有时插入玻璃样变的纤维间质中的分叶状细胞团区，（2）能造成在性索间质这个大类中其他具体诊断的形态特征缺失，（3）上皮成分缺失，（4）畸胎或其他胚芽细胞成分缺失，我们提议定其名为微囊性间质瘤。

Plunder melds and run with this jewel!

掠夺melds和运行与此宝石！

My dream is to be a crazy growing tree and extend at the edge between the city and the forest.

此刻，也许正是在通往天国的路上，我体验着这白色的晕旋。