肿瘤

Though the surgery and bladder instillation are effective to many patients, the recurrence and morbility are still high.

此外，尽管膀胱癌的治疗有手术、膀胱内药物灌注等方法，但膀胱癌患者肿瘤复发率及死亡率仍较高，特别是晚期膀胱肿瘤患者缺乏有效的治疗方法。

Methods From June 2000 to June 2005,50 cases with GIST received operation were analyzed retrospectively.The tumors＇ diameter, morphous and immunohistochemistry were reviewed.

回顾性分析2000年6月～2005年6月50例GIST病人均行手术治疗，术后对50例切除标本进行横径检测；光镜下观察50例肿瘤细胞形态：对肿瘤细胞进行免疫组化检测。

AIM To study the long-term toxicity of modified recombinant human tumor necrosis factor rhTNF-NC in Macaca mulatta compared with recombinant human tumor necrosis factor rhTNF.

目的 研究新型重组人肿瘤坏死因子rhTNF-NC iv对恒河猴的长期毒性，并与重组人肿瘤坏死因子rhTNF作比较。

objective to evahiate the diagnostic value of us in malignant mixed mullerian tumor.methods 17 cases with mmmt were proved by surgery and pathology studied retrospectively and their ultrasonographic features were mainly reviewed.results of the 17 cases, 11 cases were in uterus, 3 cases were in cervixes,l case fallopian tubes,2 cases in ovaries.us can well demonstrate the extent、border and the relationship with adjacent tissue.conculusion the results showed that the 2 d and cdfi can provide valuable information in diagnosing.

摘 要］目的：探讨女性生殖系统恶性mullerian混合瘤的超声图像与病理组织类型的关系，以期为临床诊断提供准确的参考依据。方法：回顾性分析经手术和病理证实的17例女性生殖系统恶性mullerian混合瘤超声特征，并与病理学组织类型进行对比研究。结果：17例病例中发生在子宫体11例，子宫颈3例，输卵管1例，卵巢2例。二维超声能清楚显示肿瘤部位、大小范围、边界以及与临近结构的关系。结合彩色多普勒对肿瘤性质的判定具有重要意义。

Tumors in patients with HCV are multinodular and less differentiated, and were associated with a higher incidence of vascular invasion and cirrhosis.

肝内复发肿瘤为多发者在HCV感染组发生率最高（占肝内复发肿瘤的66.0%），其次为HBV+HCV感染组（28.6%），HBV感染组（23.3%）及无感染组（17.6%）。413例小肝癌患者术后1、3、5年总生存率分别为89%、70%和61%，HCV感染组预后最差。

We have previously showed that CD40 activation induced the cell fusion and formation of multinucleated giant RS like cells from B lymphoma Daudi cells, which makes it clear that the Daudi cells obtained the ability of invasion after CD40 triggering.

CD40分子激发后的恶性B淋巴母细胞Daudi发生自身融合现象，表明肿瘤细胞在CD40分子激发后获得了某种侵润能力。而恶性B淋巴细胞的特性之一就是肿瘤细胞的广泛转移和侵润。因之，我们推测淋巴细胞的CD40分子激发可能对其扩散和转移会产生影响。

Although a few TK genes have been shown to be mutationally altered in specific human cancers (1), it is not known how many or how often members of the TK gene family are altered in any particular cancer type.

尽管有少数TK基因被报道在特定的人类肿瘤中有突变，但对整个TK基因家族中有多少个基因多少次在某一特定肿瘤类型中有突变，还是个未知数。

Thus, IDH1 appears to function as a tumor suppressor that, when mutationally inactivated, contributes to tumorigenesis in part through induction of the HIF-1 pathway.

因而IDH1似乎是作为一种肿瘤抑制因子而存在，一旦通过突变使之灭活，则可能会部分的通过HIF-1α途径参与肿瘤的发生。

Thus, IDH1 appears to function as a tumor suppressor that, when mutationally inactivated, contributes to tumorigenesis in part through induction of the HIF-1 pathway.

因而异柠檬酸脱氢酶-1(IDH1)似乎是作为一种肿瘤抑制因子而存在，一旦通过突变使之灭活，则可能会部分的通过缺氧诱导因子亚单位α（HIF-1α）的途径而参与肿瘤的发生。

Thus, IDH1 appears to function as a tumor suppressor that, when mutationally inactivated, contributes to tumorigenesis in part through induction of the HIF-1 pathway.

研究者认为，IDH1具有肿瘤抑制子的作用，一旦IDH1发生突变失活则导致HIF-1通路发生改变促进肿瘤发生。

Do you know, i need you to come back

你知道吗，我需要你回来

Yang yinshu、Wang xiangsheng、Li decang,The first discovery of haemaphysalis conicinna.

1〕 杨银书，王祥生，李德昌。安徽省首次发现嗜群血蜱。