肿瘤

Gastric intraglandular neoplasia is induced in primates when H pylori infection is associated with consumption of a carcinogen similar to the nitrosamines found in pickled vegetables, suggesting that H pylori and the carcinogen synergistically induce gastric neoplasia in primates.

HP感染配合喂食与泡菜和熏肉中相似的致癌物诱导了胃部腺内肿瘤，提示HP和该致癌物对恒河猴胃部肿瘤的协同诱导作用。医学岛推荐原文

Results CT showed a intrapelvic mass of rectal wall or surrounding soft tissue with inequality of size, relation closeness with intestinal wall; rectall wall different degree compression and narrowing,and extruding surrounding tissue.Below 5cm tumor density were slightly reduced,but symmetrical. Exceed 5cm tumor moderately enhanced, but asymmetrical. CT value of major mass were 25-35Hu, with boundary zone nodule enhancement, contrast-enhanced CT value 50-60Hu, and centricity necrosis.

结果 （1）盆腔内直肠壁或直肠周围软组织肿块，大小不等，肿块与直肠壁关系密切；（2）直肠不同程度的受压、变窄，肿块主要向直肠腔外生长，对周围组织产生推挤压迫；（3）径线在5cm以下肿瘤平扫时密度稍低，但均匀，增强时表现为中等度均匀强化，无坏死；径线在5cm以上10例肿块密度平扫时呈稍低密度且不均匀，CT值25-35Hu，增强时较大的肿瘤边缘带中等度结节样强化，CT值50-60Hu，肿块中心部分无强化，呈坏死样改变。

For patients with superficial bladder cancer, the doctor may use intravesical chemotherapy after removing the cancer with TUR.

对于浅表性膀胱癌的患者，医生可能会在经尿道肿瘤切除术切除癌症后使用灌注化疗的肿瘤切除。

There are 10-41% of bladder tumors recurrence, although treatment of bladder tumors with intravesical BCG.

虽然BCG灌注改进了膀胱肿瘤的临床治疗效果，但仍有10—41％的膀胱肿瘤复发。

RESULTS:Isoalantolactone exhibited excellent anti-proliferative activities on HeLa, SHIN3 and HOC-21 and HAC-2 cell lines, while 1-O-acetylbritannilactone and britannilactone demonstrated weak anti-proliferative activities on HeLa, SHIN3, HOAC-21 and HAC-2 cell lines even at the concentration of 100 μmol/L. The apoptotic rate in isoalantolactone group with the concentration of 12.5 μmol/L was higher than that in PBS group.

结果： 异土木香内酯对上述5种肿瘤细胞的增殖均有明显的抑制作用，1-氧-乙酰大花旋覆花内酯和大花旋覆花内酯即使在100 μmol/L的高浓度下，对5种妇科肿瘤细胞的增殖不显示抑制活性；流式细胞学检查发现异土木香内脂处理后的HeLa细胞出现凋亡现象。

Objective To evaluate and compare the ability to detect tumor by bis (N-ethoxy-N-ethyl dithiocarbamato) nitrido 99mTc [ 99mTcN 2 ] and 99mTc hexakis-2- methoxyisobutyl isonitrile [ 99mTc-MIBI ].

目的 探讨99mTc-氮-二(N-乙基-N-乙氧基二硫代氨基甲酸盐)[99mTcN2]应用于肿瘤诊断的可能性并与99mTc-甲氧基异丁基异腈(99mTc-MIBI)肿瘤模型显像进行比较。

Enhanced CT imaging features were distinguished, and isopycnic density and low-density tumors were all displayed. Among 26 cases, the tumor diameter of 3 ~ 6cm was 22 cases , 1 ~ 3cm 4 cases; arterial phase scans had uneven reinforced, also had signs of peripancreatic fat layer disappeared, pancreatic duct and bile duct dilatation, bile duct obstruction, combined pancreatic cyst, tumor invasion blood vessels, peritoneal and lymph node metastasis.

增强CT影像特点显著，等密度及低密度肿瘤均得到显示。26例中，肿块直径3～6cm 22例、1～3cm 4例；动脉期扫描有不均匀强化，另有胰周脂肪层消失、胰管和胆管扩张、胆总管阻塞、合并胰腺囊肿、肿瘤侵及血管、腹膜的淋巴结转移等征象。

The method can help pathologists work.By the CAD system presented in the thesis, 95.7% karyon and 93.8% cytoplasm are segmented successfully from cell images. The sorting result of suspicious tumor cells is correct in principle.

作者所研制的&肿瘤细胞辅助诊断系统&中，细胞核和细胞浆的分割成功率分别为95.7%和93.8%，对疑似肿瘤细胞的排序结果基本正确。

Under electron microscope, tumor cell emerged karyopyknosis, new-moon shaped or circular, nucleus membrane was clesr, endoplasmic reticulum was dilated, and mitochondrion was swollen. A lot of apoptosis cells emerged in the tumor foci under light microscope.

光镜下显示肿瘤灶中出现许多凋亡细胞；肿瘤组织电镜观察，瘤细胞核染色质浓集成块，在核膜内呈新月形或环形排列，核膜清楚，瘤细胞内质网扩张，线粒体肿胀。

Results HE staining showed that sulindac could inhibit the growth of tumor cells, with the morphological presentations as apoptosis and necrosis including pyknosis, karyorrhexis and chromatin crescent formation, etc. By electron microscopy, cells also had apoptotic characteristics including chromatin crescent formation and apoptotic body. Immunohistochemistry and Western-blot assay results showed that 48 hours after sulindac administration, the expression of NF-κB, bcl-2 and bax gradually decreased, while the level of bax protein gradually increased, in a dose dependence manner.

结果 苏木精－伊红染色检测结果显示舒林酸抑制肿瘤细胞生长，肿瘤细胞出现核固缩、核碎裂、染色质边集等凋亡及坏死的形态学表现；电镜下可看到染色质边集、凋亡小体；免疫组化、Western-blot结果显示舒林酸作用48 h后人胃癌SGC-7901细胞NF-κB、bcl-2表达逐渐下降，bax表达逐渐上升，具有剂量依赖性。

Do you know, i need you to come back

你知道吗，我需要你回来

Yang yinshu、Wang xiangsheng、Li decang,The first discovery of haemaphysalis conicinna.

1〕 杨银书，王祥生，李德昌。安徽省首次发现嗜群血蜱。