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When our inert fluorescently labeled CPPs reach the tumor, the tumor cells cut through the linker and thus unleash and take up the CPP.

当惰性的荧光标记的穿膜肽碰到肿瘤时,肿瘤细胞就会经过连接部分,解开并携带上穿膜肽。

Weightlessness simulated; Stomach neoplasms; Tumor cells, cultured; Cell size; Proliferating cell nuclear antigen; Cell cycler Apoptosis

失重模拟胃肿瘤肿瘤细胞,培养的细胞大小增殖细胞核抗原细胞周期脱噬作用

Results Residual cancer cells can be observed in all 17 cases of the radical cystectomy specimen,which located on the conceal ar...

结果在膀胱全切标本中除肉眼观察到肿瘤的4例标本外,其余13例镜下均观察到有肿瘤存在。

Objective: To study the clinical and CT characteristics of solid and cystic tumor of pancreas.

目的:探讨胰腺囊实性肿瘤的临床特征和CT表现,提高对胰腺囊实性肿瘤的认识。

Objective: To investigate the expressions of MUC1 in human carcinoma of bladder and cystitis glandularis and their significance.

目的:检测粘蛋白MUC1在膀胱肿瘤和膀胱良性病变中的表达,探讨其在膀胱肿瘤诊断和免疫治疗中的意义。

Methods 25 patients with upper tract transitional cell carcinoma underwent resection under Laparoscope and cystoscope. Integrity and the detent of ureterostoma was detected after the operation.

对25例肾盂肿瘤或中上段输尿管肿瘤的患者采取腹腔镜联合膀胱镜行肾、输尿管全长切除,术后检查手术标本的完整性,并行输尿管内压力测定,对输尿管口的封闭性进行评估。

IM: To study the effect of tretinoin or retinol on the proliferation of lymphokine activated killer cells in patients with transitional cell cancer of bladder and their cytolysis to bladder tumor cells.

目的:研究维A酸或维生素A对膀胱肿瘤患者淋巴因子激活的杀伤细胞的增殖和对膀胱肿瘤细胞的细胞毒作用。

After incubation with tumor cytolysis antigen ,the DCs can activate the CTLs to become tumor specialized CTLs, which had shown significantly inhibition on growth of YTMLC tumor cell line. Conclusion: The precursors in human cord blood can be induced to functional DCs which activate T lymphocyte to become tumor specialized CTLs.

经细胞因子组合可以从脐血中诱导出DCs,并可诱导肿瘤特异性CTLs的产生而发挥抗肿瘤作用,为进一步开展DCs的基础及临床应用研究打下了基础。

Because different cell lines may show various levels of susceptibility to adenovirus infection and virus production, non-selectively replicating wtAd5 was used to be a comparison with the tested conditionally replicating adenovirus CNHK500.ONYX-015, the first replication-competent adenovirus entered into clinical trials was also used to be a comparison. We used virus proliferation assay, cell viability assay and western blot to evaluate the proliferation and cytolysis selectivity of CNHK500. Results demonstrated that the CNHK500 virus proliferation multiples in breast cancer cell lines after 48 hours is similar to that of wtAd5, ONYX-015 virus proliferation ability is less than that of CNHK500 in cancer cells.

然后,通过与ONYX-015(E1B 55 KD a蛋白缺失的2型和5型嵌和型腺病毒,美国ONYX生化制药公司研制)、wtAd5进行对比,利用病毒增殖实验和细胞生长抑制实验,验证了CNHK500选择性增殖能力和肿瘤特异性杀伤作用;利用Western Blot检测CNHK500腺病毒E1A和E1B在乳腺癌细胞和正常成纤维细胞中的表达差异,揭示了腺病毒肿瘤靶向性的机制;利用携带绿色荧光蛋白的CNHK500-EGFP感染乳腺癌细胞株和正常成纤维细胞株,直观地观察其感染乳腺癌细胞的能力和在乳腺癌细胞中的增殖过程。

The DAK had obviously killing effects on lung cancer cell CALU-6 extracted from TCA.

树突状细胞活化的杀伤细胞对于肿瘤细胞全抗原来源的肺癌细胞系CALU-6肿瘤细胞有明显的特异性杀伤作用。

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