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肿瘤

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When no angiogenesis, solid tumor growth will Be inhibited so obviously that it is limited to carcinoma or tiny metastasis of several hundred micra; on the contrary, if having angiogenesis, tumor will grow rapidly, whacs more, its nature of soakage and metastasis will be enhanced greatly.

新生血管为肿瘤的生长、转移提供氧和营养物质,在无新生血管生成时,实体肿瘤的生长明显被抑制,只局限于原住癌或几百个微米的微转移;而一旦新生血管长入,肿瘤将迅速生长,且浸润和转移的能力大大加强。

The metabolism of AQ4N can actually occur in human tumor microsomes, which provide strong evidence for intratumoral turnover of prodrug in brain tumors.

AQ4N确实可以在肿瘤微粒体内进行转化,并且在原发性及转移性脑肿瘤内有差别,为前药肿瘤微粒体内的药物转化提供了一个很好的证据。

The tumor was removed and the pathology demonstrated highly cellular tumor with poorly differential cells and brisk miotic activity. Based on the tumor location and pathology, a supratentorial primitive neuroectodermal tumor was diagnosed.

经过外科手术切除,病理切片报告确定这是一个原始神经外胚层肿瘤(Primitive neuroectodermal tumors),根据肿瘤位置及病理切片报告诊断为天幕上原始神经外胚层肿瘤

It′s death rate locates the top among gynecological malignant tumors.Mucins is a family of high-glycosylated and high-molecular weight glycoprotein,which is distributed on the surface of body epithelial cells.In cancer cells,the expression of mucins is obviously high and their structures and functions are changed.Mucins are directly implicated in the infiltration and metastasis of ovarian tumors.

黏蛋白是一类高度糖基化、相对分子质量高的糖蛋白,分布于人上皮细胞表面,在卵巢上皮性肿瘤中表达水平明显上调,出现异常表达,其结构和功能发生改变,直接参与了肿瘤的浸润和转移,因而与卵巢肿瘤的发生、发展及预后相关。

In part two, dibenzoxanthene (2~7, 14~16), the oxidation products of naphthols, were found to be of notable anti-tumor activity to several kinds of tumor and relatively lower toxicity to normal tissue, which implied a promising application for new anti-tumor drugs.

在第二部分,体外抗肿瘤活性实验结果显示,萘酚类化合物的氧化产物中,二苯并咕吨类化合物(2~7,14~16)对多种肿瘤细胞具有较显著的细胞毒性和相对较低的正常细胞毒性,具有良好的抗肿瘤新药开发前景。

Bladder cancer is one of the most common diseases treated by urologists.

MDM2、p53和RB基因在肿瘤发生发展中的作用及其表达产物与肿瘤预后的关系,已经在很多肿瘤的研究中被证实。

Purpose: The present study probes to access the effect on the proliferation and cytotoxicity of the tumor infiltrating lymphocytes induced by interleukin-12 and activated by dendritic cells loaded with tumor antigen and to evaluate the possibility that IL-12 and DC enhance the specific cytotoxic activity of TILs to tumor cells.

目的:研究白介素12(IL-12)和负载肿瘤抗原的树突状细胞对肝癌肿瘤浸润淋巴细胞的增殖和细胞毒作用的影响,探讨IL-12和DC增强TIL特异性杀伤肿瘤细胞的可能性。

The results also showed that moxibustion serum could significantly enhance the susceptibility of tumor cells to lysis by Cytotoxicity T Lymphocytes in TILs in vitro, promote target distribution, raise activity of T cell clones which shows specific lysis to allogeneic tumor cells.

艾灸血清能明显提高指数生长期TIL中CTL的杀伤活性,提高CTL的靶向分布,增强对同种异体肿瘤特异性杀伤的T细胞克隆的活性,表现对同种异体肿瘤细胞较强的杀伤活性,而对异种肿瘤细胞低杀伤活性或不杀伤。

Immunohistochemical analysis for CD3, CD4, CD8, CD20, CD56, Fas and FasLwas performed, and the types and distribution of TILs in the three kinds of tumorswas measured.

采用免疫组织化学染色,检测三种肿瘤组织中CD3、CD4、CD8、CD20和CD56的表达,分析三种肿瘤中TILs的种类和分布特点;并检测三种肿瘤组织中Fas和FasL的表达; 3。

However, the study about the relationship between the number of TILs and non-small-cell lung cancer is very few, especially between CD4~+、 CD8~+T lymphocytes and NSCLC.

研究发现某些肿瘤(如,食道癌、胰腺癌、结肠直肠癌)浸润淋巴细胞(tumor infiltrating lymphocyte,TIL)的数量和T细胞亚群与肿瘤的预后有明显的关系,但肿瘤浸润淋巴细胞,特别是CD4~+、CD8~+T细胞亚群与非小细胞肺癌(non-small-cell lung cancer,NSCLC)预后的研究很少,说法不一。

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