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肿瘤

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In intravesical radioimmunoimaging T/NT value provided a new means for determining the extent of malignant bladder tumor. It may be useful for the early diagnosis, the choice of treatment and evaluation of prognosis in bladder cancer.

在膀胱癌RII中,通过定量方法判断诊断结果可提高对较小肿瘤的诊断灵敏度,可判断膀胱肿瘤的恶性程度,有助于肿瘤的早期诊断和治疗方案的选择及预后的评价。

MTT assay indicated that anti-proliferative activities in HeLa, SHIN3, HOAC-21 and HAC-2 cell lines were closely related to structure, 1,10-seco of eudesmane sesquiterpene lactone resulted in reduced anti-proliferative activity. The anti-tumor activity of isoalantolactone was probably achieved by inducing HeLa cell apoptosis.

提示A-环开环可能是导致桉叶烷型倍半萜内酯的体外抑制肿瘤细胞增殖作用消失或减弱的原因;异土木香内酯抑制肿瘤细胞增殖作用有可能是通过诱导肿瘤细胞凋亡机制而实现的。

The drug concentration in the janitrix and the abdoninal cavity is higher than that in the abdoninal aorta and peripheral venous after the treatment.The tissue of liver is about the same to kidney .The durg concentration in the janitrix and tissues is high and invariant for a long time. TACE and sequential chemotherapy inhibit the development of the cancer synergily and the latter cannot induce the toxic reaction.

化疗药物腹腔给药后门静脉血中,腹腔液中药物浓度显著高于腹主动脉,外周静脉血;腹腔给药后,肝组织中药物浓度高于肾组织;药物在门静脉,组织中存在较高的药物浓度,递减缓慢,浓度恒定,维持时间长;肝动脉化疗栓塞术有效地控制了肿瘤的大小,序贯化疗亦有效地抑制了肿瘤的发展和转移,两者间作用相互协同;序贯化疗不增加肿瘤病人的化疗毒副反应。

All tumors were histologically high grade (6 grade III and 10 grade IV). Three tumors showed heterologous elements, 2 osseous, and 1 rhabdomyoblastic. More often scattered than diffuse, S-100 protein staining was noted in 11 of 16 tumors and variable collagen IV staining in 10 of the 16. Immunoreactivity for p53 protein was diffuse and strong in 7 of 11 tumors. Twelve patients died within 17 months to 3 years of diagnosis, 1 was lost to follow-up, 2 are very recent cases, and 2 patients are currently alive, 1 after 2 recurrences, and another with spinal leptomeningeal metastases.

所有病例在组织学上都是高级别(6例III级和10例IV级)。3例肿瘤含有其他成分:2例含骨和1例含 rhabdomyoblastic.S-100蛋白染色显色于16例肿瘤中的11例,IV型胶原染色显色于16例中的10例,这些染色通常分散而不弥散。11例肿瘤中7例的p53蛋白免疫反应弥散且强烈。12例病人死于确诊后的17个月至3年,1例随访失败,2例是最近的病例,还有2例现在还活着,其中1例复发,另1例发生脊髓脑膜转移。

Follow-up (10 patients) showed 7 dead of disease, 1 alive with disease, and 2 disease free. Four atypical lipomatous tumors were seen including 2 with low-grade dedifferentiation.

随访了10例,7例死于此肿瘤、1例伴病存活、2例无再发存活。4例肿瘤为非典型脂肪肿瘤,其中2例伴低级别的去分化成分。

The method is highly sensitie, he says: as few as fie percent of the cells within the tumor mass needed to be induced into the lytic cycle in order to be detected.

这个方法的敏感性很高,他还说,在肿瘤中只要有5%的肿瘤细胞能被诱导转入溶解期,这个方法就能检测出肿瘤来。

Objective To analyze the CT and MRI manifestations of oral carcinoma,and to evaluate the value of imaging technologies in the diagnosis of oral carcinoma,thus to explore the most reasonable imaging method Methods 46 cases with oral carcinoma,proved by surgery and pathology (2 lip tumors,8 carcinomas of the gingival ridge,5 carcinomas of the buccal mucosa,24 tongue carcinomas,5 carcinomas of the floor of the mouth,2 tumors of the hard palate),were analysed retrospectively32 cases were examined with CT and 14 cases with MRIImaging presentations were compared with surgery and pathology Results Of the 46 cases with oral carcinoma,22 were ulcerative lesion of infiltrative growth,24 were masslike lesion of extruded trowthOf the 32 cases examined with CT scan,27 were detected,5 were missed,the 4 missed cases were confirmed to be superficial ulcers by surgery and pathologyOf the 10 cases with bone destruction examined with CT scan,8 were manifested,2 were missedAnd of the 14 cases with MRI scan,all 14 were detected Conclusion CT and MRI scan are valuable for diagnosis of oral carcinomasThey can manifest the morphology and size of primary tumor,contiguous structures,bone invasion and cervical lymph node metastasisMRI is the optimal imaging method for superficial ulcerative lesion of infiltratibe growth

徐 锋,罗德红,唐威,欧阳汉,周纯武目的分析口腔癌的CT及MRI表现,评价影像检查在口腔癌诊断中的应用价值,探索合理的影像学检查方法。方法回顾性分析经手术及病理证实的口腔癌46例(唇癌2例,牙龈癌8例,颊黏膜癌5例,舌癌24例,口底癌5例,硬腭癌2例),其中32例行CT扫描,14例行MRI扫描,将影像表现与手术所见及病理结果进行对照分析。结果 46例口腔癌中,呈浸润性生长的溃疡型病变22例,外生性生长的肿物型病变24例。CT扫描32例,明确显示病变27例,遗漏病变5例,其中4例为表浅溃疡型病变。CT扫描病例中,10例有骨质侵犯,CT扫描准确评价8例,遗漏2例。MRI扫描14例,均准确评价肿瘤及其与周围结构的关系。结论 CT、MRI对口腔癌原发肿瘤的形态、大小、周围结构侵犯、颈部淋巴结转移的评价有重要价值。对于较小及呈浸润性生长的表浅溃疡型肿瘤,CT扫描尤其是CT平扫难以准确显示,应首选MRI。

Results: Small intestinal tumors with gastrointestinal bleeding had the following clinical characteristics:(1) Melena was more common;(2) Most of the patients were over 40 years old;(3) Benign tumors were more common;(4) Smooth muscle tumors is more common in the benign tumors which majouryly located injijunam.

结果 :以消化道出血为主要症状的原发性小肠肿瘤的临床特点:(1)以便血为主;(2 )大多数在 4 0岁以上;(3)以良性肿瘤为多见;(4)良性肿瘤多为平滑肌肿瘤,主要位于空肠,而恶性肿瘤多位于回肠,以淋巴瘤和腺癌多见;(5 )消化道出血的时间和出血量与肿瘤的大小、性质无关。

Metanephric adenoma is a renal benign tumor, Mastering the clinical features and histopatho...

后肾腺瘤是一种罕见的肾脏原发上皮源性肿瘤,了解该肿瘤临床及病理特点有助于鉴别其他易于混淆的肿瘤类型。

Microscopically,tumors were composed of benign small and cuboidual epithelial cells and with scant cytoplasm.Immunohistochemially,with WT1, CD57,CK7,AE1,CD56 can help diagnosing metanephric adenoma.

结果:巨检肿瘤境界清楚;镜下该肿瘤由大小一致的肿瘤细胞排列成密集小管状、腺样结构,细胞无明显异型;文献报告WT1,CD57,CK7,AE1,CD56等抗体有助于鉴别诊断;后肾腺瘤预后较好。

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