肿瘤

Tumor excision was performed using ultrasonic shears, maintaining an adequate parenchymal margin. Bleeding from the tumor bed was controlled by bipolar diathermy . The renal artery was occluded when necessary. The edges of the renal parenchyma were approximately with 4 to 6, 2-zero absorbable sutures over hemostatic mesh.

超声刀沿瘤体边缘外0.5厘米处分离，由浅入深，边切割边止血，直到完全切除肿瘤，如切除肿瘤过程中肾脏创面出血过多影响操作，可暂时阻断肾动脉并计时，迅速切除肿瘤，双极电凝止血后，即可开放肾动脉。

The HL60 cells were inoculatedsubcutaneously to nude mice and after the dimeter of tumorreached 5mm,the NIH3T3-IFN-〓 cells were implanted i.p.intothe tumor-bearing mice or DOX was injected i.p.into the tumor-bearing mice.

将HL60细胞皮下接种BALB/C裸鼠体内，至皮下肿瘤长至直径达5mm时，给荷瘤小鼠腹腔内埋植〓细胞或腹腔注射阿霉素，结果发现其皮下肿瘤生长被显著抑制，特别是当NIH 3T3-IFN-〓细胞与阿霉素联合应用时，肿瘤生长抑制作用最明显。

According to the editorialist, the idea for studies such as this one exploring the possibility that tumor growth is driven by pluripotent cells considered cancer stem cells comes from work in the hematologic cancers, where stem-cell research is well established.

根据编辑评论，本研究的想法之一为肿瘤生长的可能性是受多潜能干细胞驱动，认为癌症干细胞是来自血液方面癌症，这方面的干细胞研究已经有一定成果；Massague医师指出，在肿瘤出现这一类的干细胞是十分有趣的，特别是这些肿瘤存在少数结果却是最阻抗治疗的。

Five models were used to investigate the "Changdong"" s anti-tumor effect: mice S180 sarcoma solid model, mice liver cancer H22 solid model, mice Lewis lung cancer model, as well as human liver cancer QGY and colon cancer LOVO implanted in naked mice; mice liver cancer H22 was also used to evaluate the enhancive effect of "Changdong" when it was co-applied with other anti-tumor agent or with radiotherapy; The "Changdong"" s cytotoxic effect in vitro on such tumors as QGY, LOVO, lung cancer A549, breast cancer MCF-7, as well as mice leukemia P388 was observed through MTT method. And investigate the effect of "Changdong" on proliferation of spleen lymphocyte, on activity of NK cell and on synthesis of IL-2 in mice bearing Lewis lung cancer, respectively. With propidium iodide straining, cell aigptosis and cell circle were analyzed by flow cytometry. Result:"Changdong" has an evident tumor inhibitive effect on mice tumor model as well as human tumor implanted in naked mice with a quantity-effect relationship.

使用小鼠S180肉瘤、小鼠肝癌H22实体瘤和小鼠Lewis肺癌模型，以及人体肝癌QGY和人体肠癌LOVO裸鼠异种移植模型，进行"长动"的抗肿瘤药效学研究：用小鼠肝癌H22进行"长动"合并放疗和化疗的增效作用研究；用MTT法进行"长动"对肝癌QGY、肠癌LOVO、肺癌A549、乳腺癌MCF-7、小鼠白血病P388等10株人体和动物肿瘤细胞的体外细胞毒性作用研究；用淋巴细胞转化试验、小鼠NK细胞活性试验、小鼠胸腺细胞增殖法分别测定"长动"对荷Lewis肺癌小鼠的脾淋巴细胞增殖的影响、自然杀伤细胞活性的影响和对小鼠产生白介素-2(IL-2)的影响；用流式细胞仪PI单染色法进行"长动"对人体肝癌QGY细胞的体外诱导凋亡作用和对肿瘤细胞周期的影响的研究。

This study that observed the expression and distribution of 4 apoptotic factors, relation apoptotic factor with apoptosis, changes of T and B subgroup, and changes of molecular pathology in 14 cows suffering from enzootic bovine leucosis from several resides was detected by histochemistry, TUNEL technology, immune-fluorescent flow cytometry and so on. The aim of this experiment supplies theoretic basis for preventive and therapy of EBL, and consult dates for T lymphoid cell leucosis of human being .

本研究检查并剖检了14例临床与实验室诊断为EBL的病牛，观察分析了肿瘤发生的情况和特征，采用免疫组织化学ABC法、原位末端标记TUNEL技术和免疫荧光流式细胞检测法等技术，从EBL肿瘤细胞凋亡特性入手，围绕4种凋亡因子和几种免疫相关因子与EBL肿瘤发生的关系及其在诊治方面的应用进行了首次有价值的探索，其目的在于为防治EBL提供科学的理论依据，同时，也将为人类T细胞白血病Ⅰ。

Result:This example main clinical manifestation for the abdominal pain, the platoon is black then, epigastrium CT, the magnetic resonance and the gastroscopy prompt the duodenum tumor, the good duodenum tumor excision method, after the technique the pathology inspection shows the duodenum fusiform shape cell lump, the immunity group result shows tumor cell CD117, CD34, the union protein, the S-100 protein, the muscle moves the protein, finally diagnoses for the duodenum benignity the nature lump.

结果：该例主要临床表现为腹痛、排黑便，上腹部CT、磁共振和胃镜检查均提示十二指肠肿瘤，行十二指肠肿瘤切除术，术后病理检查示十二指肠梭形细胞瘤，免疫组化结果示肿瘤细胞CD117，CD34，结合蛋白，S-100蛋白，肌动蛋白，最后确诊为十二指肠良性间质瘤。

In conclusion, our results demonstrated that intratumoral electroporation-mediated IL-6 and IL-15 gene therapy for canine transmissible venereal tumor in the canine model efficiently tumor escape mechanism and also intensified the host immune responses.

以上这些结果显示使用肿瘤内电冲，进行IL-6与IL-15基因治疗，在实验犬模式，可成功破坏肿瘤逃避免疫系统的作用并提升免疫反应，达到成功治疗肿瘤之目的。

objective to study the anti-tumor activity and enhancing immune effect of phellinus linteus.methods the anti-tumor activity of phellinus linteus was estimated by the longevity of eac mice,the immune effect of tumorous mice was tested by the experiment of carbon particle expurgation and the il-2 concentration in serum of tumorous mice was determined by elisa.results phellinus linteus can prolong eac mouse's life and can increase the il-2 concentration in serum of tumorous mouse but can't affect the immune effect of tumorous mouse.conclusion chinese hurb phellinus linteus possess some antitumor power for tumor-loaded mice,but further research is needed.

目的 观察桑黄对肿瘤的抑制作用及对机体免疫功能的影响。方法以小鼠艾氏腹水癌的生命延长率评价桑黄的抗肿瘤作用，以炭末廓清实验观察荷瘤小鼠非特异性免疫功能，以elisa法测定荷瘤小鼠血清il-2浓度。结果桑黄对eac荷瘤小鼠的生存时间有延长作用，对荷瘤小鼠血清il-2浓度有提高作用，对荷瘤小鼠非特异性免疫功能无明显影响。结论中药桑黄对荷瘤小鼠具有一定的抗肿瘤能力，作用的强度和作用机制的深度还有待进一步研究。

Animal tumor models were established by injecting Meth A fibrosarcoma cells or Colon Tumor 26 (CT 26) cells into the tight of BALB/c mice.

肿瘤模型选用的是Meth A纤维肉瘤BALB／c小鼠肿瘤模型和CT 26结肠癌BALB／c小鼠肿瘤模型。

Here we showed that EMT was inhibited by resveratrol through down-regulating the expression of FOXC2 (forkhead box C2), a critical transcription factor involved in EMT transition.

目前的研究显示上皮-间质转化对多种肿瘤的发展进程具有重要的影响，上皮-间质转化可促近肿瘤细胞的浸润以及肿瘤的转移，在人类以及动物实验中发现上皮-间质转化会导致预后不良。

Do you know, i need you to come back

你知道吗，我需要你回来

Yang yinshu、Wang xiangsheng、Li decang,The first discovery of haemaphysalis conicinna.

1〕 杨银书，王祥生，李德昌。安徽省首次发现嗜群血蜱。