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baric trajectorywith lithotripsy ureteroscopy can treat colic or functionfailure by ureteral calculi in emergency treatment.it is a simple、safety、efficient method to treat colic or functionfailure by ureteral calculiin emergency treatment.

急诊行行输尿管镜气压弹道碎石术治疗输尿管下段结石,可在短时间内缓解肾绞痛,及时解除孤立肾急性梗阻性肾功能衰竭,是简单省时、安全有效、在短时间内解除患者痛苦及挽救肾功能的有效方法。

We also have observed some organs pathological changes of juvenile Jian Carp, such as pancreas acinous gland and zymogen granules of acinous gland cell disappearing, intercellular substance hyperplasia and inflammatory cells soakage, hepatatrophia, liver cell granular or vacuolar degeneration and necrosis, karyolysis or pyknosis, glycogen granules decreasing, metanephros atrophy, metanephric canaliculus epithelium granular or vacuolar degeneration and necrosis, mitochondrion swelling and mitochondrion cristae disappearing, karyolysis, distal convolutal tubule microvilli desquamating, spleen marrow cell degeneration and necrosis, intercellular substance of spleen hyperplasia, spleen atresia, blood corpuscle disappearing.

后肾土黄色、淡褐色或苍白色,肾小管上皮细胞肿胀、颗粒或水泡变性、坏死,细胞内有大量血细胞流出,线粒体肿胀,嵴结构消失,细胞核溶解,肾间质甲状腺滤泡和拟淋巴细胞增生,远曲小管微绒毛脱落、管道细胞界限不清。心脏肌纤维肿胀、颗粒或空泡变性,严重的肌纤维溶解、变细或断裂,肌纤维间水肿、炎性细胞浸润,部分心肌细胞核浓缩。脾脏暗褐色,脾髓质细胞变性、坏死,拟淋巴细胞明显减少,淋巴细胞岛少见、岛中细胞成份减少,黑素巨噬细胞中心减少、体积缩小,脾脏网状基质水肿,脾窦闭锁,血细胞减少。

Methods Immunohistochemistry of streptavidin-perosidase method was applied in the observation of the expression of TIAF-1 in each group, including tissues obtained from the unaffected part of nephrectomized kidneys with renal cell carcinoma (n=6) and cadaveric donor of normal kidneys (n=8) as the control group, tissues with acute rejection (AR, n=16) and those with chronic rejection (CR, n=28), and in the analysis combined with the number of positive cells of CD3, CD20 and CD68 infiltrated in the interstitium.

采用SP免疫组织化学染色法对6例因肾细胞癌行肾切除的未受肿瘤侵犯的正常肾组织和8例供肾正常肾组织、16例急性排斥反应和28例慢性排斥反应移植肾组织中TIAF-1的表达进行观察,并对间质浸润细胞中CD3、CD20、CD68阳性细胞数进行分析。

Demonstrative green tea can reduce gland purine to be damaged to the qualitative pathology between bandicoot kidney, green tea has fight the action that qualitative fiber changes between kidney, and can restrain hyperplasia of fibrous of I,Ⅲ collagen, this may be green tea qualitative fiber is changed between kidney of prevention and cure, one of mechanisms that defer chronic kidney failure to develop a process.

说明绿茶能够减轻腺嘌呤对大鼠肾间质的病理损害,绿茶有抗肾间质纤维化的功能,并且能抑制I、Ⅲ型胶原纤维的增生,这可能是绿茶防治肾间质纤维化、延缓慢性肾衰竭发展进程的机制之一。

To observe the changes of pathology and contents of hydroxyproline, total antioxidizing capability, total superoxide dismutase and malondialdehyde in kidneys of unilateral ureteral obstruction rats, and investigate the function of oxidation stress reaction in renal interstitial fibrosis.

目的 采用单侧输尿管结扎致肾间质纤维化大鼠模型,观察UUO后肾脏病理和肾组织在羟氨酸含量及各氧化应激指标的改变,探讨氧化应激在肾间质纤维化中的作用。

Hematocrit and blood viscosity at shear rate in 150/s, 30/s, 5/s, 1/s, renal fibrosis serum markers, serum creatinine and blood urea nitrogen were detected respectively in sham operation and model group; microcirculation microscope was used to observe the thread of hypoglottis and auricle in rats.

建立单侧输尿管梗阻致大鼠肾间质纤维化模型,观察肾间质纤维化大鼠全血粘度150/s切变率、30/s切变率、5/s切变率、1/s切变率、红细胞压积、舌下及耳廓的脉络变化,同时检测肾纤维化指标、血清肌酐及尿素氮。

Intrarenal CRP level but not serum CRP is closely associated with TIF in chronic CsA nephrotoxicity.

本研究通过检测大鼠血CRP水平,探讨了其与慢性CsA肾毒性肾小管间质纤维化间的关系。

BSA can induce ACE up-regulation in proximal tubular cells, which may lead to the increased production of local AngⅡ and finally contributes to the intrarenal activation of renin angiotensin system.

BSA可显著增加HK-2细胞ACE表达,此作用可能是导致肾间质局部AngⅡ蓄积从而启动肾小管间质纤维化的重要机制之一。

Objective: To explore the effect and happening mechanism of hdrochloric acid kukoline for the treatment of renal interstitial fibrosis,to supply some according for clinic how to resist glomeruli and nephric tubule interstitial fibrosis.

目的:探讨盐酸青藤碱在治疗肾间质性纤维化中的作用及其发生机制,为临床如何阻止、防止肾小球和肾小管间质纤维硬化提供借鉴。

The granule could significantly ameliorate mesenchymal deposit of collagenⅠ,Ⅲ,Ⅳ and α-SMA due to ureter ligation in rats with UUO, lower hyperexpression of TGF-β1 mRNA and TIMP-1 mRNA after renal injury, decrease the number of cells infiltrating into renal mesenchyma.

在单侧输尿管结扎大鼠中补肾生血颗粒剂能明显改善输尿管结扎所致的Ⅰ、Ⅲ、Ⅳ型胶原和α-SMA在肾间质中的沉积,降低肾脏损伤后亢进的TGF-β1 mRNA和TIMP-1 mRNA的水平;减少肾间质中浸润的〓T淋巴细胞数目。

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