肾脏学

I am a board ... certified diagnostician with a double specialty of infectious disease and nephrology.

我是董事会……我是有证书的诊断专家，有着传染病和肾脏学的双料学位。

This is the website of the Journal of Renal Nutrition, which is devoted exclusively to renal nutrition science and renal dietetics.

这是《肾脏营养学期刊》的网站，该杂志致力于肾脏营养学科学和肾脏饮食学研究。

Results (1) 6 cases of Tuberous Sclerosis. Diffused subependymal nodular calcification lesions were found in all cases on unenhenced CT. 4 patients are 2 pairs of mother/child relationship. Both of the two mothers are found to suffer from renal angiomyolipoma.(2)1 case of neurofibromatosis showed abnormal spinal canal: scoliosis of thoracic and lumbar spine, concave change of vertebral posterior border. Bilateral renal hypogenesis was found in this patient. Diffused hyper-density lesions were found in kidney and fatty accumulation was found in back skin.(3)6 cases of Sturge-Weber syndrome. On unenhenced CT, curving and strip-shaped calcifications were found along the parietal and occipital gyrus.

结果 ①结节性硬化6例，所有病例CT平扫见两侧脑室室管膜下多发小结节状高密度钙化灶，其中4例为两对母子关系，并见两位母亲合并有肾脏错构瘤，；②神经纤维瘤病1例，MRI表现为椎管异常，胸腰段脊柱侧弯，椎体后缘呈明显的切凹改变；伴有双肾发育不良，CT示肾内多个高密度影，背部皮肤多量脂肪堆积，③脑颜面血管瘤综合征6例， CT可见顶枕部沿脑回分布的弯曲的条状高密度钙化，部分延伸致侧脑室内，增强后见病灶内有扭曲的条状和结节状明显强化的血管影；④小脑血管瘤病4例，影像学表现为小脑内大囊、小结节样占位性病变。

It can be said thatblood stasis is the main pathology of DN,which is in line with Chinese medicine in "invalidism must accompany with blood stagnation""invalidism develop into collaterals" The view of blood stasis also match the modern medical point of hemodynamics changes and capillaries disease in patients with DN,such as increased hemorheology general index,blood viscosity and lipids, reduced kidney blood flow,platelet aggregation,sclerosis of blood vessels, renal microcirculation disturbance,even hypercoagulability.

可以说，瘀血阻络是糖尿病肾病的主要病机，这既符合于中医"久病必瘀""久病入络"的学术观点，也与现代医学认识的糖尿病肾病患者血液动力学和肾脏微血管病理学实验中，血液流变学的指数普遍升高、血浆粘度增加、血脂增高、肾血流量减少，血小板聚集、血管硬化，肾微循环障碍，甚至出现高凝状态的研究相当吻合。

The connective tissue is little and the borderline of hepatic lobule is mistiness in liver.

采用常规石蜡切片对安南龟的肝脏和肾脏进行了组织学观察。

However, at least 1 outside observer urged caution in interpreting these findings."The reliability and validity of high-resolution computerized tomography in kidney failure has been questioned," Ell Friedman, MD, nephrologist and Distinguished Teaching Professor of Medicine at the State University of New York Downstate Medical Center in Brooklyn, told Medscape Nephrology . He cited a recent study by Barraclough et al ( Nephrol Dial Transplant . Published online before print May 1, 2008) showing significant imprecision in HRCT-derived validation of coronary calcification in kidney failure patients, depending on who reads the results.

然而，至少一位以上的外部观察者表示在阐释这些研究发现时必须特别小心，布鲁克林纽约州立大学Downstate医学中心的肾脏学家与卓越教学医学教授Ell Friedman医师向Medscape肾脏学表示，高解析度电脑断层扫描应用於肾脏衰竭上的信度与效度已经受到质疑；他引用最近一项由Barraclough等人（发表於Nephrol Dial Transplant，於2008年5月1日线上发表）的研究结果，显示HRCT延伸的肾脏衰竭病患冠状动脉钙化检验有相当程度的误差，取决於谁判读检验结果。

Result There were 70 of paraplegia patients, including 39 of hypertension and 31 of non-hypertension.

1.2.2肾脏损害的诊断标准[3]：肾脏结构和功能的异常，伴或不伴肾小球滤过率的降低，观察指标包括尿或血液组分的异常，或影像学的检查的异常，蛋白尿是肾脏损害的独立观测指标。

Andrezj Wiececk, MD, who cochaired the session at which these data were presented, noted that there was no mention of the criteria used to define LT."I think this is fundamental, because then you can select patients for long-term protocols," said Dr. Wiecek, head of the Department of Nephrology, Endocrinology, and Metabolic Diseases at Silesian University School of Medicine in Katowice, Poland. He was not involved in the study.

发表会中的共同主持人Andrezj Wiececk医师表示，该研究中并未提到LT的条件；波兰Katowice Silesian大学医学院肾脏学、内分泌学与代谢疾病科主任Wiececk医师表示，我认为这是很基本的，因为接著你可以选择进行长期研究的病患；他并未参与这项研究。

The findings of the newly identified goose paramyxovirus strain GPMV/HBexperimental infection were as follows: The challenge caused high morbidity and highmortality.The clinical signs included severe depression, decreased appetite or anorexia,white,yellow and green diarrhea, with neural symptoms;pathological changes showed thathaemorrhage and ulceration of intestine mucosa, necrosis of spleen and pancreas,andedema of liver and kidney, uratic deposition in kidney.Eosinophilic inclusion bodies werefound in the cytoplasm of pancreas and a large quantities of fiber protein were found inintestine. Lots of hemosidefin was found in some area of liver and kidney. A number ofT、B lymphocytes reduced sharply in spleen,lymph nodes in dead geese. Transmissionalelectron microscope showed that some cells had the morphological characteristics ofmitochondria swelling, morphological changes were condensation of nuclear chromatininto dense masses,followed by its marginating against the nuclear envelope, andespecially concentration of cytoplasm association with lots of lipid droplet.

人工感染雏鹅实验中，雏鹅临床表现为高发病率和高死亡率，食欲和饮水减少，拉白色、黄绿色稀粪，伴有神经症状；常规组织学观察，脾脏和胰腺肿大，有白色坏死斑点，肠道出血和坏死，肝脏肿大变性，肾脏肿大变性有尿酸盐沉着等；用特殊染色和组织化学方法首次对人工感染鹅副粘病毒的雏鹅的重要脏器进行研究，结果表明：胰腺中发现病毒包涵体，肠道中大量纤维素以及胶原纤维增生，肾脏、肺脏大量含铁血黄素沉着，免疫器官如脾脏和淋巴结中T、B淋巴细胞大量减少；电镜下多种细胞呈现线粒体水肿，多种实质细胞的染色质固缩，染色质边集，特别是细胞内容物如脂肪滴增多的病理变化特征。

The results summarized as follows:(1)The main pharmacokinetic parameters Tmax was about 2h, Cmax was 8.365, 7.519, 1.871, 6.485, 4.060μg/mL in blood, gill, kidney, liver, and muscle respectively, after oral administration at a dose of 30 mg/kg; while t1/2 were 8.180~23.249h. These showed that the NFLX absorption was rapid after oral administration of NFLX in Scophthalmus maximus, but the residence time in the fish was long.(2) T1/2 were 74.88~200.45h after oral administration at dose of 30 mg/kg for five consecutive days, which showed that the attenuation of NFLX in the fish body was slow and the residue concentration in the kidney was the highest.

另外，本文测定了大菱鲆成鱼体内NFLX的药物浓度，用MCP-KP药动学程序对所得的药物浓度-时间数据进行分析，结果表明：1单次混饲口灌(30 mg/kg体重日)NFLX，药物在大菱鲆体内的达峰时间为2h，血液、腮、肾脏、肝脏、肌肉达峰浓度分别为：8.365、7.519、1.871、6.485、4.060μg/mL，消除半衰期为8.180～23.249h，说明NFLX在大菱鲆体内吸收较迅速，但滞留时间较长。2连续五天混饲口灌(30 mg/kg体重日)NFLX，消除半衰期为74.88～200.45h，说明混饲口灌NFLX在大菱鲆体内消除缓慢，其中以肾脏中残留最显著。

With Death guitarist Schuldiner adopting vocal duties, the band made a major impact on the scene.

随着死亡的吉他手Schuldiner接受主唱的职务，乐队在现实中树立了重要的影响。

But he could still end up breakfasting on Swiss-government issue muesli because all six are accused of nicking around 45 million pounds they should have paid to FIFA.

不过他最后仍有可能沦为瑞士政府&议事餐桌&上的一道早餐，因为这所有六个人都被指控把本应支付给国际足联的大约4500万英镑骗了个精光。