肾脏

Objective: Chronic renal failure is damage to kidney which is caused by various kinds of idiopathic or successive renal disease. Half-backed renal function leads to a series of clinical symptoms which are caused by decompensate. The renal pathological changes develops slowly but it is one-way and irrecoverable. It evolves as terminal renal disease at last. The pathogenesis of CRF can be unpuzzled with the theory of Chinese medical that it is correlated with asthenia, turbid, and stagnancy.

目的： 慢性肾功能衰竭是由各种原发或继发性肾脏疾患导致肾单位破坏，肾脏功能发生障碍引起的一系列症状和代谢紊乱，虽进展缓慢，但其病程单向不可逆，而且在病程某一阶段呈进行性发展或加重，最终发展为终末期肾病。

The prognosis depends on the cause, site, duration, and degree of kidney damage and renal decompensation.

预后取决于原因，位置，病程及肾脏损害和肾脏失偿程度。

The levels of serum creatinine,Malon dialdehyde and activity of superoxide dismutase in kidney tissue were determined. The kidney tissue was examined under light microscopy.

于再灌注6 h、12 h、24 h各组分别随机选取10只大鼠进行标本检测：观察动物肾脏组织病理切片；测量肾脏组织中脂质过氧化产物丙二醛和超氧化物歧化酶的含量。

The present investigation was undertaken to observe the renal response to the distention of the urinary bladder and to elucidate the mechanism by which the effect takes place.

本实验是在狗的急性实验中观察膀胱加压对肾脏泌尿影响的机制，结果表明：膀胱加压可反射地抑制肾脏泌尿，抑制持续的时间一般为30—60分钟。

Many studies has suggested UII involves physiologic adjustment of normal kidney and may have a role in many kidney diseases such as dropsical nephritis,diabetic nephropathy and tumor of kidney.

目前许多研究发现UII参与正常肾脏的生理调节机制并在多种肾脏疾病如肾病综合征、糖尿病肾病和肾肿瘤等中起作用。

It can control and reduce blood sugar content and kidney hypertrophy symptom, reduce kidney index and ruduce the egest amount of urine album of diabetes patient.

它可以有效地控制或降低糖尿病大鼠的血糖量，能控制或减轻肾脏肥大的症状，能明显地降低肾脏指数。它能明显降低糖尿病患者尿白蛋白的排泄量。

Not only effect of Zhixiaotongmaining on DM at earlier stage,effects of the content change of NO and endotheliolysin on the formation of hypernephrotrophy and high filtration were also studied.

DM早期肾脏突出的病理生理改变为肾脏肥大和肾小球高滤过，这种改变是DM后期肾小球硬化的一个主要形成原因。

Both accumulation of ROS and reduction of GSH-PX have relation with diabetic renal dysfunction, which also causing execration increase of urine MCP-1. ROS via inflammation reaction can damage diabetic renal function.

ROS合成增加、GSH-PX的活性下降均参与了糖尿病肾脏的损伤，并使代表肾脏炎症反应的尿MCP-1随尿排出增加，推测ROS介导的炎性反应在糖尿病肾病的发生、发展中发挥了作用。

Objective: The purpose of our studies are gaining a better insight into the effect of genistein on mesangial cell"s phenotype change and ECM expression plus degradation under DN circumstances.We add genistein with different concentrations in high glucose cultured rat mesangial cells;feed DM rats with the single concentration genistein for different days;to explore the expression of SMemb,the mark of mesangial cell"s hypertrophy phenotype change;to examine the synthesis of Fn as well as the change of the balance between MMP-2 and TIMP-l;to comprehend its effect on renal pathological changes of DM rats and some related factors;trying toexplore the possible mechanisms.Through these studies,we will have some information about the experimental value of genistein in DN field.

目的：为了研究金雀异黄素对DN环境下大鼠MC肥大表型转换标志物SMemb和ECM分泌及降解的影响，我们拟在细胞水平以不同浓度的金雀异黄素作用于高糖培养下大鼠MC，在动物水平以同一浓度的金雀异黄素作用于DM大鼠不同时间，观察细胞表型转换标志物SMemb、ECM主要成分Fn、ECM降解酶系统基质金属蛋白酶—2(MMP-2)／基质金属蛋白酶抑制剂—1(TIMP-1)表达的变化，同时观察金雀异黄素对DM大鼠肾脏病理及影响肾脏病进展的糖脂代谢紊乱的影响，并进一步探讨金雀异黄素发挥作用的可能机制；为明确金雀异黄素在DN治疗中的地位及意义提供实验依据。

The above results suggested that the mechanism of FM action may be through enhancing the level of NO in kidney, and increasing kidney blood flow and the percolation of kidney globule.

其作用机制之一可能是通过提高肾脏NO的合成，增加肾血流量和肾小球滤过率，从而减轻对肾脏的损害。

On the other hand, the more important thing is because the urban housing is a kind of heterogeneity products.

另一方面，更重要的是由于城市住房是一种异质性产品。

Climate histogram is the fall that collects place measure calm value, cent serves as cross axle for a few equal interval, the area that the frequency that the value appears according to place is accumulated and becomes will be determined inside each interval, discharge the graph that rise with post, also be called histogram.

气候直方图是将所收集的降水量测定值，分为几个相等的区间作为横轴，并将各区间内所测定值依所出现的次数累积而成的面积，用柱子排起来的图形，也叫做柱状图。