肾素

International Circulation: I'd like to talk about direct renin inhibition.

国际循环》：我想和您谈谈直接的肾素抑制剂方面的问题。

From a pharmacologist's point of view, the most appropriate place to block the system is at the rate-limiting step, which is where renin works.

从药理专家的观点来看，阻断这一系统的最恰当途径是作用于限速步骤，也就是对肾素直接进行阻断。

Transgenic mice carrying human renin gene were generated by means of pronucleus injection.

采用地高辛标记探针，建立了一种快速检测和筛选转人肾素基因小鼠的方法。

Objective To study the change of the ratio of plasma aldosterone and renin activity after 40mg furosemide intravenous injection in refractoriness hypertension and primary aldosteronism patients.

目的 比较顽固性高血压患者与原发性醛固酮增多症患者大剂量速尿静脉注射激发试验对血浆醛固酮／肾素比值的影响。

This structure is the site for renin production.

此结构是产生肾素的部位。

It is clear that aliskiren is the first available direct renin activity inhibitor to reduce blood pressure.

很明显，阿利克仑是第一个可以使用的用以降低血压的直接肾素活性抑制剂。

When we inhibit this direct renin activity, what are some of the clinical benefits or results of this inhibition?

当我们抑制这种直接肾素活性时，这种抑制的临床获益或者结果有哪些？

Plasma renin activity is usually normal in patients with primary hypertension but is suppressed in about 25% and elevated in about 15%.

原发性高血压病人的血浆肾素活性通常是正常的，但约25%受抑制，约15%可能升高。

Methods Using the method of giving rabbit abdomen aorta half ligations to build the chronic heart failure model to observe Qiliqiangxin capsule the effect to blood flow mechanics index,room wall thickness,heart exponent and heart ventricle reconstitution biochemistry index.

观察血流动力学、标志心室重构的室壁厚度及心脏指数及肾素―血管紧张素―醛固酮系统相关生化指标的变化。

It is very important to the preventions, diagnoses and treatments of diseases, especially the complicated ones.

近年来，国内外学者对妊高征的肾素-血管紧张素系统的相关基因进行了研究。

The labia have now been sutured together almost completely.The drains and the Foley catheter come out at the top.

此刻阴唇已经几乎完全的缝在一起了，排除多余淤血体液的管子和Foley导管从顶端冒出来。

To get the business done, I suggest we split the difference in price.

为了做成这笔生意，我建议我们在价格上大家各让一半。