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肾小球肾炎

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Methods: Separated 120 cases with glomerular diseases into chronic glomerular nephritis group (70 cases, including 33 cases with normal serum creatinine, 17 cases with azotemia, 20 cases with uremia, 33 cases accompanied with hypertension), acute nephritis group (12 cases), nephritic syndrome group (38 cases), and selected 30 healthy cases as control group. Detected concentration of NO in serum with nitrate reductase method, and made comparison among groups.

120例肾小球疾病患者分为慢性肾小球肾炎组(70例,其中血清肌酐正常33例,氮质血症17例,尿毒症20例,伴有高血压33例)、急性肾炎组(12例)、肾病综合征组(38例),同期选择30例健康体检者作为对照组,采用稍酸还原酶法测定肾小球疾病患者及对照组血浆NO浓度,并对各组NO浓度进行比较。

The principal active constituent of fleabane injection was anthoxanthin substance, which owned important clinical value. The paper summarized its applicative progress in treatment of chronic renal failure, dropsical nephritis, chronic glomerular nephritis, diabetic nephropathy, acute nephritis in recent years.

灯盏细辛注射液主要有效成份为黄酮物质,在临床中有重要应用价值,文章就其在近年来治疗慢性肾功能衰竭、肾病综合症、慢性肾小球肾炎、糖尿病肾病、急性肾炎中的应用作一综述。

The chronic Glomerulonephritis is an immune disease originated from the inflammation of glomerule, Its cause was unknown in most cases. Most cases are not transmitted acutely.

慢性肾小球肾炎是由多种原因引起的原发於肾小球的一组免疫性炎症性疾病。

The result showed, of 50 CGN patients, 29 cases were MsPGN, 11 cases IgAN, 4 cases MN, 3 cases MPGN, 1 case ML, FSGS and PSGN. The completely remittent rate is 32%, and the partly remittent rate is 54%. The total effective rate is 86%. The total effective rate of MsPGN and IgAN is 96. 35% and 90.91% respectively, which are superior to that (50%) of other types (p.01 and p.05). The result show.

结果50例CGN患者中有系膜增生性肾炎29例,IgA肾病11例,膜性肾病4例,膜增生性肾炎3例,肾小球轻微病变、局灶性节段性肾小球硬化症、增生性硬化性肾小球肾炎各1例。50例患者的临床疗效为完全缓解率32%,部分缓解率54%,总有效率86%;其中MsPGN和IgAN总有效率分别为96.35%和90.91%,明显优于总有效率为50%的其他病理类型(P.01和P.05)。

Crescentic glomerulonephritis is known as rapidly progressive glomerulonephritis because this disease is very progressive.

新月体性肾小球肾炎之所以被称为快速进行性肾小球肾炎是由于这种疾病的进展非常快。

Results Two males and one female aged 28 ~ 67 years suffered primary glomerulonephritis crescentic glomerulonephritis caused by microscopic polyangiitis, or lupus nephritis respectively.

结果 3例患者年龄为28~67岁,男性2例,女性1例。1例为原发性肾小球肾炎、1例为狼疮性肾炎、1例为显微镜下多血管炎致新月体肾炎。

In the renal biopsy specimens from patients with glomerular diseases, the expression of CD44 was obviously abnormal.

结果提示CD44在增殖性肾小球肾炎的发病及肾小球疾病的慢性进展中发挥作用。

Results In the 102 males,84 females,who are average 13~65(30.7±13) years old,there are 76(41%) cases of nephrotic syndrome,59(32%) cases of chronic glomerulonephritis,41(22%) cases of latent glomerulonephritis,10(5%) cases of acute nephritic syndrome.

结果 本组资料中男102例,女84例,年龄13~65岁,平均(30.7±13)岁,其中肾病综合征76例,慢性肾小球肾炎59例,隐匿性肾小球肾炎41例,急性肾炎综合征10例;所占比例分别为41%、32%、22%、5%。

And the most severe pathological change was shown in patients of Speen –kidney Yang Deficiency , all grade 3 renal interstitial fibrosis belonged to it.

1、BMP-7表达与慢性肾小球肾炎肾间质纤维化程度有密切关系,它可以作为慢性肾小球肾炎肾间质纤维化程度的标志。

It is possible that upregulation of acidic ribosomal protein P0 may be involved in the development of glomerulonephritis and glomerulosclerosis mediated by TGF-β1

酸性核糖体蛋白P0是一个与TGF-β1基因表达密切相关的基因,可能参与TGF-β1介导的肾小球肾炎和肾小球硬化的发生机制。

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