肾小球

objective to study the role of urinary albumin excretion rate and glomerular filtration rate for diagnosis of early diabetic nephropathy.

目的 探讨尿白蛋白排泄率和肾小球滤过率在早期糖尿病肾病的诊断价值。

Methods: Rat models of chronic renal failure were made by cut 5/6 kindney or fed with feedingstuff which contains adenine(0.75%) for 4 weeks. Experimental treatment was applied by giving Yi Shen Granule and the curative effect of Yi Shen Granule on ongoing pathological changes of CRF was studied. According to the data of CRF rats in weight, water wastage, hemanalysis(RBC、HGB、HCT、MCV、MCH), urinalysis(volume, specific gravity, pH, proteinuria), blood serum analysis(BUN、Cre、ALB、TP), kidney weight coefficient and kidney morphology ( the grade of expansile renal tubule and the diameter of glomerulus ),the pharmacological effect of Yi Shen Granule could be ascertained.

实验选用0.75%腺嘌呤饲喂法致大鼠慢性肾衰模型和5/6肾切除法致大鼠肾衰模型，考察益肾颗粒对慢性肾功能衰竭进行性病变的影响，以造模动物一般状况观察、血液学指标包括红细胞计数、血红蛋白、红细胞压积、平均红细胞体积、平均红细胞血红蛋白(RBC、HGB、HCT、MCV、MCH)，尿液指标(尿量、比重SG、pH值、尿蛋白)、血清生化学指标包括尿素氮、肌酐、白蛋白、总蛋白(BUN、Cre、ALB、TP)、脏器解剖和病理观察指标(肾小管扩张分级评分和肾小球径长)做为判定依据。

Rapamycin may extenuate the pathological damage of IgAN rats by inhibiting JAK/STAT signaling pathway, activation of STAT3 and mesangial proliferation.

雷帕霉素可能通过抑制IgA肾病大鼠肾小球JAK/STAT信号途径、直接抑制STAT3的活化以及抑制系膜细胞的增殖而减轻病变程度。

About 15% of glomerular filtration occurs through the mesangium , with the remainder through the fenestrated epithelium.

大约有15％通过肾小球膜滤过，而剩余的通过有孔的上皮滤过。

Objective To study the effect of serum contained fenugreek seeds polysaccharide A2 on extracellular matrix accumulation and connective tissue growth factor expression in rat mesangial cells.

目的 探讨胡芦巴多糖A2含药血清对大鼠肾小球系膜细胞细胞外基质沉积及结缔组织生长因子表达的影响。

The above results suggested that the mechanism of FM action may be through enhancing the level of NO in kidney, and increasing kidney blood flow and the percolation of kidney globule.

其作用机制之一可能是通过提高肾脏NO的合成，增加肾血流量和肾小球滤过率，从而减轻对肾脏的损害。

Renal morphological structures were showed: glomerule atrophy of KXLKL in rats with chronic renal failure and multiple interstitial connective tissues were significantly mitigated,which were close to normal.

肾组织形态可见：抗纤灵组肾衰大鼠肾小球萎缩明显减轻，机构较接近正常。

Results Eleven cases of TBMN in children were showed as isolated hematuria, glomerule with normal appearance or slight change and characterized by diffuse thin basement membrane in ultrastructural observation( the thickness of GBM＜ 200 nm, and dense-layer＜ 100 nm).

结果：11例小儿TBMN临床主要表现为单纯血尿，无其它明显的阳性体征，光镜下肾小球无明显改变或轻微异常，未见蛋白管型，包曼囊内及肾小管腔内可见渗出的红细胞，电镜下GBM广泛变薄，平均厚度＜200 nm，致密层厚度＜100 nm。

Results Supplementing Qi and nourishing Yin, clearing and promoting blood circulation traditional Chinese drug could decrease the excretion quantity of urine protein in minimal change nephropathy rats, improve serum biochemical indicator, lower TXB2 level in plasma and urine, raise 6 - keto- PGF 1α level in urine, improve hypercoagulabale state and repair glomerule epithelial cell foot process structure.

结果益气养阴、清利活血中药可减少微小痛变肾痛大鼠尿蛋白的排泄量，改善血清生化指标，降低血浆、尿液TXB2水平，提高尿液6-keto—PGF1α水平，改善高凝状态，修复肾小球上皮细胞足突的结构。

Urine red blood cell count, 24 hour urine protein quantitation, serum creatinine and blood urea nitrogen were examined, the renal morphological changes under microscopy and ultrastructure under electron microscope were observed. immunofluorescence was applied to unveal the immunological damag on glomerule of kidney.

以 sd 大鼠为实验动物，通过一侧肾切除，反复尾静脉注射葡萄球菌肠毒素 b 的方法，制作 iga 大鼠肾病肾小球硬化模型。1 周后，同时予以鬼箭羽水煎液灌胃治疗为中药组，苯那普利为西药对照组，从而观察生化指标、病理改变。

With Death guitarist Schuldiner adopting vocal duties, the band made a major impact on the scene.

随着死亡的吉他手Schuldiner接受主唱的职务，乐队在现实中树立了重要的影响。

But he could still end up breakfasting on Swiss-government issue muesli because all six are accused of nicking around 45 million pounds they should have paid to FIFA.

不过他最后仍有可能沦为瑞士政府&议事餐桌&上的一道早餐，因为这所有六个人都被指控把本应支付给国际足联的大约4500万英镑骗了个精光。