肾小球

The expression of AT1R appears to correlate with the branching of ureteric bud cell and the differentiation and proliferation of glomerular and tubular cells.

AT1R与输尿管芽分支不断延长以及肾小球和肾小管的增殖和分化密切相关。

We had the renal biopsy and clinical serum test including urian protein quantitation per day etc. for 25 children with asymptomatic glomerular hematuria, and observed the relationship between them.

对无症状肾小球性血尿患儿25例进行肾活检病理检查，同时行24h尿蛋白定量等临床指标检测，并比较分析。

ResuIt:1. JDD can significantly improve the digestive system symptoms and physical strength of CRF patients. It can also reduce the urine protein.plasma lipids,BUN and Scr notably.The total effective rate of treatment group is 86.67%,better than that of control group(P.05).2.The experiment revealed JDD can restrain the crescendo-developed mechanism of CRF,which is achieved by decreasing blood ET-1,plasma lipids,urine protein etc.lt also can lighten glomerular sclerosis,inhabit uriniferous tubule-interstitial fibrosis.

结果：1。降氮汤能明显改善消化道症状及体力等一般情况，显著降低尿蛋白，血脂和血Scr、BUN，其总有效率86.67％，显著优于尿毒清对照组(P＜0.05)。2，实验发现降氮汤可通过降低血ET-1、血脂、尿蛋白等途径抑制CRF的渐进性发展机制，减轻肾小球硬化和肾小管-间质纤维化，具有肾保护作用。

The norepinephrine infused may increase the visceral-organs blood flow and has excellent effects to glomerular filtration rate and urine during the vasodilating status not like normal circulation.

在血管舒张状态，并不像正常循环情况，使用去甲肾上腺素可以提高内脏器官血流，并对肾小球滤过率和尿量具有良好效果，同时由于其使用可以避免过度扩容维持血压所引起的脏器功能恢复延迟。

Results No significant changes were found regarding mifepristone doses to the morphologic observation and further the image analysis of hearts,lungs,livers,kidneys,cerebrums of fetal rats and hearts,lungs,livers,kidneys,spleens of pregnant rats among three groups,except enlarging pregnant renal corpuscles areas from image analysis comparing the large dose group to the placebo group.

结果 胎鼠的心、肺、肝、肾、大脑和孕鼠的心、肺、肝、肾、脾的镜检与图像分析结果，除图像分析显示大剂量组肾小球面积较对照组增大外，其余未发现统计学差异。

Pathohistologic examination revealed normal glomeruli but vacuolar degeneration of tubular epithelial cells, and part of them disrupted and desquamated, and also tubular dilatation. Only mild pathological changes were seen in the intervention groups.

肾脏病理检查可见LPS组肾小球大致正常，而肾小管上皮细胞空泡变性，部分上皮细胞崩解、脱落，管腔扩张，两个UT干预组肾小管病理变化均较LPS组减轻，不同剂量组间形态差异无显著性。

Results: in contrast with model group, SSM can (1) increase the survival rate of ARF in rats, cut down Scr and BUN at 24hr, improve renal function, slightly surpass Vp in its therapeutic effect;(2) mitigate the extent of renal pathologicchanges, decrease the numbers of renal tubule necroses and casts;(3) protect renal ultrastructure such as microvilli, mitochondria, endoplasmic reticulum of TEC, podocytic process of glomerulus epithelial cell,endothelial cell etc, better than Vp;(4) enhance SOD activity, lower MDA contents in renal cortex;(5) enhance NO contents in serum, reduce ET levels in plasma;(6) evidently cut down TNF- a contents in serum, superior to Vp;(7) antagonize calcium overload in TEC;(8) alleviate renal pathological changes in ARF metaphase (at 3d), advance regeneration and recovery of TEC, restore renal structure in ARF convalescence (at 5d), and better than Vp;(9) increase the expression of TEC PCNA and prepro EGFmRNA in ARF metaphase.

结果：与模型组相比，SSM能(1)提高ARF大鼠的存活率，降低24hr时Scr及BUN，改善肾功能，其疗效略优于维拉帕米；(2)减轻ARF肾脏病变程度，减少24hr肾小管坏死数及管腔内管型数；(3)对肾脏的超微结构如肾小管上皮细胞微绒毛、线粒体、内质网、肾小球上皮细胞足突、内皮细胞等形态结构均有一定的保护作用，其疗效略优于维拉帕米；(4)提高肾皮质SOD活性，降低MDA含量；(5)提高血清NO水平，同时降低血浆ET含量；(6)显著降低血清TNF-α的水平，疗效明显优于维拉帕米；(7)拮抗小管上皮细胞[Ca~(2+)]_i的升高；(8)使ARF中期(第3d时)肾组织病变较同期其它两组明显减轻，并使肾小管细胞再生修复提前，至ARF恢复期(第5d时)肾组织结构恢复重建良好；作用明显优于维拉帕米；(9)促进ARF中期肾小管上皮细胞PCNA的表达及EGF前体mRNA的合成，从而增加EGF的合成释放，而维拉帕米无此作用。

Objective:To study the effect of Shenkang injection on interleukin 1 secreted by human mesangial cell.

目的 ：探讨中药肾康注射液对肾小球系膜细胞产生IL 1的影响。

Results After 3 months of kidney radiation by 15 Gy of Cs137 γ-rays, the changes with kidney shrank, Bowman's capsules straitened or disappeared, glomerular swelled, some epithelia denaturalized or died were observed. Mitochondria tumefied and the cristae shortened, lessened and disordered. Urine β2-MP rose evidently. It was lowered significantly the renal 25-OH-D-1α-hydroxylase activity and its mRNA expression. The dry and ash weight, BMD of femur and lumbar were significantly reduced, volume and width of bone trabecula were distinctly decreased and the space increased in model group. The Pyd / Cr increased and ALP decreased as well.

结果 15Gy 137Cs-γ射线肾局部照射3个月后肾脏体积缩小，肾小球肿大，Bowman氏囊囊腔狭窄甚至消失，部分肾小管上皮细胞变性、坏死，线粒体肿胀，体积增大，线粒体嵴变短、减少、排列紊乱；尿β2-MP显著增加；肾1α羟化酶活性及1α羟化酶mRNA基因表达量明显下降；肾辐射组股骨干重、灰重、腰椎和股骨BMD明显降低；骨小梁体积和骨小梁宽度减少，骨小梁间距增加，MAR减小；腰椎压缩和股骨三点弯最大载荷明显降低，Pyd / Cr值明显增加，ALP显著降低。

The serum creatinine, blood urea nitrogen and albumin were determined in order to calculate the glomerular filtration rate according to formula.

测定患者血清肌酐、非蛋白氮及血白蛋白，根据MDRD公式计算肾小球滤过率。

It has been put forward that there exists single Ball point and double Ball points on the symmetrical connecting-rod curves of equilateral mechanisms.

从鲍尔点的形成原理出发，分析对称连杆曲线上鲍尔点的产生条件，提出等边机构的对称连杆曲线上有单鲍尔点和双鲍尔点。

The factory affiliated to the Group primarily manufactures multiple-purpose pincers, baking kits, knives, scissors, kitchenware, gardening tools and beauty care kits as well as other hardware tools, the annual production value of which reaches US$ 30 million dollars.

集团所属工厂主要生产多用钳、烤具、刀具、剪刀、厨具、花园工具、美容套等五金产品，年生产总值3000万美元，产品价廉物美、选料上乘、质量保证，深受国内外客户的青睐