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Mitochondria was relatively little in size. Round primary lysosome with high electron-densed granules and secondary lysosome with high or low electron-densed granules were seen frequently. DCs contained many rough endoplasmic reticulum, the Golgi apparatus and ribosomes. The vacuoles with flocculent electron-densed granules were rare. Some special granules in cytoplasm were seen, whose surface like earphone were covered with a membrane. High electron-densed contents in the granules were near one side and the other side was bright. The nucleus became markedly small in volume, nephroid or hoofed in shape. The nucleus had little euchromatin and lots of heterochromatin under nuclear membrane.

子宫内膜癌组织DC超微结构特征如下:细胞形态不规则,与正常子宫内膜组织DC相比,胞膜较光滑,胞膜表面树突状胞浆突起显著减少,部分突起呈粗短状;胞质中线粒体相对少,圆形而电子密度高的初级溶酶体和不规则形且电子密度高低不一的次级溶酶体多见;高尔基体、粗面内质网、核糖体丰富;含微量絮状电子致密物的胞饮小泡显著减少;胞质中可见形态特殊的颗粒,该颗粒外周膜包裹,略呈圆形,中间部位稍弯曲,如耳机状,颗粒中由高电子致密物居于一侧,而另一侧则呈透亮状;胞核显著减小,居于胞质一侧,常呈肾形或马蹄形,核内常染色质较少,异染色质多边集于核膜下。

Methods Surgical specimens/cell suspensions wore transplanted into the various tissues of BALB/c node mice (subcutis, cellular orthotopic injection into renal capsule, perinephrium, surgical orthotopic implantation into renal capsule). Tumorigenicity and metastasis were subsequently cvaluated. Immunohistochemical analysis was employed to determine the expression of VFGF, bFGF, P16, Bcl-2 and C-met in the metastatic and non-metastatic RCC xenograft.

采用皮下移植法、细胞悬液原位注射法、肾周筋膜内法、组织块原位移植肾包膜下法对BALB/c裸小鼠接种RCC组织块,观察各种方法的成瘤及转移情况,并采用免疫组化方法初步对比分析了VEGF、bFGF、P16、Bcl-2、C-met在裸小鼠体内的转移性和非转移RCC的表达情况。

Methods Analyse the CT features of 100 cases with Acute Pancreatitis retrospectively; focus on the involved parts,the eperiphery and the interval behind peritoneum, especially the part of tendon velamen in front of the kidney.

回顾性分析100例急性胰腺炎的CT表现,重点观察胰腺的受累情况,胰周及腹膜后间隙,特别是肾前筋膜的受累情况。

Methods: Between November 2003 and December 2005, 67 patients with renal cell carcinoma underwent retroperitoneal laparoscopic radical nephrectomy (34 patients, group A) and open radical nephrectomy (33 patients, group B). Operating time, blond loss, amount of postoperative drainage, time to ambulation, recovery of intestinal function after operation, the postoperative hospital stay, use of antalgesic and transfusion blood and plasma were compared between group A and group B, retrospectively. Results: In group A, the operations of 31 patients were successful and 3 cases failed, then conversed to open surgery. Firstly, one case were not decented the prerenal fascia and the other two cases occurred complications, one case was due to injurying genital gland vein, with blood loss of 500m1, another fatty renal capsula was too thick to explose the renal pedicle. The operations of group B were all successful, only one case was died of intracerebral hemorrhage after two monthes.

回顾性分析和比较后腹腔镜肾癌根治性切除术(Retroperitoneal laparoscopic radical nephrectomy, RLRN)34例与开放性肾癌根治性切除术(Open radical nephrectomy, ORN)33例,比较两种方法的手术时间、术中出血、术后引流、术后最早下床活动时间、肠功能恢复情况、术后住院时间、术后镇痛剂使用量、术中术后输血、血浆量、术后随访时间及手术效果结果:A组中1例因最初对解剖结构难于辨认,无法分离肾前筋膜至肾门而改行开放手术,1例因损伤精索静脉出血难以控制而改行开放手术,1例因肾周脂肪过多,无法将肾脏掀起显露肾蒂而行开放手术,31例手术成功。B组手术均获成功,1例术后2个月因大面积脑出血死亡,余均无瘤生存。

We evaluated 350 tumors: 136 ES, including 64 conventional ES, 64 proximal-type ES, and 8 with hybrid features of conventional and proximal-type ES; 54 metastatic carcinomas (22 from lung, 6 breast, 6 stomach, 5 colorectum, 5 kidney, 5 prostate, 5 pancreas); 12 metastatic testicular embryonal carcinomas; 20 metastatic melanomas; 20 epithelioid mesotheliomas; 20 epithelioid angiosarcomas; 10 epithelioid hemangioendotheliomas; 24 epithelioid malignant peripheral nerve sheath tumors; 22 myoepithelial carcinomas of soft tissue; 7 anaplastic large cell lymphomas; 5 histiocytic sarcomas; and 10 control MRT of infancy (4 brain, 3 liver, 2 soft tissue, 1 kidney).

我们总共研究了350例肿瘤:136例ES,其中包括64例寻常型ES、64例近端型ES和8例混有前两型特征的混合型ES;54例转移癌(22例来自肺、6例来自乳腺、6例来自胃、5例来自结直肠、5例来着肾、5例来着前列腺、5例来着胰腺);12例转移性睾丸胚胎性癌;20例转移性黑色素瘤;20例上皮样间皮瘤;20例上皮样血管肉瘤;10例上皮样血管内皮瘤;24例上皮样恶性外周神经鞘膜瘤;22例软组织的肌上皮癌;7例间变性大细胞淋巴瘤;5例组织细胞肉瘤;10例作为对照的婴幼儿MRT(4例位于脑、3例位于肝、2例位于软组织、1例位于肾)。

Objective: To describe the anatomy of the superior and inferior aspect of the perirenal space as well as the renal fascia with CT radiography in vivo.

目的:通过对正常成人活体肾周间隙和肾筋膜的多层螺旋CT及三维重建图像的观察和测量分析,探讨肾筋膜的附着、肾周间隙的纵向通连情况等相关指标,以及多层螺旋CT对肾周间隙通连研究的诊断价值。

D. N big mouse model was successfully made by adopting single side kidney cutting with induction, then by 24 week continuos observation on the change of various values of kidney and function, through testing of immunity florescence, electro-scope and optical scope, what we can see from model group is that typical kidney small cell got hardened by knot, and discarded, and dead, also small tube withered, small cell of on base film got thick, cell capsule wall was fibred, and base film got double layered.

实验研究采用单侧肾切除加以链脲佐菌素诱导,成功地复制出糖尿病肾病大鼠模型,对其肾脏结构和功能的改变各项指标,连续进行24周动态观察,并进行免疫荧光、电镜、光镜检测,结果表明:糖尿病肾病模型组可见典型的肾小球节段硬化、废弃、坏死,有大量蛋白管型,肾小球管糖元空泡沉积及脂肪滴,肾小管萎缩,肾小球基底膜明显增厚,球囊壁纤维化,基底膜双层化,有一例结核性肉芽组织及钙化等病理变化。

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