肽酶

Moreover, the size of the molecule and steric hindrance showed obvious effects on the interaction, while the configuration, sequence and length of carbon chains (increasing 1～2 C) of amino acid residue in the phosphoryl oligopeptides showed little effects on the interaction under ESI-MS conditions.

磷酰化二肽中氨基酸残基的构型、顺序、碳链长短的变化(增加1～2个C)对其与蛋白溶菌酶之间的相互作用在质谱中没有表现出影响。

In the first part, twelve peptides, including eight conservative amino acid residues in the amino acid sequence of hydrophilic S helix of AOX. were synthesized by solid-phase method. The polypeptide was coupled to a -chymotrypsinogen, and the antibodies were obtained through immunizing rabbit by injecting this complex.

第一部分，我们按照交替氧化酶(Alternative Oxidase，AOX)位于线粒体内膜外侧亲水区S螺旋的氨基酸序列，用固相法合成由12个氨基酸残基组成的多肽，将此多肽与α-牛胰凝乳蛋白酶原A相连，用作半抗原，免疫家兔制备人工合成12肽的抗体。

The new method can also be used to predict the cleavability of an oligopeptide by HTV-2 protease and it also yielded a very high rate of correct prediction for both the training and testing sets.

这种新方法也可以用来预测HTV-2蛋白水解酶寡肽的断裂，试测和实测中也得到了很高的预测率。

The mean accuracy (Kabsch and Sander, 1983) in predicting the cleavability by HTV-1 protease for the 94 oligopeptides with the 2-4—6 subsite-coupled model developed in this article is 97.9%, while that by the h function method for the same set of data is 85.1%.

在这篇文章中创建的2-4—6亚位点耦合模型预测94个寡肽的HTV-1蛋白水解酶断裂的平均精度(Kabsch and Sander， 1983)是97.9%，而用h功能法得到的预测数据是85.1%。

This invention provides a method for inhibiting the growth of a microorganism that expresses Peptide Deformylase by contacting the microorganism with an effective amount of the compound described herein.

本发明提供了一种抑制表达肽去甲酰酶的微生物生长的方法，它通过使所述微生物与有效量的本文描述的化合物接触。

Further provided is a method for alleviating the symptoms of an infection by a Peptide Deformylase expressing microorganism in a subject by administering or delivering to the subject an effective amount of the compound described above.

进一步提供了一种缓解受试验者中受肽去甲酰酶表达微生物感染的症状的方法，它通过对受试验者施用或送递有效量的上述化合物。

The bioinformatics analysis showed that the gene had the highest homology with the gene of Penicillium janthinellum, which reached up to 76%. The first 26 amino acids might be a signal peptide sequence with the hydrophobicity of up to 2.63. The CBHⅠ gene consisted of the catalytic domain, convergence zone and cellulose-binding domain and its tertiary structure was mainly composed of 3-sheets.

分别扩增到鹅源草酸青霉F67纤维素酶CBHⅠ基因片段A(EU574736)、5'端序列B1(EU603295)、3'端序列B2(EU652768)及全长基因C(EU727171)，并成功构建真核表达载体pPIC9K-CBHⅠ；生物信息学分析表明，该基因蛋白序列与微紫青霉氨基酸序列同源性最高，达76%，前26个氨基酸为信号肽序列，疏水性可达2.63，由催化功能域、衔接区和真菌性纤维素结合域构成，其三级结构主要为β-sheet。

The pharmacodynamics action of aspirin besides synthesizing generation to see effect of hot, demulcent He Kangyan through restraining prostate element, delay to stimulate peptide, histamine to wait, still oxidize through checking the link of plaque enzymatic, reduce prostate element generate and have the effect that restrains plaque to gather.

阿司匹林的药理功能除了通过抑制前列腺素、缓激肽、组胺等合成产生解热、镇痛和抗炎功能外，还通过抑制血小板的环氧化酶，减少前列腺素的生成而具有抑制血小板聚集的功能。

Serum maleic dialdehyde, superoxide dismutase and glutathione peroxidase were determined by spectrophotometer before and after treatment.

治疗前后采用分光光度计法测定两组血清丙二醛、超氧化物歧化酶和谷胱甘肽过氧化物酶。

They are involved in degrading the contents of Maleic Dialdehyde in osteoblast, and elevating activity of Superoxide Dismutase and Glutathion peroxidease.

表现在可以降低成骨细胞中丙二醛含量，提高超氧化物歧化酶和谷胱甘肽过氧化物酶活性。

Breath, muscle contraction of the buttocks; arch body, as far as possible to hold his head, right leg straight towards the ceiling (peg-leg knee in order to avoid muscle tension).

呼气，收缩臀部肌肉；拱起身体，尽量抬起头来，右腿伸直朝向天花板（膝微屈，以避免肌肉紧张）。

The cost of moving grain food products was unchanged from May, but year over year are up 8%.

粮食产品的运输费用与5月份相比没有变化，但却比去年同期高8％。