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In preclinical studies, oral active DPP-IV inhibitors also promoted -cell proliferation, neogenesis, and inhibition of apoptosis in rodents.

临床前研究显示,啮齿类动物经口给予二激酶IV抑制剂(如sitagliptin与 vildagliptin)也引起促进β细胞增生与胰岛新生,抑制β细胞碉亡的作用。

Ultimately, vulnerable groups of neurons atrophy and die in a process that may involve excitotoxicity (overstimulation of neurotransmitter receptors on neuronal surface membranes), collapse of calcium homeostasis, inflammation, and depletion of energy and growth factors. A form of apolipoprotein E, apoE4, contributes to the abnormal accumulation of A and tau, but probably also damages mitochondria and the cellular cytoskeleton. A , tau, apoE and -synuclein interact with many other molecules and modulate diverse signalling cascades that regulate neuronal activity and survival.

最后,易感神经元会萎缩直至死亡,原因可能有兴奋性中毒(神经递质对神经元表面受体的过度刺激引起),钙稳态失衡,炎症反应,能量和生长因子的耗尽。apoE4的产生可导致A和tau蛋白的异常聚合,可能也损害线粒体和细胞骨架。A、tau蛋白、apoE和突触核蛋白可与很多分子反应,也可调节不同信号级联反应,这些级联反应对于维持神经元活动性和生存性意义重大。

Interestingly, the Glu-Cys dipeptide is an exclusive feature of the only obligatory foods in the early life of mammals and oviparous species, i.e., milk and egg white respectively.6

有趣的是,谷氨酰转酶双是哺乳动物和卵生动物在生命早期的必需食物中所独有的成分(6)。

Objective To investigate the distribution and activity of tripeptidyl peptidase Ⅰ in rat tissues under the normal conditions.

目的 探讨大鼠三酶Ⅰ在正常大鼠组织中的分布及活性。

Objective To explore the relationship between dipeptidyl peptidaseⅡ and the pathogenesis of congenital cataract.

目的:探讨二酶Ⅱ与先天性白内障发病的关系。

To explore the relationship between dipeptidyl peptidaseⅡ and the pathogenesis of congenital cataract.

目的:探讨二酶Ⅱ与先天性白内障发病的关系。

The drug is the world's first, is the first in China's listed for the treatment of type 2 diabetes, dipeptidyl peptidase -4 (DPP-4) inhibitors.

该药是世界上第一款,也是首个在中国上市的用於治疗2型糖尿病的二酶-4(DPP-4)抑制剂。

Aim To find novel dipeptidyl peptidase IV inhibitors with thiazole rings and to test their anti-diabetic activities.

摘要目的合成一类新型的以噻唑环为母体的二酶IV抑制剂,并测试它们在治疗糖尿病方面的活性。

AIM: To investigate the immune expression of dipeptidyl peptidase II in the normal eyeball tissues.

目的:探讨二酶II(dipeptidyl peptidase II,DPPII )在正常大鼠眼球各组织中的免疫表达。

Peptidase An enzyme that is responsible for catalyzing the hydrolysis of certain peptide bonds.

酶:指一类促进某些键水解的酶。

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推荐网络例句

Breath, muscle contraction of the buttocks; arch body, as far as possible to hold his head, right leg straight towards the ceiling (peg-leg knee in order to avoid muscle tension).

呼气,收缩臀部肌肉;拱起身体,尽量抬起头来,右腿伸直朝向天花板(膝微屈,以避免肌肉紧张)。

The cost of moving grain food products was unchanged from May, but year over year are up 8%.

粮食产品的运输费用与5月份相比没有变化,但却比去年同期高8%。

However, to get a true quote, you will need to provide detailed personal and financial information.

然而,要让一个真正的引用,你需要提供详细的个人和财务信息。