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After successful setting up the mold, the main organs' tectological changes of big rats can be observed through a light mirror.

动物模型的制作均获得成功,光镜下观察心脏、肺脏、肝脏、肾脏、脑组织细胞形态均有明显的异常改变。

The mice all survived after two weeks. Nanoparticles was harmful to liver and lung to some extent, especially to liver. The modified nanoparticles was little toxical.

经两周观察,未见小鼠死亡情况,纳米颗粒对小鼠的肝脏与肺脏均有不同程度的伤害作用,对肝脏的影响较大,且经过改性的纳米颗粒的伤害作用相对较小。

If intracardiac right-to-left shunt is excluded for the reason of paradoxical gas existence, there remains possible transpulmonary or trans-abnormal vascular fistula passage of the gas.

如果排除心脏右至左分流为造成paradoxical气体栓塞的原因,则剩下可能的机转为经肺脏右至左分流或者肿瘤内存在异常的动静脉廔管。

Materials and methods: The lung preparation of 6 SARS death patient (died in 9,14,20,29,33,38d) and 6 macaque model (killed in 7,12,14,14, 32, 35d)were objects. Pathological changes, collagen fibers, lattice fibers, elastic fibers, collagen I and III in lungs and fine structure changes were studied by routine H.E dyeing, trigeminy dyeing, trinitrophenol- sirius red staining and polarization microscope, electron microscope and image analysis. Expression of Vimentin、 TGFβ_1、 TNF α、 IL-1β and MMP-2 were detected by immunohistochemistry.Results:1. Pathological changes of SARS death patient.

材料与方法:以6例SARS死亡患者(分别于发病后9、14、20、29、33、38d死亡)和6只猕猴实验模型(分别于染毒后7、12、14、14、32、35d活杀取材)肺标本为对象,应用H.E染色、三联染色、苦味酸-天狼猩红-偏振光法、电镜和图像分析等技术,对比性观察SARS肺组织病理变化和纤维化的病理过程、胶原纤维、网状纤维和弹力纤维的变化特点、Ⅰ型与Ⅲ型胶原纤维的数量和分布规律,旨在探讨SARS肺纤维化的病变经历过程及特点;利用免疫组织化学和形态计量学技术检测SARS死亡患者肺脏的Vimentin、TGFβ_1、TNFα、IL-1β和MMP-2等与炎症反应和纤维化相关活性因子,探讨其发病机制。

The findings of the newly identified goose paramyxovirus strain GPMV/HBexperimental infection were as follows: The challenge caused high morbidity and highmortality.The clinical signs included severe depression, decreased appetite or anorexia,white,yellow and green diarrhea, with neural symptoms;pathological changes showed thathaemorrhage and ulceration of intestine mucosa, necrosis of spleen and pancreas,andedema of liver and kidney, uratic deposition in kidney.Eosinophilic inclusion bodies werefound in the cytoplasm of pancreas and a large quantities of fiber protein were found inintestine. Lots of hemosidefin was found in some area of liver and kidney. A number ofT、B lymphocytes reduced sharply in spleen,lymph nodes in dead geese. Transmissionalelectron microscope showed that some cells had the morphological characteristics ofmitochondria swelling, morphological changes were condensation of nuclear chromatininto dense masses,followed by its marginating against the nuclear envelope, andespecially concentration of cytoplasm association with lots of lipid droplet.

人工感染雏鹅实验中,雏鹅临床表现为高发病率和高死亡率,食欲和饮水减少,拉白色、黄绿色稀粪,伴有神经症状;常规组织学观察,脾脏和胰腺肿大,有白色坏死斑点,肠道出血和坏死,肝脏肿大变性,肾脏肿大变性有尿酸盐沉着等;用特殊染色和组织化学方法首次对人工感染鹅副粘病毒的雏鹅的重要脏器进行研究,结果表明:胰腺中发现病毒包涵体,肠道中大量纤维素以及胶原纤维增生,肾脏、肺脏大量含铁血黄素沉着,免疫器官如脾脏和淋巴结中T、B淋巴细胞大量减少;电镜下多种细胞呈现线粒体水肿,多种实质细胞的染色质固缩,染色质边集,特别是细胞内容物如脂肪滴增多的病理变化特征。

The lungs themselves are passive , only inflating and deflating because the walls and floor of the thoracic cavity move .

肺脏他们自己是被动的,仅仅膨胀和紧缩因为胸部的洞行动的墙壁和地板。

Newly developed by the brilliant scientific minds of our age, the Mustard Gas Grenade demoralizes one's opponents by burning the very membranes from their lungs!

{最近由当今时代最杰出科学家们的智慧所开发出的,&芥子神经毒气手雷&能够通过由肺脏开始灼烧他们的各个隔膜来挫败使用者的敌人!

Meconium. The fetal bowel contents consist of various products of secretion, such as glycerophospholipids from the lung, desquamated fetal cells, lanugo, scalp hair, and vernix.

胎粪胎儿肠内容物由许多成分组成,包括肺脏分泌的甘油磷酸脂类物质,脱落胎儿细胞,胎毛,头发和胎脂。

The parietal pleura lines the inner chest wall and the visceral pleura encases the lungs.

壁层胸膜在胸壁内部,脏层胸膜包裹肺脏

Methods and Results— We investigated the expression of PDE1 in explanted lungs from idiopathic PAH patients and animal models of PAH and undertook therapeutic intervention studies in the animal models.

方法与结果—我们研究了来自原发性PAH病人和PAH动物模型分离的肺脏中PDE1的表达情况,并且在动物模型中进行了治疗性干预研究。

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