肺癌

Conclutions Topotecan is an effective remedy for treatment of small cell lung cancer, both single topotecan and combined regimen has the same effect as the traditional first-line regimen, though myelo-suppression such as leucopenia and thrombopenia is more sever, the adverse effect is tolerated. Though it has been recommended as second-line agent for chemo-therapy sensitive small cell lung cancer, there needs more clinical studies to verify its role in first-line.

结论拓扑替康是在小细胞肺癌的治疗中有确切临床疗效的药物，无论是单药还是与其他药物的联合用药均具有与当前一线经典方案相当的疗效，虽具有相对高的致白细胞和血小板下降的骨髓毒性，但毒副作用可耐受，已经被认为是治疗对化疗敏感的小细胞肺癌患者的二线推荐药物，但是作为一线用药仍然需要更多的临床证据来证实。

Objective: To explore the role of p53 gene deletion and CD44V8-10 abnormal expression in the development of lung cancer, and the application valuate in the molecule pathological diagnosis.

目的：探讨p53基因缺失与CD44v8-10异常表达在肺癌发生演进中的作用及其对肺癌分子病理诊断的应用价值。

Objective: To explore the role of p53 gene deletion and CD44V8-10 abnormal expression in the development of lung cancer, and the application valuate in the molecule pathological diagnosis.

中文摘要：目的：探讨p53基因缺失与CD44v8-10异常表达在肺癌发生演进中的作用及其对肺癌分子病理诊断的应用价值。

Results］CEA in 51 patients were positive(69%),9 cases were positive on cellular diagnosis in sputum,56 patients were diagnosed lung cancer by CT, Percutaneous needle biopsy were performed on ,42 patients were treated by operation, and 46 cases(62%) were virtued as lung cancer.

结果］74例患者CEA增高51例（69％），痰脱落细胞学发现癌细胞9例（12％），CT诊断肺癌56例。26例行经皮穿刺肺活检术，42例手术治疗，术后诊断肺癌46例（62％）。

Methods The samples were collected from 55 consecutive patients with tissue diagnosed lung cancers by fiberoptic bronchoscopic brushing. Mutation in coden 12 of H-ras oncogene was detected in the exfoliated cells using PCR-RFLP method (polymerase chain reaction-restriction fragment length polymorphisms).

对33例吸烟肺癌和22例不吸烟肺癌患者采用纤维支气管镜毛刷刷取支气管脱落细胞，应用PCR-RFLP方法进行H-ras基因突变检测。

To detect the value of bcl-2 gene on lung cancer blood metastasis diagnosis and evaluate the effect of Chinese herbs "caning" for lung cancer.

目的 评价bcl-2基因检测诊断肺癌血行转移的应用价值，观察抗癌中药卡宁对肺癌的疗效。

Elucidating the molecular mechanism of tumor invasion and metastasis will provide new molecular targets for gene-targeting treatment of lung cancer.

因此，研究和阐明肺癌侵袭与转移的分子机制必将为肺癌的靶向性基因治疗提供新的靶点和途径。

This paper briefly reviews the research history of the lung cancer due to Radon and its progenies in the past hundreds years,then presents the relationship between risk of lung cancer and radon and its progenies inbreathed by uranium miners.

简要回顾氡致肺癌的长时间认识过程和研究历史，简述了当年铀矿工人和矿工吸入氡及其子体与肺癌发病率的关系，指出环境中氡的危害。

But with CT,"we can detect cancer before it has metastasized and the result is a cure rate of 76% to 78%."

她表示，在美国每年大约有170，000位被诊断为肺癌的病例，而且大约160，000位病患死亡，治愈率低於10%，但是她表示每年以CT筛检，我们可以在肺癌扩散前侦测到这个疾病的发生，而且结果将是治愈率可以达到76%到78%。

Chemotherapy alone is not particularly effective in treating NSCLC, but when NSCLC have metastasized, it can prolong survival in many cases.

单用化疗，是不是特别有效的治疗非小细胞肺癌，但在非小细胞肺癌有转移，它可以延长患者生存，在许多情况下。

According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm～150rpm时取得最大值，此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世，形体几无变化。