肺癌

OBJECTIVE The aims of this study are to observe the effect and acute side-effects of 192-Iridium high dose rate intrabronchial brachytherapy combined with bronchial artery infusion chemotherapy and radiotherapy on non-small cell lung cancer, and also to assess the clinical value of the treatment of HDR-IBB combined with BAI and RT, and to explore a new method of combined treatment for inoperable non-small cell lung cancer MATERIALS AND METHODS Between May 1998 and Octob...

中文摘要：一、目的：本课题观察了~(192)Ir高剂量率支气管腔内放疗对支气管动脉灌注化疗和外照射治疗非小细胞肺癌疗效的影响和副作用，初步研究探讨联合治疗的临床价值，目的在于为不能手术或不愿手术的局部中晚期非小细胞肺癌患者，探索一种新的综合治疗方法。

The objective of this work is to investigate the expressions of CCR7 and VEGF-D protein in non small cell lung cancer and the relationship of their expressions with LVD and lymph node metastasis, and through CCR7 gene transfection to study its impact on VEGF-D expression, and to reveal the molecular mechanism of CCR7-induced lymphangiogenesis and lymphy node metastasis in NSCLC.

本文通过研究CCR7、VEGF-D蛋白在非小细胞肺癌组织中表达及其与淋巴管密度、淋巴结转移之间关系，并通过转染CCR7基因研究其对VEGF-D调控机制，目的揭示CCR7诱导肺癌组织淋巴管形成促进转移的分子机制。

The results were showed that DPC was increased in lung cancer tissues comparing with its neighbored normal tissues , suggesting that DPC may play a part in the development of lung cancer.

结果显示，肺癌组织DPC 的平均水平较癌旁对照肺组织高，提示较高的DPC 水平可能与肺癌的发生或促进有关。

Single-location enhancement is of great importance in differentiating benign and malignant pulmonary nodules, especially in noncalcified pulmonary carcinoma and tuberculoma. It can improve the accuracy of diagnose of pulmonary carcinoma significantly.

同层动态CT增强扫描技术对良、恶性肺结节，尤其是非钙化性肺癌与肺结核瘤的鉴别诊断作用较大，可明显提高肺癌性结节的定性准确率。

Objective To study the clinical characteristics of primary bronchogenic carcinoma with metastases of phalanges of fingers as its first symptom and the mechanism of tumor metastasis to phalanges of fingers.

目的 探讨原发性肺癌以单纯指骨转移为首发症状的临床特点以及肺癌发生指骨转移的机理。

Methods Expression of the survivin mRNA was evaluated by reverse transcriptase polymerase chain reaction in 76 NSCLC tumor samples,20 benign phymatoid lesion and 21 adjacent normal lung tissue samples Immunohistochemical assay was to detect the expression of P53,c myc,k ras proteins.

研究细胞凋亡的调节机制对于弄清肿瘤包括肺癌的发病机制及新的防治方法具有重要意义。survivin是最近发现的一种凋亡抑制蛋白，在已检测的几种肿瘤组织中表达上调[1 3] ，在肺癌中的表达目前报道甚少，其与

In lung cancer tissues, benign phymatoid lesions, and adjacent non cancer lung tissues, telomerase activity was determined by telomeric repeat amplification protocol assay, and the expression of human telomerase RNA component, human telomerase reverse transcriptase, and human telomerase associated protein(hTEP1) mRNA were detected with reverse transcriptase PCR. The results were compared with the histological types, degree of differentiation, and TNM stage of lung cancer.

用 TRAP法检测端粒酶活性，用逆转录 PCR法检测肺癌组织、肺部良性瘤样病变和病灶旁非癌肺组织的 RNA成分（ human telomerase RNA component，hTR）、端粒酶逆转录酶（ human telomerase reverse transcriptase， hTERT）、端粒酶相关蛋白 1（ human telomerase associated protein， hTEP1）各亚基的 mRNA表达，其结果与肺癌的组织类型、分化程度及 TNM分期进行了比较。

PA-42 is an anticancer active compound and isolated from a Chinese medicine herb, physalis angulata. Physalis angulata has been reported to exhibit anti-tumor effect in several human cancers such as leukemia, lung, colon, cervix, hepatoma and melanomas cancers.

PA-42 是从中草药植物苦蘵中所萃取出来的抗癌活性成份；而苦蘵以往有文献报导能对血癌、肺癌、直肠癌、子宫颈癌、肺癌和肝癌细胞产生细胞毒性的作用。

Physalis peruviana L. is a herb widely used in folk medicine.4 β-hydroxywithanolide E compound isolated from the P. peruviana. The study further confirmed that HWE inhibited cell proliferation and induced cell apoptosis in the human A549 cells.

β-hydroxywithanolide E化合物自秘鲁酸浆Physalis peruviana的茎及叶部位分离之纯化物。A549人类肺癌细胞分别以HWE与5-FU处理，进行抗肺癌活性先筛选出强效之抗癌药物，再进行细胞凋亡机制研究。

The coagulopathy of p atients can be diagnosed according to the changes of TEG.It can be used as refer eces in judging the condition of patients,to prognose and instract the treatment for patients with lung caucer.

肺癌患者体内存在病理性高凝状态，临床可根据TEG的变化诊断肺癌患者凝血状态，对判断病情、预后及指导治疗具有参考价值。

According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm～150rpm时取得最大值，此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世，形体几无变化。