肺癌

The sulfamate moiety in the structure of topiramate is chemically related to known CA inhibitors, and in fact, topiramate inhibits CA activity. To further explore the pharmacological action of topiramate, and clarify the possibility of anti-tumor growth and metastasis of CA inhibitors and its relation with AQP1, we studied the effect of topiramate on adhesion of high metastatic prostate carcinoma to laminin, and established the spontaneous metastatic model of Lewis lung carcinoma to studied the influences of topiramate on tumor growth and metastasis and AQP1 expression in lungs and primary tumors of mice.

为了深入研究托吡酯的药理作用，阐明CA抑制剂和水通道蛋白AQP1相互作用影响肿瘤生长和转移的可能性及其机制，我们研究了托吡酯对高转移的前列腺癌细胞粘附于基质成分层粘连蛋白的影响；以Lewis肺癌自发性转移为模型，考察了托吡酯对肿瘤生长和转移的影响；同时观察了托吡酯对荷瘤小鼠肺组织及原发瘤组织AQP1表达的影响；检测了其对血管新生的作用；利用体外AQP1表达模型，研究了CA抑制剂对AQP1功能的影响；此外，用蛋白质组学的关键技术，通过对模型组与托吡酯治疗组血清蛋白质组的比较分析，来寻找与肿瘤转移相关的蛋白质，探索托吡酯的可能作用靶点。

In 15 cases of small cell lung cancer, 7 cases (46.7%) existed supraclavicular lymph node metastasis.

结果：在68例肺癌患者中，有24例(35.3%)被确诊为锁骨上淋巴结细胞学转移。

Comparing palpation and ultrasound examination, the difference of the accuracy in diagnosing supraclavicular lymph node metastasis was calculated.

对68例有组织病理学证据的原发性肺癌患者进行了锁骨上淋巴结触诊和B超检查，并对肿大淋巴结行B超引导下细针穿刺细胞学检查。

Ultrasound examination can increase the detectable rates of supraclavicular lymph node metastasis of lung cancer as comparing with palpation.

对于原发性肺癌的锁骨上淋巴结检查单纯靠触诊有漏诊的可能，B超检查可以增加锁骨上淋巴结转移的检出率。

Methods: PTEN, MTA1, p73 antibody were marked symphonically with immunohistochemical streptavidin peroxidase conjugated methods in 117 cases of lung cancer tissues.

采用免疫组织化学链霉菌卵白素过氧化物酶连接法，使用抗体PTEN、MTA1、p73对117例肺癌组织进行联合标记。

Objective To appraise the value of bronchofibroscope taking place of thoracoscopy in the staging of lung cancer.

目的：评价纤维支气管镜代胸腔镜术在肺癌分期中的应用价值。

ObjectiveTo appraise the value of bronchofibroscope taking place of thoracoscopy in the staging of lung cancer.

目的：评价纤维支气管镜代胸腔镜术在肺癌分期中的应用价值。

Objective To analyze the causes of computed tomographic misdiagnosis of pulmonary carcinoma.

目的 分析肺癌的CT误诊原因。

The patients were received intervenous drop infusion of 153Sm-EDTMP and ibandranate in treatment group (n=48). The patients were received therapy with 153Sm-EDTMP in control group (n=48). The different of effect of odynolysis, locomotor activity, improvement of quality of life, recovery of osteolysis, toxical and adverse reaction between two group was compared.

96例肺癌骨转移患者随机分为2组，153Sm-EDTMP内放疗加伊班膦酸钠静脉滴注48例，单用153Sm-EDTMP核素治疗组48例，比较2组止痛效果、活动能力、生活质量改善、溶骨病灶的修复及毒副作用。

Objective To discuss the method and effect of tracheobronchial sleeve pneumonectomy for lung cancer.

目的 研究肺叶袖状切除、肺动脉成形术治疗支气管肺癌的疗效。

According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm～150rpm时取得最大值，此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世，形体几无变化。