肺状的

The prominent linear markings seen grossly and radiographically in this lung result from lymphangitic spread of metastatic carcinoma, also known as pulmonary lymphangitic carcinomatosis.

大体图和X线图上所见的明显的线状纹理是由肺的淋巴道转移癌引起的。

The superficial microvascular networks were sparser, while the subpleural microvascular networks were denser. The superficial blood vessels and the interlobular blood vessels were mutual transitional, and the anastomosing between the superficial blood vessels with the subpleural vessels. According to the branching sequence of the subpleural arteriole, it could be divided into the arteriole, terminal arteriole, precapillary arteriole and capillary in turn. The subpleural capillary networks were mainly web-like, while small holes were also found on the cast. The honeycomb vascular networks were various in size and form at a low magnification. The outline of alveolus, alveolar sac, alveolar duct and respiratory bronchiole and terminal bronchiole, made of microvascular networks, could be found in the cut surface.

胸膜面浅层的微血管网稀疏，深层的胸膜下微血管网致密；胸膜面浅层的微血管与小叶间隔的微血管之间相互移行，与胸膜下微血管之间形成吻合连接；根据胸膜下微动脉连续分支的顺序，常可将其分为微动脉、终末微动脉、毛细血管前微动脉和毛细血管四级；胸膜下毛细血管网主要以网络状的形式存在，但在铸型上均可见数量不等的"小孔状"结构；低倍镜下肺实质内微血管网呈现大小不等、形态各异的蜂窝状结构，可以见到由微血管网构成了肺泡、肺泡囊、肺泡管和呼吸性细支气管以及终末细支气管等结构的轮廓。

The mice inoculated with Coxiella burnetii intrana- sally developed interstitial pneumonia,while the primary pathological changes of mice inoculated intraperitoneally are granulomas in spleen and liver.2.The pathological changes became more severe followed the dosage increasing.3.Coxiella burnetii can be detected in spleen and liver at day 2 after inoculation.the lesion became more and more serious from day 2 to day 12.The characteristic changes were observed at day 7,and recovered at day 14. 4.The reticuloendothelial system are main target of Coxiella burnetii.The pathogen was detected in cytoplasm of monocyte -macrophages of spleen, liver, lung, and endothelioid cells of blood vessel. 5. Coxiella burnetii can be found in macrophages lysosomes by electron microscopy. Most of them are round or rod, and polymorphic shape can also be observed in different size.

结果：1、通过不同感染途径的实验证实，滴鼻感染的小鼠主要表现为间质性肺炎，而腹腔注射感染小鼠则以脾脏、肝脏肉芽肿为主要病变。2、通过不同剂量的感染实验发现，随着感染Q热立克次体剂量的加大，动物病变愈加严重。3、通过感染后不同时间的动态病理学观察发现，在腹腔注射后第2d的脾和肝脏即可发现病原体，主要脏器的病理变化从第2d到第12d逐渐加重，第7d动物的病变最典型，至感染后14d动物的受损器官已开始出现修复性变化。4、 Q热立克次体主要侵害机体的网状内皮系统，在感染小鼠的肝、脾、肺和外周血管单核巨噬细胞以及血管内皮细胞胞浆中查见病原体。5、透射电镜观察可见Q热立克次体主要位于巨噬细胞吞噬溶酶体内，呈多形性，多见圆形和杆状，大小不一。

Suis was found in all identifiable crypt areas; SS2 also appeard in marginal zone and periarterial lymphoid sheath of spleen, hepatic sinusoid of liver, interstitium of lung; presence of SS2 was at the cortex where histopathological lesions and expression of inflammatory mediators were observed.

实验表明，SS2主要定殖于扁桃体的隐窝附近；在脾的边缘区和动脉周围淋巴鞘附近、淋巴结的生发中心和皮质内、肝血窦、肺间质和肾小体中均可见菌体状荧光颗粒；在脑组织中发生脑膜炎的区域，如皮层等可检出细菌。

Three-dimensional Matrigel constructs contained aleolar forming units comprised of cells displaying AE2 cellular ultrastructure while expressing the SpC gene and gene product. The addition of tissue-specific growth factors induced formation of branching, sacculated epithelial structures reminiscent of the distal lung architecture.

通过对细胞亚微结构的观察和对SpC基因及其表达产物的分析，研究者发现培养体系中肺组织形成单位中具有能向肺泡II型上皮细胞分化的细胞；而通过添加组织特异性的生长因子，他们还发现这一做法会促进培养组织形成具有分支和囊状上皮结构的类似终末肺泡组织的形态结构。

The positive rates of respiratory symptoms and abnormal lung function in tussah silk processing workers were higher than that in the control workers.5 workers showed inflammation in chest X-ray findings and 15 workers often had fever,they all worked in roving and spinning processes.

结果表明：柞蚕丝生产加工工人的呼吸系统症状阳性率和肺功能各项指标的异常率与相应的对照组相比显著增高。X线胸片有炎症片状影者5人，经常发热的工人15人，且均工作于前纺和后纺工序。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。