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Results Ganmaofang had definite bacteriostatic action on standard strain of staphylococcus aureus and escherichia coli, and clinical dissociative strain of staphylococcus aureus, escherichia coli, klebsislla pneumoniae, Staphylococcus epidermidis, Staphylococcus intermedius, Staphylococcus simulans and beta streptococcus in vitro. Its MIC is between 0.075 g/mL and 0.2 g/mL. Ganmaofang could prolong the survival time of mouse infected by staphylococcus aureus and decrease the mortality of ill mouse, meanwhile it could enhance the survival rate of mouse infected by pneumoniae diplococcus.

结果感冒方体外对标准菌株金黄色葡萄球菌、大肠杆菌和临床分离菌株金黄色葡萄球菌、大肠杆菌、肺炎克雷伯菌、表皮葡萄球菌、中葡萄球菌、溶葡萄球菌、乙型链球菌具有一定的抑菌作用,MIC 0.075~0.2 g/mL,体内可延长金黄色葡萄球菌感染小鼠的存活时间和减少感染小鼠的病死率,对肺炎双球菌感染小鼠可提高感染小鼠的存活率。

Many studies have reported that Klebsiella pneumoniae is associated with ankylosing spondylitis but the mechanism of pathogenesis is remained unclear. The endoplasmic reticulum stress would be induced upon exposure of decapsulated KP in HLA-B27 expression B lymphoblast CA46 cells and non-HLA-B27 expression U937 monocytes. Our previous studies demonstrated that decapsulated KP could up-regulate BiP/Grp78 and calreticulin expressions in a dose- and time-dependent manner. We screen more than 60 kinds of traditional herbs and bioactivity agents and we found that berberine,taurine,extracts of Andrographis paniculata Nees.

许多研究指出克雷伯氏肺炎杆菌和僵直性脊椎炎有相当的关系,但是致病机制仍然不是很清楚,因此我们使用去荚膜克雷伯氏肺炎菌来诱发表现HLA-B27的CA46 B淋巴球母细胞、不含HLA-B27的U937单核球细胞可以产生内质网压力,我们先前的实验指出,随著剂量增加,去荚膜克雷伯菌能够过度调控内质网压力指标蛋白质BiP和Calreticulin表现增加。

Demographical character and life style factors were investigated for all subjects , and their ...

对所有选定的研究对象进行人口统计学特征及生活方式相关因素的调查,同时进行血压、身高、体重、腰围和臀围的测量;采集研究对象血标本,进行血脂、血糖、肺炎衣原体IgG抗体、肺炎支原体IgG抗体、幽门螺旋杆菌IgG抗体和柯萨奇病毒IgG抗体等指标的检测。

The detection rates of methicillin-resistant S. aureus and penicillin-nonsusceptible S. pneumoniae were 15.9% and 84.3%, respectively. The prevalence of ESBLs-producing strains in Klebsiella pneumoniae, Escherichia coli, Serratia spp and Enterobacter cloacae were 31.2%, 46.2%, 94.8% and 16.8% respectively. The resistance rates of Hemophilus influenzae and Hemophilus parainfluenzae to ampicilin were 40% and 36% respectively.

耐甲氧西林金黄色葡萄球菌检出率为15.9%;对青霉素不敏感的肺炎链球菌(包括PISP和PRSP)检出率为84.3%;肺炎克雷伯菌、大肠埃希菌、粘质沙雷菌和阴沟肠杆菌产ESBLs的检出率分别为31.2%、46.2%、94.8%和16.8%;流感嗜血杆菌和副流感嗜血杆菌对氨苄西林的耐药率为36%和40%;铜绿假单胞菌和鲍曼复合不动杆菌对亚胺培南的耐药率分别为10.7%和13.2%。

objective to investigate the infection of mycoplasma pneumoniae in children.methods the glutin agglutination rection was used, the diluting power of antibody of mycoplasma pneumoniae was more then 1:80, it was a positive sample.results 1 817 patients were detected, the positive rate was 30.7%,the female rate was higher than male rate, the highest rate were between three to six years old.conclusion mycoplasma pneumoniae is the main pathogen in children with respiratory tract infection, the positive rate was connected with age and nearly contact each other.

目的 了解肺炎支原体在青少年中的感染情况。方法采用明胶凝集的方法,若抗mp-igm滴度≥1:80,为阳性。结果共检测1817例,阳性率为30.7%,女性阳性高于男性,3~6岁的儿童阳性率最高。结论肺炎支原体的感染是青少年呼吸道感染的重要病原菌,阳性率与年龄有关,密切接触可引起局部流行。

Be specific for Streptococcus pneumoniae, were used to identify 49 alpha-hemolytic streptococcal isolates suspected of being pneumococci.

三种PCR检测方法和一个商品化的试剂盒被用于鉴定49株疑似肺炎链球菌的有a溶血的链球菌,这四种方法都基于对16SrRNA基因的杂交,而且都声称对肺炎链球菌有很好的特异性。

The pathological lesion rate caused by local pneumonia for the progeny swinery of the first-born sows was 3/%, and that for the second -born breeding sows was 11%, being 30% of the pathological lesion rate in the first-born sows, so the health level of more than the second-born breeding sows was more stable.

头胎母猪后代的地方性肺炎痛变率为31%,二胎以上母猪后代的地方性肺炎病变率是11%,为头胎母猪后代发病率的1/3,稳定了二胎以上母猪的健康水平。

Plasma specific antibodies IgA, IgG, IgM to Cpn were measured by microimmunofluorescence test. A group of individuals with Cpn specific IgA (titler:32) suggested chronic Cpn infection were compared with a group of control subjects with IgA (titler:32). Blood specimens were drawn for determination of serum lipids and Cpn antibodies. And the serum lipids profile were compared in the two groups.

横断面研究方法;采用微量免疫荧光法检测血浆中肺炎衣原体特异性抗体,以肺炎衣原体IgA升高(滴度≥1:32)的125名健康体检者为研究组,以性别、年龄近似但IgA必抗体效价不升高(滴度:32)的64名同期体检者为对照组,比较2组血清总胆固醇、甘油三酯水平的差异。

Spearmint oil significantly reduced MDA in lung homogenate, and decreased the expression of Nrf2 protein in lung tissues. Conclusion: Spearmint oil has protective effect on lung injury in COPD rats, since it improves pulmonary inflammation, oxidative alteration, and enhances Nrf2 protein expression.

留兰香油对肺炎克雷伯杆菌和脂多糖引起的大鼠COPD模型的肺部炎症、肺气肿、杯状细胞增生和氧化改变有改善作用,并对肺炎克雷伯杆菌和LPS引起的肺组织Nrf2蛋白表达增强有降低作用。

Objective: To investigate the pathogen and antibiotic sensitivity of serious community acquired pneumonia in our hospital and to evaluate the clinical characteristics of SCAP, aiming at providing evidence for using antibiotic.

虽然抗生素不断的研究、开发与使用,社区获得性肺炎仍然是威胁人群健康的重要疾病,特别是由于社会人口老龄化、免疫损害宿主增加、病原体变迁和抗生素耐药率上升,使社区获得性肺炎,尤其是SCAP面临许多新的问题。

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