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Abstract] Objective To observe the treatment methods of pulmonary alveolar proteinosis.

目的 探讨肺泡蛋白沉积症的治疗方法。

The anastomosing occurred between the pleural superficial and the subpleural vascular networks on the capillary level or the precapillary level. The honeycomb vascular networks were also various in size and form at a low magnification. The venule connected with the pulmonary capillary networks directly at a high magnification. The single capillary networks were found in the alveolar septa. The longitudinal crests and dense round imprints of endothelial nuclei and the clear circular constrictions were found on the surface of the larger vessel in the lung parenchyma. The round imprints of endothelial nuclei also occurred on the subpleural venule and capillary.

胸膜面浅层的微血管与胸膜下微血管之间形成毛细血管水平或毛细血管前水平的吻合;低倍镜下肺实质内微血管网也呈现大小不等、形态各异的蜂窝状结构;高倍镜下肺泡毛细血管与微静脉之间联系紧密;在肺泡隔内毛细血管网成单层分布;肺实质内管径较大的微血管表面可以见到纵行的嵴状结构和密集的内皮细胞核的压痕,以及明显的环形缩窄;胸膜下微静脉和毛细血管表面可见圆形内皮细胞核的压痕。

These results suggested that the lung Fib were activated and produced excess HA, resulting in the excessive accumulation of HA within the lung at the stage of alveolitis during the process of pulmonary fibrosis. However, increased HA synthesis of lung Fib and increased HA levels in BALF merely reflect the intensity of alveolitis and the disease activity rather than the degree of pulmonary fibrosis.

以上结果提示:肺Fib在肺纤维化的早期肺泡炎阶段就处于活化状态,产生HA增多,导致肺内HA的过多聚积,肺Fib产生HA增多和BALF中HA水平的增高可反映肺泡炎的强度和疾病的活动性,但并不能反映肺胶原代谢或纤维化的程度。

Different measures of potentill anserine extract has different effects on endothelial cell of capillary vessel of small rats' alveolar wall. Endothelial cell of capillary vessel of alveolar wall has hyperplasia and hypertrophy in different degrees; it leads to permeability of capillary vessel increasing in different extent. With the situation, different concentration of potentill anserine extract promotes vascular endothelial cell factor of small rat's pulmonary tissue secretion.

不同剂量的蕨麻提取物对小鼠肺泡壁毛细血管内皮细胞的影响不同,肺泡壁毛细血管内皮细胞呈不同程度的增生肥大导致毛细血管通透性呈现不同程度的增加,表明可能和不同浓度的蕨麻提取物促进小鼠肺组织某些血管内皮细胞因子(Vascular endothelial cell factor VECF )的分泌功能有关。

The small rat pulmonary tissue surface of ⅲ and ⅳ group can't see any abnormality; the capillary vessel of alveolar wall dilation appears a little hyperemia in different degree under the microscope.conclusion different measures of potentill anserine extract has different effects on endothelial cell of capillary vessel of small rats' alveolar wall. endothelial cell of capillary vessel of alveolar wall has hyperplasia and hypertrophy in different degrees; it leads to permeability of capillary vessel increasing in different extent.

不同剂量的蕨麻提取物对小鼠肺泡壁毛细血管内皮细胞的影响不同,肺泡壁毛细血管内皮细胞呈不同程度的增生肥大导致毛细血管通透性呈现不同程度的增加,表明可能与不同浓度的蕨麻提取物促进小鼠肺组织某些血管内皮细胞因子(vascular endothelial cell factor vecf )的分泌作用有关。

Significance: hypoxic perialveolar arteriole contracts, more blood flows through sufficient ventilation alveolar and carries on effective gas exchange.

意义:氧分压低的肺泡周围微动脉收缩,较多的血液流经通气充足的肺泡进行有效的气体交换。

The main pathological findings include a desquamative interstitial pneumonia-like reaction with intra-alveolar macrophages and numerous large multinucleated histiocytes that ingested inflammatory cells were admixed with macrophages.

GIP主要病理表现有脱屑性间质性肺炎样反应,即在肺泡腔内有巨噬细胞和大量的多核巨细胞聚集,位于肺泡腔内的多核巨细胞内可见被吞噬的炎性细胞,是GIP的特点。

Then, pH-dependent behavior in both microspecies distribution and molecular electrical charge was described in detail.

其中运用药动学理论来定量描述和解析两抗菌药在大鼠体内两部位分布的动态学行为;使用体外培养的肺泡巨噬细胞单层模型,在依据其理化特性参数的基础上,来解释肺泡巨噬细胞对两抗菌药的吸收机理;并且得到以下初步结论

Three-dimensional Matrigel constructs contained aleolar forming units comprised of cells displaying AE2 cellular ultrastructure while expressing the SpC gene and gene product. The addition of tissue-specific growth factors induced formation of branching, sacculated epithelial structures reminiscent of the distal lung architecture.

通过对细胞亚微结构的观察和对SpC基因及其表达产物的分析,研究者发现培养体系中肺组织形成单位中具有能向肺泡II型上皮细胞分化的细胞;而通过添加组织特异性的生长因子,他们还发现这一做法会促进培养组织形成具有分支和囊状上皮结构的类似终末肺泡组织的形态结构。

We observed the variation of TBIL in obstructive jaundice rats and then made the bile duct ligation model. We also investigated the changed regularity of pulmonary capillary membrane permeability in hyperbilirubinemia, utilized the immunohistochemistry method to study the expression of pro-inflammatory cytokines in lung tissue. To search for the reason about the change of pulmonary capillary membrane permeability when the rats in BDL.

本研究应用了胆总管结扎的梗阻性黄疸大鼠模型,研究了高胆红素血症大鼠肺泡毛细血管膜通透性的变化,并利用免疫组化等方法研究了致炎细胞因子在肺组织内表达的改变,以探索肝功能障碍时大鼠肺泡毛细血管膜通透性发生变化的可能原因。

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The reasons of iron ions content overproof in grade Ⅱ desalting water system,such as variation water quality,contamination of regenerant , operation adjustment of pretreatment system and switching operation of bed were discussed.

对二级脱盐水系统中铁离子含量超标的原因,如来水水质发生波动、再生剂受到污染、预处理系统操作调整、床体运行切换等进行了论述。

You were hired to drum up new business, so go and do it.

公司雇你招徕新业务,你就做你的事好了。

Who is in possession of this?

这是谁的?