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Results Pulmonary carcinosarcna and blastoma both were found to be rare malignant tumors, and both epithelial and mesenchymal elements can be seen under the microscopy with different characteristic features.

结果 肺癌肉瘤及肺母细胞瘤均为肺内罕见的恶性肿瘤,镜下均可见上皮及间质两种成分,但又有其不同之处,手术前很难确诊。

Results Pulmonary carcinosarcoma and blastoma both were found to be rare malignant tumors, and both epithelial and mesenchymal elements can be seen under the microscopy with different characteristic features.

结果 肺癌肉瘤及肺母细胞瘤均为肺内罕见的恶性肿瘤,镜下均可见上皮及间质两种成分,但又有其同之处,手术前很难确诊。

ResultsPulmonary carcinosarcoma and blastoma both were found to be rare malignant tumors, and both epithelial and mesenchymal elements can be seen under the microscopy with different characteristic features.

结果肺癌肉瘤及肺母细胞瘤均为肺内罕见的恶性肿瘤,镜下均可见上皮及间质两种成分,但又有其不同之处,手术前很难确诊。

Lung histomorphological changes were observed by light microscope.

实验评估:酶联免疫吸附法检测各组动物血液、肺组织匀浆及肺泡灌洗液中的白细胞介素6、白细胞介素8和肿瘤坏死因子α含量;光镜下观察肺组织形态学变化。

METHODS:Hind limbs ischemia was made by clamping infrarenal aorta with a microvascular clip and lung injury was made by following reperfusion. Lung tissue was obtained from the animals subjected to sham operation, 4 h ischemia without reperfusion and 4 h, 8 h, 16 h, 24 h, 48 h reperfusion following 4 h ischemia. The levels of HO-1 mRNA and protein were measured at different times by Northern blot and Western blot.

采用夹闭大鼠腹主动脉下段造成双下肢缺血和再灌注性肺损伤模型,分别采集假手术组,缺血4 h组及缺血4 h再灌注4、8、16、24、48 h组肺组织标本,以Northern印迹、Western印迹及免疫组化分析,观察HO-1表达的变化。

Methods: Forty mice were divided into four groups randomly:normal group,model group,ligation group and treatment group.The model was made by the method of partly ligating the recta outside the body.The level of endotoxin in blood plasma was measured by dynamic nephelometric method and the content of TNF-a in blood serum was detected by the method of radioimmunity.(2)After the mice were killed,their left lungs were taken out for bronchi-alveoli fluid, then the content of MDA in BALF was tested by TBA method.(3)The vitality of PAM in BALF was countied on the counting set of erythrocyte,and the blue-dyed cellswere counted, then the percentage of PMN was worked out.(4)The pathological features of the mice\'s lung tissue were observed with routine and ultramicro pathological mechanism.

①将40只大鼠随机等分为正常组、模型组、解扎组、治疗组,以体外直肠不全结扎法造模,以动态浊度法检测各组大鼠血浆内毒素水平,放射免疫分析法检测各组血清TNF-α含量;②大鼠处死后,取左肺进行支气管肺泡灌洗,以TBA法测定支气管肺泡灌洗液中丙二醛含量、白蛋白含量及肺表面活性物质水平;③在红细胞计数盘上作BALF中肺泡巨噬细胞活力计数,计数兰染的细胞数,求出死亡百分率;在光镜下计数BALF沉渣200个细胞,计算中性粒细胞所占百分比。

CT-guided percutaneous transthoracic cutting biopsy is a very valuable way,which diagnosed solitary pulmonary nodule earlier.It should be widely spreaded in the diagnosis of the lung nodulus.

CT导引下肺穿刺切割活检术,是早期确诊肺孤立性结节的一种有效方法。

Objective To discuss the value of percutaneous biopsy of pulmonary permeative pathological changes. Methods The pathological change was performed after getting the tissue by the groove needle punctured the lesion under CT guided.

目的 探讨肺内弥漫性病变经皮肺穿刺切割活检的应用价值方法在CT定位导引下使用槽式切割活检针进行病理组织学检查。

Compared with standard images,bony images showed bony thorax more clearly,especially the ribs overlapped by heart and the subphrenic structures,and soft tissue images showed lung lesions more clearly.

DR标准胸片可显示骨性胸廓结构和肺纹理,图像质量优良;骨骼影像显示骨性胸廓方面优于标准影像,特别是心影和膈下结构重叠的肋骨;软组织影像在显示肺内病灶方面优于标准影像。

Linear opacities appeared in pulmonary fibrosis of gradeⅡor gradeⅢand had statistical significance(P<0.05);Bullae and pneumothorax were mainly in pulmonary fibrosis of gradeⅢ,difference of appearance of the sign had statistical significance(P<0.05).The difference of appearance of ground-glass attenuation,consolidation,nodules and subpleural interstitial thickening had no statistical significance in different stages of pulmonary fibrosis. Honeycomb lung and traction bronchiectasis appeared in pulmonary fibrosis of gradeⅢ.

线状影出现于Ⅱ级和Ⅲ级PF,且具有统计学意义(P<0.05);肺大泡及气胸主要出现于Ⅲ级PF,与其余各级PF之间存在差异(P<0.05);磨玻璃影、实变、结节影及胸膜下间质增厚在各级PF出现的差异无统计学意义;蜂窝肺及牵引性支气管扩张都出现于Ⅲ级PF。

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