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Objective:To study if prenatal exposure to sidestream cigarette smoke influences the expres-sion of surfactant protein Aand surfactant protein BmRNAs in the lung of rat pups.

目的研究孕期被动吸烟对新生大鼠表面活性蛋白A、B基因表达的影响,探讨产前被动吸烟对新生大鼠损伤的机制。

Methods 55 cases of pulmonary nodules were collected on the basis of origin dynamics characteristics. First of all, spiral CT targeted scan, then the basis blood stream dynamics characteristic, carries on three-phase enhancement scannings, according to the targeted scan pulmonary nodules morphology characteristic, biggest CT value of Three-phase enhancement scannings, carried out the qualitative analysis to the pathological change.

搜集55例结节性病变患者,在常规扫描基础上,先行螺旋CT靶扫描,然后依据血流动力学特点,进行3期增强扫描,根据靶扫描结节形态学特点、增强后的最大CT净增值,对病变进行定性分析。

Results: The age of onset, the proportion of smoke, the proportion of cough, expectoration, polypnea, cyanosis, rhonchi and moist rale in two lungs were higher in OS patients than OSAS group, the level of body mass index, neck circumference, the proportion of polypnea, nighttime snore, nighttime apnea, daytime hypersomnolence were higher in OS patients than COPD group, the proportion of heart、pulmonary、kidney、 encephalopathy were higher in OS patients than OSAS group and COPD group, FVC, FEV1, FEV1/FVC, MVV, PaO2, SaO2 were lower in OS patients than OSAS group, FRC, PaCO2 were higher in OS patients than OSAS group, AHI was inversely related to the FEV1, FVC, MVV in Group OS, LSaO2 in Group OS was inversely related to the AHI.

结果:OS组的发病年龄、吸烟者比例、咳嗽咳痰、气促、紫绀、罗音比例均高于OSAS组,BMI、NC、夜间打鼾、夜间呼吸暂停、白天嗜睡的比例均高于COPD组;OS组合并心、、肾、脑等疾病的比例均高于OSAS组及COPD组;OS组的FVC、FEV1、FEV1/FVC、MVV、PaO2、SaO2的值均低于OSAS组,FRC、PaCO2均高于OSAS组;OS组AHI与FEV1、FVC、MVV呈负相关,LSaO2与AHI呈负相关,LSaO2与FEV1、FVC、MVV呈正相关;OS组的最长呼吸暂停时间、S1+2、NREM均高于OSAS组,而LSaO2、REM均低于OSAS组,AHI、最长呼吸暂停时间、S1+2均高于COPD组,LSaO2、S3+4均低于COPD组。

Methods: the impacts on lung index ang death reate of mice infected with influenza virus were observed in the mice infected with virus.

利用甲1型流感病毒FM1,株感染小鼠为动物模型,以指数与指数抑制率和死亡率为评价指标,观察羌银解热汤大、中、小剂量组在小鼠体内的抗流感病毒作用。

The pulmonary artery and renal artery 1, 5cm, pulmo nary tissue and renal tissue 1.5cm× 1.5cm were excised.

、肾动脉长1.5cm,、肾组织1.5cm 1.5cm。

Blood loss of extirpation of one bronchial segment was 10~15 ml.A fter the operation,symptoms of bronchiectasis disappeared.Remainder of the pulmo nary tissue keeps inflating.No residual cavity occurs.

结果:手术平均失血量340 ml,每剔除1支段支气管失血量10~1 5 ml,术后症状消失,膨胀良好,无残腔,膈肌活动度恢复。

We successfully identified JSRV mRNA expression and proviruses DNA in sheep lung tissues infected with JSRV and control group has no postive signals,Validating the use of exogenous virus-specific DNA probes in the analysis of oncogenic proviral integration sites and identification of integrated exogenous proviral sequences.

用地高辛随机引物法标记exJSRV特异的env片段,制备探针,原位杂交检测SPA组织中的RNA及前病毒DNA,结果表明SPA患羊组织内有JSRVenv基因mRNA的表达,同时也检测到了前病毒DNA,而相应的阴性对照却无阳性信号,证实外源性病毒特异的DNA探针在致瘤性前病毒的整合位点和整合的外源性前病毒的检测中具有可信度。

After 1hour,4 and 6hours,bronchoalveolar lavage was done,and the function of PAMs,the amount of PAMs and the lung relative weight were determined.Results Lycopene could increase the phagocytic function of PAMs significantly .

以05,10,30mg/的番茄红素连续给雄性Wistar大鼠灌胃30d,用脂多糖制造大鼠急性损伤模型,分别在1,4,6h后支气管泡灌洗,检测泡巨噬细胞吞噬功能、细胞计数以及相对重等指标。

Methods Male rats were gavaged continuously by lycopene with 0 5,1 0,3 0mg/kg for 30 days;Lipopolysaccharide was used to make the model of ALI rats.After 1hour,4 and 6hours,bronchoalveolar lavage was done,and the function of PAMs,the amount of PAMs and the lung relative weight were determined.Results Lycopene could increase the phagocytic function of PAMs significantly .

以0 5,1 0,3 0mg/的番茄红素连续给雄性Wistar大鼠灌胃30d,用脂多糖制造大鼠急性损伤模型,分别在1,4,6h后支气管泡灌洗,检测泡巨噬细胞吞噬功能、细胞计数以及相对重等指标。

Objective: To discuss characteristic of pulmonary sequestration with comparison of adult and paediatric groups.

目的:通过成人和儿科两组隔离症病例的比较,探讨隔离症这种先天性畸形的疾病特征。

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