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Pulmonary function tests showed restrictive ventilation disturbance and/or a decreased diffusing capacity in 12 patients and normal condition in 4 patients. Chest X-ray films showed multiple patchy consolidation in 12 patients and thickening of lung markings in 4 patients. HRCT scans demonstrated patchy consolidation and/or ground-glass opacity in 16 patients and fine nodular consolidation in 4 patients. The lesions were diffuse in 1 patients and had a predominantiy subpleural and/or peribron chovascular distrbution in 15 patients.

结果:14例患者主要表现为干咳和气短,2例主要表现为发热伴咳嗽。12例患者功能检查表现为限制性通气功能障碍和弥散功能减低,4例功能正常。12例患者X线胸片呈多发斑片实变影,4例表现为纹理增粗。16例患者HRCT扫描表现为多发斑片实变影和磨玻璃影,4例伴小结节。1例病变弥漫分布于双,15例病变位于胸膜下和沿支气管血管鼠分布。

Results On conventional CT, pulmonary window revealed widespread intraalveolar calcifications of both lungs concentrating in the subpleural parenchyma of the middle and lower lobes.

结果常规CT表现:窗示实质内有无数细小散在的粟粒结节,以中下的外周部密集,其CT值为200~400HU,多合并不同程度的气肿及间质纤维化;纵隔窗示细结节影最密集区常呈沿胸膜的线带状或散在的点簇状钙化,形成&火焰征&及&白描征&。

Way flap device at subsegment. Lung functional residual capacity was analyzed before and 8 weeks after operation.

在术前和术后8周测量功能残气量;术后8周处死动物取出完整组织,在萎陷区、非萎陷区和对侧正常组织分别取材,观察大体及光镜下病理学改变。

There is certain clinical value of via right tracheobronchial sleeve pne umonectomy for treating right lung cancer.

对心功能大致正常及无外转移的病例,气管右全袖状切除癌有一定的价值。

Objective: To assess the value of transthoracic echocardiography in the diagnosis and treatment of acute pulmonary embolism.

目的:探讨经胸超声心动图在急性栓塞诊断与治疗中的价值。方法:对经临床综合诊断(包括核素灌注扫描或CT血管造影)确诊为急性栓塞的患者46例进行经胸超声心动图检查。

Materials and methods: The lung preparation of 6 SARS death patient (died in 9,14,20,29,33,38d) and 6 macaque model (killed in 7,12,14,14, 32, 35d)were objects. Pathological changes, collagen fibers, lattice fibers, elastic fibers, collagen I and III in lungs and fine structure changes were studied by routine H.E dyeing, trigeminy dyeing, trinitrophenol- sirius red staining and polarization microscope, electron microscope and image analysis. Expression of Vimentin、 TGFβ_1、 TNF α、 IL-1β and MMP-2 were detected by immunohistochemistry.Results:1. Pathological changes of SARS death patient.

材料与方法:以6例SARS死亡患者(分别于发病后9、14、20、29、33、38d死亡)和6只猕猴实验模型(分别于染毒后7、12、14、14、32、35d活杀取材)标本为对象,应用H.E染色、三联染色、苦味酸-天狼猩红-偏振光法、电镜和图像分析等技术,对比性观察SARS组织病理变化和纤维化的病理过程、胶原纤维、网状纤维和弹力纤维的变化特点、Ⅰ型与Ⅲ型胶原纤维的数量和分布规律,旨在探讨SARS纤维化的病变经历过程及特点;利用免疫组织化学和形态计量学技术检测SARS死亡患者脏的Vimentin、TGFβ_1、TNFα、IL-1β和MMP-2等与炎症反应和纤维化相关活性因子,探讨其发病机制。

In the 1980s,Mason and his colleagues was the first to apply whole lung lavage (either one lung per session or two sequential whole-lung lavages under one anesthesia session)in the treatment of a mixed-dust pneumoconiosis,which is in the operating room undergeneral anesthesia using a doubl...

上世纪八十年代Mason首先用大容量全灌洗术(whole lung lavage,WLL)治疗尘以来,国内1986年开始应用这项技术治疗尘进行实验和临床研究。

Compare the lung injury extent and the important physiological parameters to determine the optimal condition for rabbit ventilator induced lung injury, Choosing another 24 new Zealand rabbit, randomly divided into 4 groups:(1)conventional ventilation+PEEP group;(2)ventilator induced lung injury group: employ the experimental condition determined by the first part experiment;(3)VILI+HO-1 inducer hemin group:pre-treated with HO-1 inducer, the ventilation method is the same with VILI group;(4)VILI+HO-1 inhibitor Zn-PP group(Zn-PP group):pre-treated with HO-1 inhibitor, the ventilation condition is the same with VILI group.

第二部分24只家兔随机分为4组:(1)常规潮气量+PEEP组;(2)呼吸机所致损伤组:使用实验第一部分确定的最适条件;(3)呼吸机所致损伤+HO-1诱导剂干预组:预先给予氯铁血红素,通气条件同VILI组;(4)呼吸机所致损伤+HO-1阻断剂干预组:预先给予锌原卟啉,通气条件同VILI组。

The biochemical composition and the surface activities of pulmonary surfactant were determined in tracheal aspirates from 15 neonates, and bronchcalveolar lavage fluid from 13 rabbits with pulmonary hemorrhage.

作者等测定15例新生儿出血气道吸出物和13只兔出血模型支气管泡灌洗液中表面活性物质的生化成分和表面活性。

Group IR(n=10): Dissociating hilum of left lung and blockading it for forty-five minutes,and then opening hilum of left lung .Two hours and five later, samples were got.

IR组,对照组(n=10),开胸后首先进行左门结构的常规游离,接着阻断门45分钟,开放后不做其他处理,2小时5分钟后留取组织。

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