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The morphologic changes of these three tissues were observed with light microscope and transmission electronic microscope; the pulmonary wet-to-dry weight ratio, the pulmonary weight indexs, and the ratio of the area of the multilamellar body to the area of cytoplasm in type II alveolar cell were measured. Results 1.The permeability of the pulmonary endothelial cells increased 2 hours after the injection of oleic acid.

经光镜和透射电镜观察对照组和实验组三种组织的形态学改变;并测定组织的湿干重比和系数;采用立体计量法测定II型细胞板层小体与细胞质面密度比。

Objective CT-guided percutaneous transthoracic fine needle cutting biopsy was performed in small solitary pulmonary nodulus,to find out the useful way for diagnosis of the pulmonary lesion earlier.

目的 对孤立性结节行CT定位导引下穿刺切割活检术,探讨早期确诊孤立性结节的有效方法。

Reduction in blood flow to the nondependent lung can be caused by an enhancement of hypoxic pulmonary vasoconstriction , which is the main mechanism of decreasing transpulmonary shunt during OLV.

缺氧性血管收缩是减少OLV期间内分流的主要机制,增强HPV可减少OLV期间内分流。

Three hours OLV does not cause injury of the nondependent lung, yet six hours OLV leads to injury of the nondependent lung. Low-dose ALM would not deteriorate the injury of the nondependent lung.

OLV 3hr不会造成无通气组织的损伤,而OLV 6hr则引起无通气组织的损伤:小剂量ALM在提高HPV反应,改善OLV期间动脉氧合的同时,并不加重无通气组织的损伤。

Objective To assess the role of different methods-routine and impulse oscillometry pulmonary functional tests in normal subjects and patients with interstitial lung diseases.

目的探讨常规功能与脉冲振荡功能检测在间质性疾病病人中的应用价值。

Pulmonary function ; impulse oscillometry ; pulmonary fibrosis ; chronic pulmonary disease

功能;脉冲振荡;间质纤维化;慢性阻塞性疾病

Result: A 77-year-old female presented at our hospital for blurred vision in her right eye. The intraocular pressure was 46 mmHg and slit lamp examination showed a protruding mass with papillomatous appearance near pupil margin. On chest X-ray examination, only prominent left hilum was noted. Iris tumor excisional biopsy was performed. Pathology investigation of the surgical specimen revealed carcinoma and immunohistochemical study demonstrated thyroid transcription factor-1 (TTF-1) positive. Chest-computed tomography showed left upper lung tumor and primary pulmonary adenocarcinoma was confirmed after CT-guided biopsy. She was placed under treatment with Genfitinib. Recurrent iris tumor mass was noted during follow-up, and chest CT revealed shrinkage of adenocarcinoma.

结果:一位七十七岁女性因右眼视力模糊至本院就诊,当时眼压为46毫米汞柱,细隙灯检查发现虹膜靠近瞳孔边缘有一乳突状肿块,胸部X光摄影仅见左门稍明显并未发现明显病灶,患者接受虹膜肿瘤切除手术,病理报告显示为恶性肿瘤,且免疫组织染色为thyroid transcription factor-l阳性,进一步的胸部电脑断层显示左上肿瘤,经电脑断层指引之切片检查证实为原发性腺癌,她接受Genfitinib药物治疗,后续追踪发现虹膜肿瘤复发,胸部电脑断层扫描显示肿瘤体积缩小。

At present, the diagnosis pulmonary embolism method has very much, like the pulmonary artery radiography, spiral CT, the magnetic resonance imagery, as well as to doubts examines carries on the strict medical history collection and the electrocardiogram, X sternum inspection for the deep phlebothrombosis pulmonary embolism patient, the clinical symptom, the body draft and correlation diagnosis pulmonary embolism the and so on change method.

目前,诊断栓塞的手段有很多,如动脉造影、螺旋CT、磁共振成像,以及对疑诊为深静脉血栓形成栓塞的病人进行严密的病史收集和心电图、X线胸片检查,临床症状、体征及相关的变化等诊断栓塞的方法。

The loss of normal lung parenchyma leads to pulmonary hypertension that leads to thickening of the small arteries along with reduplication to form a plexiform lesion, as seen here in a peripheral pulmonary artery.

正常实质的损伤可导致血管的压力增高,在此切片动脉的周边部可见内小动脉的管壁增厚,管腔狭窄引起动脉血压增高。

Finally, we established rat model of PF induced by bleomycetin, and observed the interventional action of phenol total base to model. The analysis of experimental result including pathematologic and tissue biochemical indicator showed phenol total base of plumula nelumbinis have some therapeutic action to rat model of PF induced by BLM.

通过病理学观测及组织生化指标的检测(SOD、MAD、GSH一PX、Hyp),说明莲子心酚性总碱对博莱霉素致大鼠纤维化有一定治疗作用,可能的作用机制:降低纤维时胶原含量;抑制成纤维细胞的增殖;抗自由基和抗脂质过氧化作用及提高了机体内GSH一Px含量。

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