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肥大细胞

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The UCN synthesized by interbrain hasimmunosuppressive action. However the UCN synthesized by peripherytissue has proinflammatory function.

另外,肥大细胞可以合成分泌UCN,并且UCN可以诱导肥大细胞脱颗粒产生大量促炎因子。

Objective To study the role of mast cells and mast cell protease 1(RMCP 1)in the myocardial fibrosis after myocardial infarction in rats.

目的观察肥大细胞及大鼠肥大细胞蛋白酶1(RMCP1)在大鼠心肌梗死后心肌纤维化中的作用。

METHODS:Guinea-pigs were sensitized by ovalbumin and the effects of LMWH on the constriction of ileum smooth muscle induced by OA were observed in vitro;The effects of LMWH on the degranulation of pericranium mast cell induced by OA were observed throu gh the passive anaphylaxis ratmodel which was made by vaccinating antiserum at pericranium;Licking response was induced by 4-aminopyridine(4-AP) scat scruff in mice,then the effect of LMWH on licking response was studied the capillary p emeabilty increasing induced by glactal acetic acid and the effect of LMWH on ca pillary pemeability were studied.

用卵白蛋白(ovalbumin,OA)免疫豚鼠造成过敏模型,观察LMWH对OA所致的豚鼠离体回肠平滑肌收缩的影响;在大鼠颅骨骨膜接种抗血清使肥大细胞被动致敏,观察LMWH对OA引起肥大细胞脱颗粒的影响;以4-氨基吡啶诱发小鼠舔体反应,观察LMWH对舔体反应的影响;以冰醋酸使小鼠毛细血管通透性增加,观察LMWH对通透性的影响。

The effect of Alcian blue Safranin O staining was the best, which was applicable to identification of the mast cell of A. Japonica. The improved toluidine blue staining was not applicable.

AB/SO染色法效果最好,适用于日本鳗鲡肥大细胞的鉴定;改良甲苯胺蓝染色法不适合于日本鳗鲡肥大细胞的鉴定。

More recently, the level of adenosine has been shown to be increased its attack in asthmatics, and which played an important role in bronchoconstriction of asthmatic patients.

进一步研究发现腺苷可通过作用于肥大细胞膜上的A2B腺苷受体(A2BAR),促进肥大细胞释放白介素8(Interleukin-8, IL-8)等细胞因子,引发气道的炎症过程。

All of mast cells in larva,adult bufonidae and adult bullfrog were proved to be the mucosal mast cell,which contributed to be first defense in skin mucosal immunity.

蟾蜍幼体、成体和牛蛙成体皮肤肥大细胞均为黏膜肥大细胞,是参与构成皮肤黏膜免疫的第一道屏障。

Concludes: Tryptase and/or chymase contents and subtypes of mast cell are related to intracellular F-actin ring in the tissue of human skin.

人皮肤组织中肥大细胞内类胰蛋白酶和/或类糜蛋白酶的含量及其肥大细胞亚型与丝状肌动蛋白环相关联。

Hepatic chymase concentrations in S3 and S4 cases were greater than in S1 and S2,〔53+54=(31.3±24.6)ng/mg vs. S1+S2=(5.7±4.8) ng/mg, P.01〕. Cells immunoreactive for chymase were seen throughout portal areas and intralobular sinusoidal walls, largely colocalizing with fibrosis. Chymase appears to be involved in hepatic fibrosis in chronic hepatitis.

慢性肝炎纤维化分期重的S3和S4患者,其肝组织中Chymase浓度〔S3+S4=(31.3±24.6)ng/mg〕明显高于纤维化轻的S1和S2患者〔S1+S2=(5.7±4.8)ng/mg〕,P.01;免疫组化染色结果,Chymase标记的肥大细胞主要分布于纤维化旺盛的汇管区与类洞壁,其分布与纤维化部位相一致,且肝组织中Chymase浓度高的患者,其肝组织内Chymase标记的肥大细胞分布增多推测肝组织中Chymase浓度可能与慢性肝炎肝纤维化关系密切。

The MC number of the tubal muscular layer and mucosa is not dependent on the menstrual cycle. Under the effect of mifepristone, the MC number in the wall of the Fallopian tube, except fimbrial mucosa, is less than that of control group.

人输卵管肌层及粘膜的肥大细胞数不受月经周期的影响;在米非司酮作用下,输卵管壁的肥大细胞数均明显低于对照组。

Results The results showed that the number of mast cells around the periphery of gingival cancer tissue increased significantly.

结果 在牙龈癌周围组织中肥大细胞显著增多,在组织化学上与正常牙龈组织的肥大细胞不同,不含肝素。

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