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To explore the change and its significance of the expression of vascular endothelial growth factor messenger RNA and bone morphogenic protein-2(BMP-2) of the local femoral head in the nontraumatic osteonecrosis of femoral head.

探讨非创伤性股骨头发生坏死后局部的血管内皮生长因子(vascular endothelial growth factor VEGF)mRNA与骨形态发生蛋白-2(bone morphogenic proteins,BMP-2)表达的变化及其意义。

Immunohistochemistrical section: observe the VEGF protein expression in different cells, the positive ratio detected by a morphometrical analysis system was used as the amount of the VEGF protein expression.

免疫组化染色切片:观察不同给药时间股骨头内VEGF的表达情况;高倍视野下(400倍)沿骨小梁表面计数50个成骨细胞中的阳性细胞数,VEGF成骨细胞阳性率=阳性成骨细胞数/50×100%,3次取平均值;计数每个高倍视野软骨细胞中的阳性细胞数,VEGF软骨细胞阳性率=阳性软骨细胞数/软骨细胞总数×100%,5次取平均值。

The percentage of necrotic surface does not vary with the development of course of disease.

股骨头坏死的坏死面积比例不随病程的延长及临床分期的进展而改变。

The necrotic surface of femoral head did not vary with the disease development.

股骨头坏死的坏死面积比例不随病程的延长及临床分期的进展而改变。

Treatment of avascular necrosis of femoral head incude operative and nonoperative way.

目前治疗股骨头坏死的方法有多种,主要分为非手术治疗和手术治疗。

It has important sense for the research of this disease to establish animal models with osteonecrosis of the femoral head.

股骨头坏死动物模型的建立对该病的研究有重要意义。

Methods:The clinical data of 17 patients (21 hips)with femoral head osteonecrosis were reviewed.

回顾性分析17例(21髋)股骨头缺血性坏死患者的临床资料。

Objective To explore non-traumatic osteonecrosis of the femoral head of the clinical features and study the development trend of their cause.

目的 探讨非创伤性股骨头坏死的发病特点,研究其病因的发展趋势。

Constructing a finite element model of osteonecrosis of the femoral head.

建立股骨头坏死有限元模型的方法。

But the pathophysiology of osteonecrosis of the femoral head has not been completely elucidated.

目前认为激素和酒精的摄入是股骨头缺血坏死最常见的两大病因。

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每逢看到沃林顿那刚毅的脸,那乌黑、忧郁的眼睛,她便会相信,他一定作过不幸的爱情的受害者。

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