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Compared with normal control group, the proportion of CD4+CD25+ Tregs was markedly decreased in PB and MLN of model control group of experimental colitis. But it was significantly increased in therapeutic groups of SASP and CLYSTER No.

结果:建模后1~2周,模型组外周血和肠系膜淋巴结的CD4+CD25+ Tregs细胞数量较正常组明显下降,而使用SASP和中药灌肠Ⅰ号治疗后该细胞亚群明显高于模型组。

Objective:to investigate the effect of damage control surgeryin the theatment ofacute mesenteric ischemia.methods: a retrospective analysis was made on clinical data of eight cases with ami treated by dcs from june 2006 to december 2007.results: operations were immediately performed in all eight patients with ami after final diagnosis,including six cases treated with different limitation of enterotomy; five with temporary abdominal closure and exteriorization of intestine,three with abdominal closure of venous nutrition transfusion container; seven with two-stage operation in different means.five cases survived or improved three died, one of which died two months after discharge due to short bowel syndrome.conclusion:it is very difficult to treat the ami patients owing to the restriction of technology and equipment.

目的:探讨损伤控制外科在治疗急性肠系膜缺血疾病中的应用。方法:对2006年6月~2007年12月应用dcs理念指导救治的8例急性肠系膜缺血疾病的临床资料进行回顾性分析。结果:对8例急性肠系膜血管缺血疾病均于确诊后立即手术探查,其中6例做了不同范围的肠切除;5例做暂时关腹术加肠外置,3例用静脉营养输液袋关腹;7例进行不同方式的二期手术。本组5例痊愈或好转出院;3例死亡,其中1例为短肠综合征出院2个月后死亡。结论:在治疗急性肠系膜血管缺血疾病病人的治疗中,在许多医院因设备和技术等条件的限制,处理十分困难。

All animal was undertaken resuscitation for 5 hours.Then we observed histopathology change of lung、hepar and kidney,detected blood gas analysis and functional parameter of hepar and kidney,and detected intestine and mesentery vascular permeability.

各组实验动物行液体复苏5小时后,观察肺、肝、肾组织病理学改变,检测血气分析及肝、肾相关功能指标,采取分光光度计测出小肠和肠系膜组织的血管渗透性等。

H and 6 h after hemorrhagic shock and resuscitation a 4-cm midline laparotomy was made and the mesentery near to the ileum was exteriorized and the microcirculation blood flow as well as PMN-endothelial cell interaction was evaluated by means of intravital microscopy.

复苏后2 h和6 h在腹部正中作4 cm切口,取出回盲部附近的肠系膜,显微镜下观察多形核白细胞在肠系膜毛细血管后小静脉内的附壁情况并录像。

Two hours and 6 hours after hemorrhagic shock and resuscitation a 4-cm midline laparotomy was made and the mesentery near to the ileum was exteriorized and PMN-endothelial cell sticking to the venular endothelium was evaluated by means of intravital microscopy and recorded.

复苏后2 h和6 h在腹部正中作4 cm切口,取出回盲部附近的肠系膜,显微镜下观察多形核白细胞在肠系膜毛细血管后小静脉内的附壁情况并录像。

First, we made a model of exhaustive exercise in rats, and used sucessfully the model in this study. We studied the effects of exhaustive exercise on adhesive behaviour of leukocytes in mesenteric venules by using an intravital microscope video system Its results indicated that the adhesiveness of circulating leukocytes to mesenteric venules enhanced after exhaustive exercise in rats.

首先,本文以游泳方法建立了大鼠模拟运动力竭模型,并成功地将此模型运用到本研究中;设计制作了肠系膜固定有机玻璃板,组成了一套活体显微观察实验系统;研究了大鼠运动力竭前后肠系膜微循环中白细胞粘附行为,结果表明:大鼠运动力竭后肠系膜微循环血流流态发生了明显的改变,大鼠运动力竭后肠系膜微循环中白细胞粘附性增强、白细胞滚动速率降低、在体白细胞变形性减小,将影响微循环正常的灌注,是导致微循环障碍发生发展的一个重要原因,进而最终表现为机体运动能力和运动质量下降。

Methods The blood flow parameters of superior mesentric artery and coelia artery in 22 asphyxiated neonates and 30 healthy full-term infants were measured on the first day, the third day and the seventh day of life by using colour Doppler sonography.

应用多普勒超声血流显像技术,对22例(30例次)窒息后新生儿于生后1、3、7天进行了肠系膜上动脉和腹腔动脉的血流各参数测定,并以30例正常足月新生儿作为对照。

There were prerenal fascia posterolateral to the left mesocolon, preaortic fascia median to the left mesocolon, parietal layer of the pelvic fascia posterolateral to the mesorectum, which continued at different sites.

左半结肠系膜后外侧存在肾前筋膜;中线侧存在主动脉前筋膜;直肠系膜后外侧存在盆筋膜壁层。这三个部位的筋膜相互延续。

Dissections both posterior and anterior to the mesosigmoid are effective methods to identify and divide the IMV at high level.

结肠系膜后位和前位解剖法相结合,是识别和定位IMV的有效手段。

Results AE from CM had vasodilating effect on the contracti on of mesentery blood capillary in guinea pigs and the contraction of rat thoracic aortic ring induced by l0μmol/L phenylephrine, even under the condition of pre-treating with glibenclamide (1μmol/L) or propranolol (3μmol/L). When the endothelium of the rat thoracic aortic ring was removed, AE from CM had not vasodilating effect hut constrictive effect. AE from CM could also increase the contents of NO, NOS and cNOS in the aortic tissue and had no obvious effect on the NO content in plasma and iNOS in aortic tissue of rats.

结果 桑白皮丙酮提取物有抑制去甲肾上腺素收缩豚鼠肠系膜微血管的作用,抑制苯肾上腺素(10μmol/L)收缩离体大鼠胸主动脉环的作用,预加优降糖或普蔡洛尔(3μmol/L)后仍然有松弛作用;大鼠胸主动脉环去内皮后药物无松弛作用,反而起收缩作用;显著升高血管的NO和NOS、cNOS含量,对大鼠血浆的NO和血管iNOS的含量影响不大。

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