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In this study, the severe acute pancreatitis specific EN formula was composed based on the rationale of the nutritional mechanism of the disease, and the alanyl- glutminedipeptide was added into the formula. This study was cut in the combining site of clinical nutrition pharmacology and immunology to probe the effect of Gln in the special formula in SAP rat form several aspects including mucous barrier, immunological barrier and systemic inflammatory responses.

本课题研究在成功建立急性重症胰腺炎模型的基础上,在SAP专用肠内营养配方中加入水溶性和稳定性好的丙-谷氨酰二肽,并从临床营养药理学和免疫学的结合点切入,采用免疫学、分子生物学研究手段,重点从肠屏障功能、免疫功能、细胞因子方面研究早期肠内营养加谷氨酰胺防治SAP营养治疗作用机制。

After the germ-free operation of gastrostomy, rats in each group of enteral nutrition were treated with thesocaloric and isonitrogenous nutritional formulas respectively for 7 days.

目的:研究肠内免疫营养对创伤后大鼠肠道屏障功能的影响。方法:将30只Wistar大鼠随机分为3组,即对照组、普通肠内营养组、肠内免疫营养组。

EN is mechanical to alvine mucous membrane the protective screen of machinery of mucous membrane of protective action bowel of protective screen is main by mucous membrane of the mucus layer of surface of alvine mucous membrane, bowel epithelial reach its the composition such as close connection.

肠内营养对肠屏障功能的维护机理是多方面的,EN制剂的种类对小肠功能的改善功能也不相同。1 EN对肠黏膜机械屏障的保护功能肠黏膜机械屏障主要由肠黏膜表面的黏液层、肠黏膜上皮细胞及其紧密连接等组成。

The method comprises: utilizing arctiin as the precursor compound, and converting arctiin into 4, 4'-dihydroxy enterolactone by intestinal bacteria in an anaerobic condition. 4, 4'-dihydroxy enterolactone is lignin compound, and can be converted into phytoestrogen in human intestinal canals.

本发明是以牛蒡苷为先导化合物,在厌氧条件下,以肠道细菌将牛蒡苷转化为4,4′-二羟基肠内酯。4,4′-二羟基肠内酯为木脂素类化合物,在人的肠道中能被转化为植物雌激素―肠内酯而发挥药理作用。

No matter whether the patients of pancreatic diseases have enteroparalysis or not,the enteral nutrition should be administrated at onset or within 24-48 hours postoperatively.

也有学者认为:避开胃和十二指肠的肠内营养无显著加重胰腺损害的危险,胰腺疾病患者无论是否存在肠麻痹,发病或手术24-48小时即可给予肠内营养支持。

Mucous membrane protective screen is formed by the join between cell of alvine mucous membrane and cell, atrophy of cell of alvine mucous membrane, wither dies, cellular connective can send alvine path to connect flabbily appear a gender to increase, provide passageway; chemical protective screen for the bacterium inside bowel and toxin the digestive juice that shows epithelial excretive mucus and alvine memory are in bowel and digest enzymatic the chemistry that waits for material to reach its to develop.

黏膜屏障由肠黏膜细胞和细胞间的连接构成,肠黏膜细胞萎缩、凋亡、细胞连接的松弛可致肠道通透性增加,为肠内细菌及毒素提供通道;化学屏障指肠上皮细胞分泌的黏液及肠内存在的消化液和消化酶等物质及其发挥的化学功能。

Objective To analyse the enteral nutrition effect of needle catheter jejunostomy for patients un-derwent esophagoectomy.Methods 52patients received needle catheter jejunostomy before diaphnagm sutured,the catheter was inserted jejunum at the point20cm distal to the ligament of Treitz.Before getting into the lumen,the catheter merges in the wall of the bowel for a distance about4~5cm.

目的 探讨空肠穿刺置管在食管癌根治术后的肠内营养疗效方法 52例食管癌根治术患者在膈肌关闭,距Treiz韧带20cm穿刺空肠置入Sicone2mm导管,导管在肠壁内潜行4~5cm进入肠腔,再固定予腹壁上,术后1天开始肠内营养。

Results One case with transverse mesocolon pore hernia, one with obturator hernia and one with paracecal hernia were confirmed by exploratory laparotomy. There were six cases whose hernias resulted from the fall of export jejuna into import jejuna after Billroth II anastomoses in front of colons, five from the pelvic bottoms' peritoneal fissure and four from the fissure appearing between descending colon and lateral abdominal wall after Miles' operation, one from greater omental adhesion to sigmoidal wall after sigmoidostomy, and one from inflammatory adhesion on the basis of Meckel's diverticulum. The other 17 cases' hernias (48.7%) were caused by the fissure among celiac adhesive bands, peritonea, celiac organs, enteric walls and intestines.

结果 剖腹探查手术证实为横结肠系膜裂孔疝1例;闭孔疝1例;盲肠旁疝1例;毕Ⅱ式结肠前吻合术后输出段空肠疝入输入段空肠与横结肠系膜间隙6例;Miles术后盆底腹膜裂开所致内疝5例;Miles术后降结肠与侧腹壁形成的间隙致内疝4例;大网膜与乙状结肠造口肠壁粘连形成内疝1 例;1例在梅克尔憩室基础上发生炎性粘连形成腹内疝;因腹腔粘连带与腹膜、腹腔脏器、肠壁、肠与肠之间的孔隙改变形成内疝17例(48.7%)。

Early enteral nutritional supporting could exacerbate histopathological changes of acute pancreatitic rats;excrine function could be stimulated after EN through jejunum when patients undergoing pancreaticoduodenectomy;regarding the pancreato-surgery diseases,simply pursuing early EN will endanger the pancreatic tissue,rather than bring advantage: the cost is more than award.

过早的EN治疗加重了大鼠急性胰腺炎病理及微循环改变情况,胰十二肠切除术后患者经空肠给予肠内营养仍会刺激胰腺的外分泌功能,对于胰腺外科疾病而言,单纯追求早期肠内营养不但没有好处,而且增加胰腺风险,弊大于利。

The infection in the male millipedes (91.67%) was higher than that in the females (84.67%). In some cases, more than two species of different gregarines were found to have simultaneously parasitized a single millipede.

能寄生在砖红厚甲马陆肠内的簇虫可能多达七种,且在同一只马陆个体的肠道中可同时被至少两种以上不同的簇虫所寄生。

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