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Through all this test analyse Pathogenicity and Immunological status of ALV-J Inner Mongolia strain, the result showed the infected chickens began to have pathological change of Myelcytomatosis at 3-week: the main pathological changes of acidophile myelocyte were found in bone marrow and between cardiac muscle fibers,and there were many granules in the hyalotome.This kind of oncocyte proliferated in every tissue at different amount, but the cells that proliferated in bone marrow, cardiac muscle fiber, oarium were much more than other tissue, and they often developed neoplasma. At same condition,there were no abnormalty advent in control group, In immunological aspect: the increase of lymphokine and ANAE positive cells showed cell-mediated immunity was strengthend during antineoplastic infection; the emergence of ALV-J antibody of ELISA suggest there was humoral immunity exist at the same time.

结果显示:脾脏PCR检测结果表明1、2两实验组均有阳性病例出现,而对照组全部为阴性,说明实验鸡体内已有ALV-J内蒙株感染;接种病毒后3周龄开始出现骨髓细胞瘤病的病理变化:肝脏、脾脏有程度不同的肿大,镜下观察,骨髓内最早出现了与骨髓细胞相似、形态基本一致的大型圆形或椭圆形、胞核较大多为椭圆形、胞浆内含有大量嗜酸性圆形颗粒的髓细胞样瘤细胞增生,随后通过血流瘤细胞可转移到肝脏、心肌、卵巢或睾丸等组织并形成肿瘤性病灶,而对照组没有出现明显病变;免疫状态方面:以脾脏淋巴因子和ANAE阳性细胞增多说明细胞免疫在抗肿瘤感染过程中增强,ELISA检验实验鸡抗体出现阳性的结果表明同时也存在着体液免疫。

Some physicochemical therapy as well as nake hepatocytes transplantation can't correct metabolic disarrangement because of severe hepatic diseases, ALF is characteristic of more complications and easily resulting in multiple organs dysfunction , and even multiple organs failure as well as higher mortality. transplant technique of encapsulated hepatocytes can inhibit immune rejection, and quarantee hepatocytes survival, the technique provides a new therapeutic method for ALF.

由于肝脏功能较复杂,一些利用物理、化学方法及裸肝细胞移植来代替肝脏解毒功能,但不足以纠正严重的肝病所致的代谢紊乱,易致多脏器功能障碍甚至衰竭,并发症多,死亡率高;而微囊化肝细胞移植技术,既可阻断受体的免疫排斥反应,又保证移植的肝细胞在体内长期存活,为急性肝衰治疗提供新的治疗方法。

Chapter Three describes the expression profiling analysis of human fetal livers in hematogenesis, normal adult livers and HCCs using cDNA arrays containing 5612 gene/clusters.

论文的第三章是利用含5612个基因/clusters的cDNA array,对人的造血期的胚胎肝脏,成年正常肝脏及HCC组织的基因表达谱进行了比较。

The liver oval cell line WB-F344 derives from adult normal Fisher 344 male rats. It's a kind of liver infantine epithelial cells and has characteristics of liver stem cells. Many studies in vitro and in vivo imply that it has the role as precursor cells of hepatocacinoma, which indicates its function in hepatocarcinogenesis.

肝卵圆细胞株WB-F344来自正常成年同基因Fisher344雄性大鼠,是一种肝脏幼稚上皮细胞,具有肝脏干细胞的性质,体内、外的许多研究表明,它与肝癌的发生有一定的关系,具有肝癌前体细胞的作用。

Affect on the liver pathological state after XIEZHIPING treated: the golden hamster hepatic tissue morphous structure of normal control was normal, which had regular hepatic lobules and no lipid droplet;that of model control manifested diffuse heavy adipose degeneration and heavy ballooning degeneration with inflammatory cell infiltrate which mainly composed of lympholeukocyte;that of high dose group showed midrange ballooning degeneration with chronic inflammatory cell infiltrate which mainly composed of lympholeukocyte and plasmocyte;that of media dose group indicated slight focus ballooning degeneration with a small quantity normal hepatic cells in some locals;that of low dose group appeared midrange adipose degeneration with a few lympholeukocyte cell infiltrate in the parts of central veins and port area.

泻脂平治疗后对肝脏病理状况的影响:空白对照组金黄地鼠的肝组织形态结构正常,肝小叶规则,无脂滴发现;模型对照组肝脏弥漫性重度脂肪变性,发生重度气球样变,伴见以淋巴细胞为主的慢性炎性细胞浸润;泻脂平高剂量组肝细胞呈现中度气球样变,伴见以淋巴细胞、浆细胞为主的慢性炎性细胞浸润;中剂量组肝细胞轻度灶性气球样变,局部可见少量正常肝细胞;低剂量组肝细胞呈中度脂肪变性,可见中央静脉及汇管区些许淋巴细胞浸润。

Affect on the liver pathological state afterXIEZHIPING treated: the golden hamster hepatic tissue morphous structureof normal control was normal, which had regular hepatic lobules and nolipid droplet: that of model control manifested diffuse heavy adiposedegeneration and heavy ballooning degeneration with inflammatory cell infiltrate which mainly composed of lympholeukocyte; that of high dosegroup showed midrange ballooning degeneration with chronic inflammatorycell infiltrate which mainly composed of lympholeukocyte and plasmocyte;that of media dose group indicated slight focus ballooning degenerationwith a small quantity normal hepatic cells in some locals; that of lowdose group appeared midrange adipose degeneration with a fewlympholeukocyte cell infiltrate in the parts of central veins and portarea.

泻脂平治疗后对肝脏病理状况的影响:空白对照组金黄地鼠的肝组织形态结构正常,肝小叶规则,无脂滴发现;模型对照组肝脏弥漫性重度脂肪变性,发生重度气球样变,伴见以淋巴细胞为主的慢性炎性细胞浸润;泻脂平高剂量组肝细胞呈现中度气球样变,伴见以淋巴细胞、浆细胞为主的慢性炎性细胞浸润;中剂量组肝细胞轻度灶性气球样变,局部可见少量正常肝细胞;低剂量组肝细胞呈中度脂肪变性,可见中央静脉及汇管区些许淋巴细胞浸润。

Based on force feedback device named PHANTOM produced by SensAble Inc.,this system makes use of virtual reality technology to implement the surgery procedures of liver and tissue.

该系统基于SensAble公司的PHANTOM力反馈设备,利用虚拟现实技术实现肝脏手术过程中有关肝脏及其内部组织的多种手术操作,提供真实的视觉反馈和力反馈,其有良好的实时性。

The toxical effects of nonylphenol ethoxylates and nonyiphenol were studied with EROD in liver of carp as biomarker under external condition. These two tested substances all had activation on EROD enzyme in liver of carp. Under definite range of concentrations, with the affecting rule of inhibiting at high concentration and inducing at low concentration.

在离体条件下,以鲤鱼肝脏EROD酶为生物标志物研究了壬基酚聚氧乙烯醚及壬基酚的毒性效应结果表明,在一定的浓度范围内,2种受试物对鲤鱼肝脏EROD酶均有激活作用受试物浓度对EROD酶的活性的影响规律为高浓度时抑制,低浓度时诱导。

Dr. Norbert Stefan and colleagues at the University of Tubingen in Germany closely examined 314 people, using magnetic resonance imaging to look at precisely how much body fat they had and where it was.

人体摄入的脂肪食物过量,肝脏代谢脂肪的功能下降或转运能力降低,人的活动量减少,脂肪消耗量减少,都会造成肝脏脂肪的堆积,关键要找到主要矛盾,抓住主要矛盾对症治疗才能事半功倍。

Contrast-enhanced ultrasound has been widely used in the imaging of liver and other organs such as kidney, pancreases, spleen, prostate, ovarian, uterus as well as abdominal trauma, showing promising values in the diagnosis and differential diagnosis of various diseases.

近年发展起来的微泡超声造影剂已经在临床中得以应用,超声造影也已广泛用于肝脏及肝脏以外器官的显像,如肾脏、胰腺、脾脏、前列腺、卵巢、子宫和腹部外伤,并在多种疾病的诊断和鉴别诊断中显示出日益增长的潜力。

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