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Objective To explore the effect of high serum concentration of bile acids on energy metabolism of liver.Methods Bile acids were continously infused into the Wistar rats to simulate the serum concentration change of patients with obsturctive jaundice.Serum bile acids concentration,arterial blood ketone body ratio and energy charge of liver were determined.Results Aterial blood ketone body ratio and energy charge of liver decreased with the increase of serum bile acids concentration.Conclusion High serum concentration of bile acids plays an important role in hepatic fumction injury caused by biliary obstruction.

目的 探讨高胆汁酸血症单一因素对肝脏能量代谢的影响方法经Wistar大鼠颈内静脉持续给予外源性胆汁酸,升高其外周血清中胆汁酸浓度,模拟阻塞性黄疸患者外周血清中胆汁酸的变化规律,观察腹腔动脉血酮体比值及肝组织能荷变化,时间一周结果随外周血清中胆汁酸浓度的升高,腹腔动脉血酮体比值、肝组织能荷均呈进行性下降结论高胆汁酸血症时肝脏能量代谢受损,表明在阻塞性黄疸患者肝功能损害中高胆汁酸血症起了重要作用

There is an increase of CXCR6 expression in LILs. In hepatic infiltrating lymphocytes, the number of PD-1+CXCR6+CD3+T cells is increased compared with the number of these cells in PBLs.

在肝脏浸润淋巴球中,化学性激素接受器CXCR6表现量也有显著的增加,同时在具化学性激素接受器CXCR6表现的肝脏浸润淋巴球中,带有PD-1分子的细胞数也有增加。

Originally, doctor had to do it by himself from first image to the last. It was inefficient and needed a lot of time. So, how to use computer technology to extract liver contour automatically is an important research field.

肝脏边界的确定是定量分析的前提,原先医生必须对肝CT序列中的每一幅图像都要手工确定肝脏边界,这耗时费力,效率也不高。

The heat stress response is associated with the induction of heat shock protein.

研究预处理的机制是为了给肝移植、肝脏手术等提供更好的肝脏保护方法。

For example, victims of the Death Cap, one of the deadliest mushrooms, may not feel anything _(3)_ during the first 12 hours. But beginning in the 13th hour, the victim may start to have violent stomach pains and gas. Vomiting and diarrhea follow shortly. And finally, their liver and kidneys fail and they have only a 50 percent chance of survival. The survivors are spared but have to _(4)_ permanent liver and kidney damage for the rest of their days.

例如,误食一种名为『毒鹅膏』的致命毒菇,前十二个小时可能不会有任何异状,但第十三个小时开始,中毒者会开始产生剧烈腹痛和胀气,接着上吐下泻,到最后会导致肾脏和肝脏衰竭,中毒者只有百分之五十的存活率,但幸存者必须终身饱受肾脏和肝脏损伤。

Objective To investigate the characterization of hepatic space-occupying lesions on gray-scale contrast-enhanceduhrasonograp-hy.

目的 探讨动态灰阶超声造影在不同性质的肝脏占位性病变中增强特征,为肝脏占位性病变的诊断及鉴别诊断提供依据。

Of 9 female recipients of livers from male donors had chimerism in their allografts and extrahepatic tissues, according to in-situ hybridisation and molecular techniques 10 to 19 years posttransplantation.

肝移植后10-19 年,根据原位杂交和分子技术,9 名接受男性肝脏移植的女性受体的肝脏及肝外组织均存在嵌合现象。

The liver is a complex metabolically active organ, particularly susceptible to shock, and liver failure carries a high mortality rate.

肝脏是一个代谢功能复杂且重要的器官,各类休克常导致肝脏衰竭,同时合并极高的死亡率。

Experimental Center of National Level One, Hubei Traditional Chinese Medica l College, Wuhan 430061)Abstract To investigate the protective effects of Jiaweisinisa n on acute liver injury induced by intraperitoneal injection of D-ga lac-tosamise, serum superoxide dismutase, malondialdehyde , glutathioe contents were measured. The pathological changes of liver wer e observed simultaneously. The results showed that JWSNS could decrease serum MD A content, but increase serum SOD and GSH activities in acute liver injury induc ed by D-GalN. It was also found that JWSNS could alleviate the degeneration and necrosis of the hypatocytes.

为研讨加味四逆散防治肝损伤的作用机理,通过动物试验,先用加味四逆散预防给药,再采用D-氨基半乳糖造成大鼠急性肝损伤模型,然后检测大鼠血清超氧化物岐化酶、丙二醛、还原型谷胱甘肽水平,同步观察该方对急性肝损伤大鼠体内脂质过氧化反应及肝脏病理改变的影响,结果表明该方可明显升高大鼠血清SOD、GSH水平,降低MDA水平,肝脏病理学检查亦表明该方使肝细胞变性坏死程度减轻。

This very first application of hyperpolarized 13C NMR spectroscopy in the liver illustrates that this technique can be used to monitor in vivo gluconeogenesis on the time scale of seconds and provides impetus for using this technology in more advanced imaging studies to investigate the state of hepatic gluconeogenesis during a variety of pathophysiologies.

本研究首次在肝脏中采用极化13C NMR光谱学检测技术,并表明此技术可在以秒计算的时间范围内对糖异生进行监测,而且这将有助于在不同病理生理学状态下对肝脏糖异生进行更为先进的影像学研究。

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As she looked at Warrington's manly face, and dark, melancholy eyes, she had settled in her mind that he must have been the victim of an unhappy attachment.

每逢看到沃林顿那刚毅的脸,那乌黑、忧郁的眼睛,她便会相信,他一定作过不幸的爱情的受害者。

Maybe they'll disappear into a pothole.

也许他们将在壶穴里消失

But because of its youthful corporate culture—most people are hustled out of the door in their mid-40s—it had no one to send.

但是因为该公司年轻的企业文化——大多数员工在40来岁的时候都被请出公司——一时间没有好的人选。