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Cornell researcher Michael Shuler knew that a drug's effect depends less on chemistry than on the way it navigates the obstacle-course of the body's organs: being broken down by the liver, absorbed by the intestines and held onto by fat.

康奈尔大学的研究人员麦克。舒勒深知药品在人体内受到各种器官的重重干扰,这对药品效用的影响大于药品自身的化学作用。这些干扰包括肝脏会分解药品,大小肠会吸收药品,脂肪则会阻滞药品。

The second part of the study examined the distribution of type Ⅰ and Ⅲ collagens, fibronectin and laminin in murine liver using protein A gold silver tealnique.

研究的第二部分建立了光镜水平的葡萄球菌A蛋白金银染色法并将其运用于对肝脏基质抗原FN和LN的免疫细胞化学研究,获得了优于免疫荧光法和免疫酶法的结果。

AIM: To study the possible hepatotoxicity of Wistar rats induced by sodium dodecyl sulfate.

目的:探讨十二烷基苯磺酸钠对Wistar大鼠肝脏的影响。

AIM摘要: To study the possible hepatotoxicity of Wistar rats induced by sodium dodecyl sulfate.

目的摘要:探索十二烷基苯磺酸钠对Wistar大鼠肝脏的影响。

This doesn't speak well for myself, but without further delay over time I can cause long term damage to the liver.

这不也是为自己说话,但我可以毫不拖延时日造成长期损害肝脏

Stephen Spindler and his colleagues from the University of California at Riverside have found that some of an elderly mouse's liver genes can be made to behave as they did when the mouse was young simply by limiting its food for four weeks.

Stephen Spindler和他在Riverside的加利福尼亚大学的同事们已经发现,一只高龄老鼠只要连续四周限制它进食,它的某些肝脏基因就会变得和衰老前一样充满活力。

And There was no serious complication;②In the course ofinterventional therapy, Direct portal vein angiography demonstrated vena coronaria ventriculi(100%)andgastricveins(65.26%)andvenagastricaposterior38.43%, Angiography demonstrated venacoronariaventriculi communicate esophagus varicose veins, gastric veins and vena gastrica posterior communicategastric varicose veins. vena coronaria ventriculi had only a small percentage of double vein, about30.57%. The sites of vena coronaria ventriculi arising from the portal vein, splenic vein, portosplenic junction, were found in 52.06%、27.39%、20.55% respectively.③12 extrahepaticprotosystemic shunts were found in these patients. Include gastro-nephrosshuntof 3 cases, 7 caseswere splenetic- nephros shunt and 2 cases shown recanalization of umbilical vein .④The averageportal pressure before and after the procedure were 3.87±1.82kPa and 3.64±1.14kPa in 73patients, but to the time of rebleeding, it was 3.96±0.23kPa in the 11 cases.⑤There werethree kinds of variceal outcome: disappearance (54,low degree (19).⑥Spearman logisticanalyse and ANOVAtest shown liver function class, variceal degree of the splenic necrosis area,the blood direction in portal vein before operation and remain small collateral routes were thesignificant factors concerning outcome of varices.⑦The bleeding volume and portalhypertensive gastropathy are main risk factors of rebleeding.⑧The course of livercirrhosis is the risk factor of survival and extrahepatic portosystemic shunt , fine varices are thebeneficial factors to survival.⑨During all cases'followed-up data, the 1, 2, 3, 4, 5 yearcumulative survival rates and rebleeding rates were 17.81%, 28.77%, 38.36%, 43.84%, 47.95%and93.15%,91.78%,86.30%,83.56%,80.82%respectively. Conclusion The interventional disconnection treatment for liver cirrhosis and portalhypertension was designed suitability. It rapidlycontrol bleeding,butpressure of portal vein was notobvious high, perfusion was not low .it was compared with surgery therapeutic that interventionaldisconnection treatment was safe and had a significant clinical effect to hemorrhage and preventfrom rebleeding.

结果:①术后一过性发热62例(84.9%),腹痛腹胀48例(65.8%)是介入断流术常见的并发症,未发生严重并发症;②门静脉造影显示胃冠状静脉、胃短静脉和胃后静脉的曲张分流的出现率是100%、65.26%和38.34%;显示食管静脉曲张主要由胃冠状静脉供血,胃静脉曲张主要由胃短静脉和胃后静脉供血;胃冠状静脉大多数为单支,少数为双支,其双支的出现率分别为30.57%;胃冠状静脉开口于门静脉主干的为52.06%,开口于脾静脉主干的为27.39%和开口于门脾静脉交汇处的为20.55%;③发现胃肾分流3例,脾肾分流7例、腹膜后门腔静脉分流2例,以及CTA检查发现脐静脉开放者2例;④73例患者介入断流术前和术后平均自由门静脉压力分别为3.87±1.82kpa和3.64±1.14kpa,前后比较存在显著性差异;11例再次介入手术患者的术前、术后和复发后的自由门静脉压力分别为4.02±0.24kpa、3.82±0.25kpa和3.93±0.23kpa ,前后比较发现首次术前与术后存在显著性差异,首次术前和复发出血术前门静脉压力比较无显著性差异;⑤介入术后复查曲张静脉转归基本消失54例,轻度19例;⑥Spearman相关分析和Logistic多因素回归分析,肝功能分级、静脉曲张程度、门脉血流方向和残存小侧支四个因素对曲张静脉转归有影响;Spearman相关分析和Logistic多因素回归分析门脉高压性胃病和出血量等因素对复发出血时间有影响;⑦COX回归分析,门体分流和曲张静脉转归两个因素对术后生存有影响;⑧术后随访6-70月,1、2、3、4、5年的累计复发出血率和累计生存率分别为17.81%、28.77%、38.36%、43.84%、47.95%和93.15%、91.78%、86.30%、83.56%、80.82%;结论:介入断流术治疗门脉高压食管胃底静脉曲张有独特的优点,可以快速直接控制曲张静脉出血而门静脉压力无显著增高,保证了肝脏灌注;与外科分流术相比适应证广、损伤轻、术后恢复快,不易遗漏曲张静脉;肝功能分级、曲张静脉程度、门脉血流方向和残存侧支血管对食管胃曲张静脉转归有影响;门脉高压性胃病对复发出血时间有影响;门体分流和曲张静脉转归对生存时间有影响。

The results showed that a large amount of Actinobacillus pleuropneumoniae with gram negative infections could be seen in the secretion of bronchus; There were congestion in liver, necrosis, hemorrhage, fibrosis with neutrophils and macrophage infiltrating in lung tissue, necrotic splenitis in spleen, and hemorrhagic lymphadenitis in lymph node.

结果表明;在支气管分泌物涂片中含有大量呈革兰氏阴性的胸膜肺炎放线杆菌;肝脏淤血,肺组织坏死、出血、显著纤维化及嗜中性粒细胞和巨噬细胞浸润;脾脏呈坏死性脾炎变化,淋巴结呈出血性淋巴结炎变化。

In the diet, deprivation should be salted fish, bacon, ham, sausage, dried small shrimps, salted shrimp, etc., Prince, smoked, fried food, eating green onions, ginger, pepper and other irritating foods, and more intake of fresh fruits, vegetables and the role of faded pigments winter melon, sponge gourd, tomato, potato, cabbage, cauliflower, Fresh, hawthorn, orange, lemon, and soy products such as animal liver, the elimination of these foods have a certain Chloasma a supporting role.

在饮食方面,应少食咸鱼、咸肉、火腿、香肠、虾皮、虾米等腌、腊、熏、炸的食品,少吃葱、姜、辣椒等刺激性食品,多摄取新鲜水果、蔬菜和具有消退色素作用的冬瓜、丝瓜、西红柿、土豆、卷心菜、花菜、鲜枣、山楂、橘子、柠檬、豆制品和动物肝脏等,这些食品对消除黄褐斑有一定的辅助作用。

A traditional tune revealing another aspect of the suona is the Sprig of Blossoms.

检查时肝脏的结节可能有启示性。

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With Death guitarist Schuldiner adopting vocal duties, the band made a major impact on the scene.

随着死亡的吉他手Schuldiner接受主唱的职务,乐队在现实中树立了重要的影响。

But he could still end up breakfasting on Swiss-government issue muesli because all six are accused of nicking around 45 million pounds they should have paid to FIFA.

不过他最后仍有可能沦为瑞士政府&议事餐桌&上的一道早餐,因为这所有六个人都被指控把本应支付给国际足联的大约4500万英镑骗了个精光。

Closes the eye, the deep breathing, all no longer are the dreams as if......

关闭眼睛,深呼吸,一切不再是梦想,犹如。。。。。。