肝胃的

The heart,liver,spleen,lung,kidney,stomach and intestines of one agonal Cistoclemmys flavomarginatas were examined under transmission electron microscope.The results showed that a kind of short-stick bacteria were detected in heart,liver,spleen and kidney.

利用电子显微镜，对一只濒死黄缘盒龟的心、肝、脾、肺、肾、胃和肠道进行了检查，在心、肝、脾、肾均发现一种短杆状细菌感染，受染器官均出现明显的病理变化，如线粒体、高尔基体和内质网均肿大变形。

Using the immunohistochemical technique, nerve cell bodies and fibres immunoreactive to the anti-Met-enkephalin sera were observed in the cerebral ganglia, pedal ganglia, visceral ganglia, inspect ganglia and coat ganglia of Octopus ocellatus. Met-ENK immunoreactivity was also localized in the mouth, esophagus, craw, stomach, stomachic caecus, the epithelium of the intestines, rectum, sialoid gland, liver, branchia, branchia gland, ventricle, branchial heart, kidneys, ovary, fallopian tube, back of mantle, abdomen of mantle, wrist, membrane of wrist, funnel, and immunocytes of Octopus ocellatus.

免疫组织化学定位结果表明：(1)在短蛸的脑神经节、足神经节、脏神经节、视神经节、外套神经节、口球、食道、嗉囊、胃、胃盲囊、肠、直肠、前唾液腺、后唾液腺、肝胰脏、鳃、鳃腺、心室、鳃心、肾静脉腺质附属物、卵巢、输卵管腺、外套膜背面、外套膜腹面、腕、腕间膜、漏斗中检测到呈不同阳性反应的Met-ENK分子。

METHODS: Liver fibrosis models were established in 24 SD rats by intragastric administration (7 g/kg) of alcohol (56°, 560 mL/L) every morning, and 10 normal rats served as controls. The rats in model group were killed by exsanguination from femoral vein at 4, 12 and 24 wk. Pathological changes of liver tissues in rats were identified by Masson staining, and the expression of VEGF mRNA was detected by semiquantitative reverse transcription-polymerase chain reaction.

56度的白酒(560 mL/L)平均以7 g/kg的剂量每日早晨灌胃一次制备肝纤维化模型，灌胃4 wk、12 wk及24 wk采用股静脉放血法分别处死大鼠，观察肝脏病理变化并采用半定量逆转录聚合酶链反应检测VEGF mRNA的表达。

Firstly, normal mice was given orally by SM(qd×2d), and the dysbacteriosis were caused in them ,and then they were given orally by STM,these mice were formed experimental salmonellosis models ,finally these salmonellosis models were treated by bifidobacterium ,and count respectively the cfu/g of STM number in the mice excrement during different time of therapy,detect the index numbers of liver and spleen respectively, detect content of TNF-a in blood and in spleen respectively.

先用硫酸链霉素给正常小鼠灌胃2d，出现菌群失调症状，再用STM灌胃造成小鼠STM感染，使用两岐双岐杆菌液干预治疗STM感染小鼠，检测不同治疗时间各组小鼠粪便STM菌落数、肝脾指数、血及脾中TNF-a的含量。采用SPSS12.0统计软件包进行数据处理分析，统计学方法采用双因素重复测量资料的方差分析、单因素随机化设计的方差分析、卡方检验、多组均数比较的非参数秩和检验。结果：随着治疗天数的增加，STM菌落数逐渐减少，未干预组、生理盐水组及双歧杆菌组比较结果均为P＜0.01；组间比较，双歧杆菌组STM数下降最快。

But injury of normal tissue is one of important factors which have to stop killing tumor cell thouoghly, in all process of tunor therapy Since the injury all over argans and cells of the body by free radical, especially significant side-effect to heart via ariblastine ,is universally accepted, we chose Adriamycin as chemical therapy medicine in our study.

由于阿霉素具有比较公认的自由基周身性损伤、特别是对心脏损伤的突出副作用，因此，本课题选择阿毒素作为化疗药物，模型制作采用在SD大鼠肝表面种植Walker－256瘤细胞株，于种瘤后第11天按2mg~(-1)kg体质量给单纯化疗组和化疗保护组的大鼠腹腔注射阿霉素，正常对照组和荷瘤对照组按相同比例腹腔注射生理盐水；同时，每日上午按0.5ml/100g体质量经胃给于化疗保护组抗氧化剂混合液，其余各组每日给于相同剂量的三蒸水；下午按0.1ml/100g体质量经胃给于化疗保护组维生素E溶液，其余各组每日给于相同剂量的处理过的油。

But injury of normal tissue is one of important factors which have to stop killing tumor cell thouoghly, in all process of tunor therapySince the injury all over argans and cells of the body by free radical, especially significant side-effect to heart via ariblastine ,is universally accepted, we chose Adriamycin as chemical therapy medicine in our study.

由于阿霉素具有比较公认的自由基周身性损伤、特别是对心脏损伤的突出副作用，因此，本课题选择阿毒素作为化疗药物，模型制作采用在SD大鼠肝表面种植Walker－256瘤细胞株，于种瘤后第11天按2mg~(-1)kg体质量给单纯化疗组和化疗保护组的大鼠腹腔注射阿霉素，正常对照组和荷瘤对照组按相同比例腹腔注射生理盐水；同时，每日上午按0.5ml/100g体质量经胃给于化疗保护组抗氧化剂混合液，其余各组每日给于相同剂量的三蒸水；下午按0.1ml/100g体质量经胃给于化疗保护组维生素E溶液，其余各组每日给于相同剂量的处理过的油。

The occuurrence of depression is consanguineously related to the weak physique, diffidence, and stagnation of liver qi. As for the pathogenesis, Depression usually has relation with heart, brain, liver, spleen, stomach, the three warmers, kidney, and especially liver, spleen and stomach. The stagnation of qi is the most important character of this disease.

病机方面，认为其病位主要在心、脑，但其发生与肝、脾、胃、三焦、肾和胆等脏腑有关，尤其是与肝脏和脾胃密切相关，气机郁滞是本病最重要的病理特征；在病机转化上，本病大多具有肝失疏泄，气机郁滞，日久郁而化火，导致正虚邪盛的特点。

PartⅡ:Effect of bicyclol on hepatocyte apoptosis in alcohol-intoxicated mice and related mechanismsThree consecutive intragastric administration of alcohol(6g/kg)in 12h interval resulted in an obvious liver injury and inflammation in mice,as indicated by the elevation of serum alanine transaminase(2.2 fold of control),increased hepatic COX-2 protein expression(2.2 fold of control),as well as liver pathological changes characterized by myelonic degeneration,vacuolar degeneration and inflammatory infiltration.

双环醇对酒精中毒小鼠肝脏细胞凋亡的保护作用及机制研究小鼠连续三次酒精(6g/kg)灌胃后可导致明显肝损伤，变现为血清ALT水平升高(为对照组的2.2倍)，肝脏炎症相关蛋白环氧合酶-2(cyclooxygenase-2，COX-2)表达增加(为对照组的2.2倍)，肝组织出现髓样变性、小空泡变性和炎性细胞浸润。

Treated with baicalin by oral administration, the content of glutamic pyruvic transaminase and glutamic oxalacetic transaminase could be degraded in the Alcoholic fatty liver of rats, and it had evident protection for the rats and mice'Alcoholic fatty liver.

黄芩苷灌胃给药后，可降低肝损伤小鼠及大鼠谷丙转氨酶和谷草转氨酶含量，对小鼠及大鼠肝损伤均有明显的保护作用。

Methods: Liver injure rat models were made by alcohol, the high-dose and low-dose ZhiGanQing Capsule were continuously watered by for 8 weeks, the contents of AST、ALT and TG were detected separatedly, and the hepatic pathology was observed too.

采用白酒复制大鼠肝损伤模型，脂肝清胶囊按高、低剂量灌胃，连续8周，测定血清天冬氨酸转氨酶、丙氨酸转氨酶及甘油三酯的含量，并观察肝脏的病理组织学改变。

It has been put forward that there exists single Ball point and double Ball points on the symmetrical connecting-rod curves of equilateral mechanisms.

从鲍尔点的形成原理出发，分析对称连杆曲线上鲍尔点的产生条件，提出等边机构的对称连杆曲线上有单鲍尔点和双鲍尔点。

The factory affiliated to the Group primarily manufactures multiple-purpose pincers, baking kits, knives, scissors, kitchenware, gardening tools and beauty care kits as well as other hardware tools, the annual production value of which reaches US$ 30 million dollars.

集团所属工厂主要生产多用钳、烤具、刀具、剪刀、厨具、花园工具、美容套等五金产品，年生产总值3000万美元，产品价廉物美、选料上乘、质量保证，深受国内外客户的青睐