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The duct is diffusingly narrow. The bile duct wall is stiff without flexibility, taking the shape of leaden tube. The normal intrahepatic bile duct is deprived of its "willow"-style softness and smoothness. The intrahepatic bile duct branches are to scarce to reach the edge of the liver, taking the shape of "withered arborization" or "pruned trees".

胆管呈弥漫性狭窄,胆管壁僵硬,缺乏弹性,呈铅管状,失去正常肝内胆管的"垂柳"样的柔软、平滑的表现,肝内胆管细支显得稀少而达不到肝脏的边缘,呈所谓的"枯枝"或"剪枝"状。

Sanchez ET ,Botella LM ,Velasco B ,et al. Synergistic cooperation between hypoxia and transforming growth factor2beta pathways on humanvascular endothelial growth factor gene expression. J Biol Chem ,2001,19,276:38527238535.[3] Blancher C,Moore JW,Talks kl,et al.Relationship of hyposia-inducible factor HIF-1alpha expression to vascular endothelial growth factor I nduction and hypoxia survival in human breast cancer cell lines.

肝细胞癌中缺氧诱导因子-1α、热休克蛋白70的表达】;综上所述,肝细胞癌发生后,由于血供不足诱导HIF-1α过度表达,应激状态下产生的HSP70通过减轻缺血性损伤,增加毛细血管的生成及减轻细胞凋亡等途径使肿瘤细胞的增殖、移行加快,促进恶性肿瘤的生长、浸润和转移,使肿瘤细胞在适应缺氧、能量代谢、细胞凋亡及转移中起重要作用。

Presented with early artery enhancement and immediate wash out ,Two cases presented with wash in quickly and wash out slowly .The enhancement pattern of 36 liver metastatics cases was divided into the little blood provides group and the much blood provides group . The 5 cases of haemangioma were enhanced centripetally in portal phase and washed out after several minutes without arterial enhancement.

通过造影后的表现还可明确提示以下几个方面:(1)肿块内的坏死区;(2)在延迟相发现了肝内小转移灶,从而改变了临床治疗方案;(3)滋养动脉的显示;(4)门脉内栓子的鉴别诊断。36个转移性肝癌病灶分为少血供转移癌组和多血供转移癌组。6例肝血管瘤中5例均表现为向心性环行持续缓慢充填,另一例9mm的小血管瘤表现为完全、快速向心填充。

Methods The clinical data of 132 patients with liver tumors received transcatheter chemoemb olization therapy were reviewed, including the conditions of cholecyst before em bolization and the methods of embolization, related to the occurrence of cholecy stitlis after embolization.

回顾132例接受肝动脉化疗性栓塞治疗的肝肿瘤患者的临床资料,对栓塞前造影中胆囊的显影情况、采用的栓塞方式和术后有无胆囊炎的发生进行相关性分析。

The many dark clusters of cells in the hepatic parenchyma are islands of extramedullary hematopoiesis typical for fetal liver.

肝实质内的许多色暗的成串的细胞是髓质外的岛状肝细胞增生。这是胎儿肝脏的典型表现。

Results:Normal rats as the donator of serum, using methanolic extract of CWC, 10 times equivalent dose for adults every day, intragastric administration twice a day of 8-hour interval, keeping on 3 days, hemospasia after 2 hours of the last administration was the better preparative method of the serum containing drug.

建立CCl4诱导的原代培养大鼠肝细胞损伤模型,大鼠为含药血清供体,以含药血清对损伤肝细胞增殖及丙氨酸氨基转移酶泄漏的影响两个指标,结合含药血清中五味子乙素的含量测定,分别采用单因素考察、多因素的正交试验,优选含药血清的制备方法,并确定体系中血清添加量。

This review aims to discuss the category of hepatic stem cells, the methods on induction, isolation, culture and identification after transplantation in order to summarize the relationship between hepatopathy and clinical application.

目的:肝干细胞的研究已成为近年的热点,本文检索了肝干细胞的分类、诱导、分离、培养及移植后的鉴定方法,分析了它们与肝病的关系和临床应用前景。

Liver transplantation for hepatics B is going down; however, due to the effectiveness of new therapies, now people don't need to die or undergo transplantation from HBV.

由于新的治疗药物的作用,乙型肝炎造成的肝移植的需求在下降,目前患者不会因为乙型肝炎而需要遭遇死亡和肝移植了。

In a word, this lentivirus vector can help us study the differentiation mechanism of liver progenitor cells, and scan the molecules which can do a help in differentiation.

总之,这一载体的成功构建将为研究肝干/祖细胞的分化提供了便捷的工具,同时也有助于筛选可诱导肝干/祖细胞定向分化的分子。

PartⅡExperimental Study on Acute Hypatocyte Necrosis and Apoptosis with MRI, DWI and MRS Objective: To demonstrate the ability and value of MR imaging, diffusion-weighted imaging, and MR spectroscopy in detecting and characterizing necrosis and apoptosis in vivo with a comparison to the pathology after establishment of hepatic necrosis and apoptosis animal model by different surgical ligations of hepatic blood supply vessels.

目的:通过手术结扎的方法建立大鼠肝细胞坏死和凋亡的动物模型,将不同时间点的MRI、DWI和MRS检测结果与病理学所见进行对照研究,以评价MRI、DWI及MRS在检测及鉴别肝细胞凋亡和坏死两种病理改变的能力与价值。

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As she looked at Warrington's manly face, and dark, melancholy eyes, she had settled in her mind that he must have been the victim of an unhappy attachment.

每逢看到沃林顿那刚毅的脸,那乌黑、忧郁的眼睛,她便会相信,他一定作过不幸的爱情的受害者。

Maybe they'll disappear into a pothole.

也许他们将在壶穴里消失

But because of its youthful corporate culture—most people are hustled out of the door in their mid-40s—it had no one to send.

但是因为该公司年轻的企业文化——大多数员工在40来岁的时候都被请出公司——一时间没有好的人选。