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In this article, we used automotive immunohistochemical stainer to check the expressions of HBsAg and HCV antigens in 100 cases of HCC and their adjacent tissues, mean while, we checked their histological activity index and hepatic fibrosis degree. We also used radioimmunoassay to detect serum levels of 4 serum fibrosis markers and serum AFP levels in these cases. Immunofluorescence labeling and flow cytometry were used to check the T-cell subpopulations and the activity of NK cells of these 100 cases. Then the correlations among these factors were studied.

本文采用全自动免疫组化仪对100例肝癌组织及癌旁组织中的HBsAg、HCV抗原表达进行了标记,同时对其进行肝组织活动指数、纤维化分期;同时采用放射免疫测定方法检测同期血清透明质酸、Ⅲ型前胶原蛋白、层粘连蛋白和Ⅳ型胶原蛋白等四项血清肝纤维化标志物和血清甲胎蛋白水平;采用免疫荧光标记技术和流式细胞仪对T细胞亚群及NK细胞活性测定,对各项指标的相关性进行系列对比研究。

Hepatic stellate cells is playing the central role in the pathogenesis of liver fibrosis.

肝星状细胞在肝纤维化的发展过程中起着关键的作用。

While comparing with the applying the traditional therapy only, the combining appliance of Ruangan No.1 and diuretics to the liver cirrhosis patients with ascites could significantly improve the clinical symptoms on total effective rate, regression time of ascites, improvement of liver function.

软肝一号合利尿剂治疗肝硬化腹水,在总有效率上,腹水消退时间上以及肝功能的改善上都明显优于单纯护肝利尿的常规治疗。

Following the treatment with Trillium Tschnoskii Maxim,ALT and AST activities and MDA content were significantly reduced and SOD activity was obviously increased in the mice of treating group.

结果 头顶一颗珠能明显降低CCl4致小鼠肝损伤血清ALT、AST值升高,降低肝组织匀浆中MDA的含量,增强SOD的活性。

Results The detective rates of symptoms as dizziness, sight descend, faintness for seeing, bleed to brush teeth and pain in liver area in the ease group were significantly higher than that in the control groups; The detective rates of lens turbidness, liver augment, Hb descend and abnormity of liver function were also significantly higher than that in the control group.

结果 接触组自觉症状中头昏、视力下降、视物模糊、刷牙出血、肝区疼痛5项的检出率明显高于对照组;体检项目中眼晶体混浊、肝大、血红蛋白降低、肝功能异常4项的检出率明显高于对照组。

Extract of Achillea millefolium L .can protect hepatocytes from injury and prevent the progress of hepatic fibrosis in rats,which may associate with that extract of Achillea millefolium L .

蓍草提取物对大鼠实验性肝损伤有一定程度的预防和治疗作用,具有一定的抗肝纤维化作用。

Methods The relation of fatty liver and cardiovascular disease, hypertension, diabetes mellitus, arteriorenal resist index was studied by analyzing 730 in over 40 years old fatty liver patients.

分析年龄40岁以上730例脂肪肝人群中冠心病、高血压病、糖尿病患病率,以及肾动脉阻力指数的变化与非脂肪肝人群的关系。

Radis Astragali has satisfactory effect on experimental fibrosis.The mechanism may be correlated with its affection on ICAM-1 in liver tissue.

黄芪有良好的抗肝纤维化作用,其机理可能与其抑制肝细胞中ICAM-1的表达有关。

There were significant differences of the incidences of 4 water-borne infectious diseases(cholera,hepatitis A,bacteroidal diarrhea and typhoid or paratyphoid)between former 5 years and later 5 years.The incidences of 4 water-borne infectious diseases except bacteroidal diarrhea showed downtrends year after year in 10 past years.By relativity analyzing,there were negative correlations between overall incidences of 4 water-borne infectious diseases and the qualification rate of drinking water coliform group,between the incidence of hepatitis A and drinking water coliform, between the incidence of typhoid or paratyphoid and drinking water total plate countand between the incidence of typhoid or paratyphoid and drinking water coliform.

改水前后各五年霍乱、甲肝、菌痢、伤寒副伤寒等四类主要介水传染病总发病率的差异有显著性,四类主要介水传染病的总发病率与饮用水大肠菌群合格率之间、甲肝发病率与饮用水大肠菌群合格率之间、伤寒副伤寒发病率分别与同期饮用水细菌总数和大肠菌群指标合格率之(来源:A1eBC3737论文网www.abclunwen.com)间呈负相关。

Betulin has obviously protective effects on alcoholic liver injury in rats.The mechanism may be the induced decrease of lipid peroxide.

白桦脂醇能抑制酒精诱导脂质过氧化反应对肝组织的损伤,对酒精性肝损伤有明显的保护作用。

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