肝的

Among 24 cases,no epiphyte and virus infection,no angiostegnosis,no biliary passage stegnosis and no twist happened.Conclusion Liver transplantation is an effective treatment of final stage hepatopathy,exactitude monitoring and correct disposal,prevention and care of complication,adjunctive therapy are important conditions of liver transplantation.

三级甲等医院在具备一定条件后才能开展肝移植手术，肝移植手术是终末期肝病的有效治疗手段，其围手术期的严密监测与正确处理、并发症的防治及辅助治疗等是肝移植成功的重要条件。

Among 24 cases,no epiphyte and virus infection,no angiostegnosis,no biliary passage stegnosis and no twist happened.Conclusion Liver transplantation is an effective treatment of final stage hepatopathy,exactitude monitoring and correct disposal,prevention and care of complication,adjunctive therapy are important conditions of liver transplantation.

三级甲等医院在具备一定条件后才能开展肝移植手术，肝移植手术是终末期肝病的有效手段，其围手术期的严密监测与正确处理、并发症的防治及辅助治疗等是肝移植成功的重要条件。

Among 24 cases,no epiphyte and virus infection,no angiostegnosis,no biliary passage stegnosis and no twist happened.Conclusion Liver transplantation is an effective treatment of final stage hepatopathy,exactitude monitoring and correct disposal,prevention and care of complication,adjunctive therapy are important conditions of liver transplantation.

****甲等医院在具备一定条件后才能开展肝移植手术，肝移植手术是终末期肝病的有效治疗手段，其围手术期的严密监测与正确处理、并发症的防治及辅助治疗等是肝移植成功的重要条件。

Objective:To detect the rat model of non-alcohol fatty liver disease the effect of medical intervention Methods: The Wistar rats were fed with high fatty chow for 12 weeks to induce NAFLD.And then,these rats were fed the low fatty chow,and separately intervened by Rhizoma polygoni cuspidate,Polyene phosphatidylcholine and metformin hydrychloride or controlled by distill water for 4 weeks.The total RNA of adipose tissue was extracted and reversely translated into cDNA.

Non-alcohol fatty liver disease；Intervention；Rhizoma polygoni cuspidatei；Polyene phosphatidylcholine；Metformin hydrychloride非酒精性脂肪肝病（Non-alcohol fatty liver disease，NAFLD）是无过量饮酒史的肝实质细胞脂肪积贮和变性的病理综合症，是由于肝脏本身和各种肝外因素引起的肝脏脂肪代谢功能障碍，导致肝细胞内脂类物质蓄积过多的一种病理变化，常见原因有营养缺乏、肥胖、糖尿病、妊娠、糖皮质激素、肝炎及药物或毒物的损伤等[1]，发病机理尚未完全清楚。

Nepalensis wall polysaccharide was prepared with hot water extraction,ethanol precipitation,dialyzation,and lyophilization.the crude polysaccharide was separated by deae-cellulose chromatography and purified by sephadex g-200 chromatography.the inhibit effect of the polysaccharide on lipid peroxidation of mice liver was conducted by tba method.the model of liver-injury induced by carbon tetrachloride（ccl4was used to validate the variety of the realated ast.results onefold ingredient polysaccharide was obtained after isolated and purified.conclusion the ingredient can remarkably inhibit lipid peroxidation of rat liver and significantly reduce activity of ast.

用热水提取，乙醇沉淀提取粗多糖，再经sevag法去除蛋白，透析去除小分子物质，冷冻干燥得楮头红多糖粗品；采用deae-52纤维素柱层析和sephadex g-200凝胶柱层析进行分离纯化；用tba法考察多糖的抗脂质过氧化作用；采用ccl4急性肝损伤模型，测定其血清中ast变化。结论获得一个楮头红多糖组分。tba法表明该组分对小鼠自发性脂质过氧化具有显著的抑制作用；在保肝试验中，给药组能明显抑制ast的升高，对肝损伤有一定的保护作用。

Zeta potential was -44.23 millivolt. Viscosity was 1.83 mpa. All of which were coincided with physical desire. In addition, the tests of PHGF liposomes including irritation, hemolysis, pyrogen, anomaly toxicity and hypersensibility, proved that the preparation reached the standard of intravenous injection entirely. Taking glutamic pyruvic transaminase and malondialdehyde in mice as index, studies on pharmacodynamics after hepatic injure caused by tetrachloromethane in mice indicated that GPT level (P.001) and MDA yieldment P

以小鼠CCli急性中毒性肝损伤为模型，以动物血清中谷丙转氨酶（GP水平与肝脏中丙二醛p A烨成量为指标，进行PHGF脂质体的药效学试验，结果表明P＊＊F脂质体能显著降低GP T水平o＜0刀01）与MD A 生成量厌＜o.05）；大鼠组织形态的观察表明高剂量＊＊＊F脂质体能使肝脏 0 内皮细胞增生活跃，提高肝细胞的免疫功能，对受损肝细胞具有修复作用；同样小鼠碳廓清试验也显示PHGF脂质体较市售粉针具有更好的机体免 p 疫作用o功刀01），达到制剂设计目的，获得较好的结果。

This pattern is characterized by the combination of pro-MMP-2 and membrane type 1 (MT1)-MMP expression, which drie pericellular generation of actie MMP-2 and local degradation of normal lier matrix. In addition there is a marked increase in expression of TIMP-1 leading to a more global inhibition of degradation of fibrillar lier collagens by interstitial collagenases (MMP-1/MMP-13). These pathways play a significant role in the progression of lier fibrosis.

其降解肝正常基质，同时抑制引起肝纤维化的纤维胶原降解，这种情况的特点是前明胶酶A合成和膜型1－MMP表达，使得小叶内细胞激活MMP-2和降解当处的正常肝基质，此外血浆1型组织基质金属蛋白酶抑制剂（TIMP-1）明显升高引起广泛的抑制间隙胶原酶(MMP-1/MMP-13)对纤维肝脏胶原的降解。

A special delaminated expression was observed in the pericystic layer of hepatic hydatid cyst Collagen Ⅰ,Ⅲ and Ⅳ expression in the side of pericystic layer directed to the cyst of parasite(50 0%,37 5% and 40 0%) were lower than those in the side of pericyst...

靠近虫体侧纤维囊壁中，Ⅰ、Ⅲ和Ⅳ型胶原的表达阳性率分别为500%、375%和400%。靠近肝实质侧纤维囊壁中，Ⅰ、Ⅲ和Ⅳ型胶原的表达阳性率分别为875%、825%和850%。Ⅰ、Ⅲ、Ⅳ型胶原在两层中表达的差异均有显著意义(P01，P01，P01)。肝包虫囊肿周围人体纤维囊壁分层，Ⅰ、Ⅲ和Ⅳ型胶原与肝实质侧纤维囊壁的形成有密切关系。

The synthetical curative effects of Yang Gan Kang Ai Wan and TACE in moderate or advanced primary liver cancer are better than TACE.Yang Gan Kang Ai Wan has the effects of assistance and suppression on TACE.It could prolongate survival period,improve the survival rate,suppress or abate the damage to hemopoietic system,liver function and hepatic fibrosis caused by TACE.

养肝抗癌丸联合TACE疗法能够有效地抑制或减轻TACE疗法导致的毒副反应，保护和改善中晚期原发性肝癌患者造血功能和肝细胞功能，拮抗TACE导致的肝纤维化损害，延长患者的生存期，提高生存率和生存质量，治疗中晚期原发性肝癌的综合疗效优于TACE疗法。

In group E, which had just experienced 30-minute cold storage without rewarm ischemia, hepatic function could well be recovered in a short time during reperfusion. On the contrary, in group F、G and H, which had experienced rewarm ischemia for 15, 30 and 60 minutes respectively following 30-minute cold storage, hepatic function suffered the more severe damage with the more prolonged rewarm ischemia during reperfusion.

在对供肝复温缺血-再灌注损伤的研究中发现，供肝于再灌注期间，仅低温保存30分钟而无复温缺血的E组供肝功能于短时间内即可得到很好的恢复，但低温保存30分钟后又分别经历15、30、60分钟复温缺血的F、G、H三组供肝，其肝脏功能却遭到了明显的损伤，且复温缺血时间越长者，损伤程度越重。

She gently rebuff ed him, but agreed that they could be friends

她婉言拒绝了，但同意作为朋友相处。

If in the penal farm, you were sure to be criticized.

要是在劳改农场，你等着挨绳子吧！