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Objective To investigate the effect of matrine on proliferation and apoptosis of Hepatic Stellate Cell in vitro.

目的研究苦参碱对体外培养的肝星状细胞增殖和凋亡的影响,同时观察其对肝细胞有无毒性作用,探讨苦参碱抗肝纤维化的作用机制。

Among the combinations made up of different indices, the Cronbach's alpha coefficient of the combination made up of 'liver parenchyma≥gradeⅡ','right midclavicular subcostal' and 'portal vein diameter' was 0.6566 which was the highest, showing the strongest internal consistency.

在不同B超指标的组合中,以"肝实质Ⅱ级以上"、"肝锁骨中线肋下"和"肝门脉内径"3个指标组合的克朗巴哈α系数最大,为0.6566,具有较强的内部一致性。

CT perfusion images can visually show different traits of Hemodynamics of hepatic Benign and Malign pathology; No matter what background, various parameters of hepatic tissue around malign lesions had significant difference with far-end liver tissue, while various parameters of hepatic tissue around benign lesions had no significant difference with far-end liver tissue; Allopatric efficiency of hepatic Malign pathology distinctly went up with hepatocirrhosis background;Various parameters of hepatic Benign and Malign pathology had no significant difference and differential significance were no significant.

灌注参数图像能直观显示肝脏良、恶性占位性病变血流动力学的不同特点;无论在何种背景下,恶性病变灶周组织与远端肝组织各同种参数间有显著差异,而良性病变灶周组织与远端肝组织各同种参数间无显著差异,以上特点可以鉴别肝脏占位性病变的良、恶性;肝硬化背景下,恶性病变的发生率明显增高;正常肝组织背景下,良、恶性占位病变组织灌注参数间无显著差异,鉴别诊断意义不大。

objectiveto study the protective and therapeutic effects of the extract of retinervus luffae fructus and carapax trionyei on con a-induced hepatic fibrosis in balb/c rats.methodsthe hepatic fibrosis in rats was first induced by intravenous injection of concanavalin a, the treatment in both protective and therapeutic stage was performed by subcutaneous injection of the extract.

目的 探讨鳖甲复方中药针剂对con a在balb/c雄性小鼠中诱导肝纤维化的预防和治疗作用。方法采用con a诱导肝纤维化,造模期间及造模成功后均用复方中药针剂干预药剂组,比较组间各项血液生化指标和肝脏组织学方面的差异,以探讨针剂对肝纤维化的预防和治疗作用。

The results showed that ZBC can improve the rats mental state, diet, hair, increase their body weight,decrease remarkably ALT, AST, and GGT activity, raise ALB content and A/G, decrease the levelof serum HA, LN, PC III and IV-C, and decrease Hyp content of liver tissue, restrain mRNA expression of III collagen, relieve remarkably the inflammalion damage, fatly degeneration of the liver cells, and reduce the collagen fibre of the liver.

枳鳖胶囊可明显改善肝纤维化大鼠的精神状态、饮食、毛色泽,增加其体重;显著降低血清AST、ALT、GGT,显著升高血清ALB、A/G;降低血清HA、LN、PCⅢ、Ⅳ-C和肝组织Hyp含量;明显减轻大鼠肝细胞损害、肝脏脂肪变性和胶原纤维增生的程度;抑制Ⅲ型胶原mRNA的表达。

The thickness of bovine liver in vitro ranged from 4 to 10 cm. Ultrasound energy was continuously delivered to ablate the liver with a frequency of 1.6MHz, and spatial peak pulse average acoustic intensity of 12000 W/cm^2. The characteristics of complete coagulation necrosis and exposure time were measured after FUSC exposure, and pathological changes in treated bovine liver tissue were observed.

在超声频率为1.6MHz,声强12000W/平方公分条件下,对厚度4~10cm离体牛肝进行双面连续扫描辐照后,记录牛肝达到贯通性凝固性坏死的辐照时间,测量离体牛肝凝固性坏死性状的形状和特征,观察组织病理学的变化。

The rupture of the branches of venae hepaticae intermediae intruding beds of gallbladders is the important reason causing the bleeding on beds of gallbladders during cholecystectomize.

结论(1)突入胆囊床的肝中静脉属支破裂是引起胆囊切除时胆囊床大出血的重要原因;(2)在胆囊床由左前下向右后上方缝合肝组织是对突入胆囊床肝中静脉属支破裂出血的有效预防方法。

Objective: To compare two alternative ultrasound parameters, hepatic vein flow pattern and presence of focal hypoechoic areas within the liver hilus, as non-invasive predictors of liver steatosis in patients with chronic hepatitis C virus infection.

目的:比较两种不同的无创超声参数,即肝门内肝静脉血流模式和是否存在肝门局部低回声区,对预测慢性丙肝病毒感染患者的肝脏脂肪变性的效果。

Objective: To compare two alternative ultrasound parameters, hepatic vein flow pattern and presence of focal hypoechoic areas within the liver hilus, as non-invasive predictors of liver steatosis in patients with chronic hepatitis C virus infection.

摘要目的:,比较两种不同的无创超声参数,即肝门内肝静脉血流模式和是否存在肝门局部低回声区,对预测慢性丙肝病毒感染患者的肝脏脂肪变性的效果。

After treatment,the various stained indexes such as liver hematoxylin and eosin staining,SDHase and ATPase histochemic staining,and the conten...

调节三羧酸循环,促进脂肪酸的β氧化和肝内甘油三酯的转运是肝脂消方抗肝脂肪变性的重要作用机制。

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