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Methods Forty mice were randomly divided into 4 groups: one normal control group,mice in the other three groups were all infected each with 25 cercariae, the infected control group was fed for 10 weeks after infection, and 2 weeks after infection, the high dose PTX group was given PTX 360 mg/ for 8 weeks and the low dose PTX group was given PTX 180 mg/also for 8 weeks.

将40只小鼠随机分为4组,其中3组每只小鼠人工感染日本血吸虫尾蚴25条,1组感染后继续喂养10周,不作治疗,作为感染对照组;2组分别于感染后2周用PTX 360 mg/和180 mg/灌胃治疗8周;另1组不感染、也不接受药物治疗,与上述3组同步喂养10周,作为正常对照组。10周后将上述4组小鼠分别剖杀取肝组织,光镜观察肝组织病变;用免疫组化染色方法检测小鼠肝组织中Bcl-2、Bax的水平。

Liver or kidney aspirate examination and specific dyeing is necessary in patients suspected with hepatic amyloid degeneration.

结论对临床上高度怀疑为肝淀粉样变性的患者,作肝肾活体组织检查及特异性组织学染色,可证实为肝淀粉样变性。

While , the amylase and lipase activities in stomach were significantly higher than those in intestine and hepatopancreas. In C. asiatica adults, the protease activity was highest in midgut mucosa with lowest in stomach mucosa. The trypsin activity was highest in midgut mucosa and lowest in hindgut mucosa. While, the amylase activity was highest in hindgut mucosa with lowest in foregut mucosa, and the lipase activity in the stomach mucosa was distinctly higher than that in other digestive organ or tissues.

月鳢成鱼蛋白酶活性以中肠粘膜组织和后肠粘膜组织最高,前肠粘膜和肝胰脏次之,胃粘膜最低;胰蛋白酶活性以中肠粘膜组织和前肠粘膜最高,胃粘膜组织次之,肝胰脏小于胃粘膜,后肠粘膜组织的胰蛋白酶活性最小;淀粉酶活性以后肠粘膜组织和中肠粘膜组织最大,肝胰脏次之,胃粘膜组织和前肠粘膜组织最小;脂肪酶活性以胃粘膜组织最大,其他器官组织该酶活性均表现较小。

Results Among 13 variables associated with liver fibrosis selected by univariate analysis, age, gamma glutamyltranspeptidase, hyaluronic acid, and platelet count were indentified by multivariate logistic regression analysis as independent factors of fibrosis.

结论运用无创诊断模型评价慢性肝炎肝纤维化严重程度具有敏感、准确和可重复性,并有望在一定程度上替代肝活组织检查来监测慢性乙型肝炎肝纤维化的动态变化。

Objective To discuss the value of interventional radiology treatment for hugy pice of hepatic cancer.Methods Conventional TAI,TACE,PEI perfusion chemotherapy and multiple percutaneous transhepatic injection of anhydrous alcohol under guidance of CT were used for different cases together.The effect of therapy was observed and analyzed.

目的 探讨运用综合介入放射学方法治疗巨块型肝癌的临床疗效方法联合运用常规肝动脉灌注化疗术,肝动脉栓塞化疗术,CT定位经皮肝穿刺肿瘤内点注射无水酒精治疗巨块型肝癌,观察分析治疗效果。

Infarcts are uncommon because the liver has two blood supplies-portal venous system and hepatic arterial system.

肝梗死少见,由于肝有双重的血液供应-门静脉和肝动脉。

Local degeneration of hepatic cell were observed, after injecting LPS, the nucleus were largened and dyed strongly. Conclusion The mouse model of alcohol liver injury was successfully established by complex alcohol liquid food and LPS, and the alcohol extract of Schisandra can reduce alcohol liver injury.

酒精联合LPS建立了小鼠酒精性肝损伤模型,适用于酒精性肝损伤防治药物的研究;五味子酒精提取物具有降低酒精性肝损伤作用。

The results showed that their activities and contents were increased 4 hours after the lobus sinister was resected at the first time partial hepatectomy ...

结果表明:第 1次切除肝左叶后 4h,ACP和 AKP活性及 HSC70 /HSP6 8和 PCNA表达量均增加;第 2、3次分别切除肝中叶、右叶后,ACP活性和 PCNA含量与 AKP活性和 HSC70 /HSP6 8含量显负相关性;PCNA的表达量与部分肝切除次数成正比。

In the reforming cryopreserving method, the fetal liver tissues were permeated and equilibnzed in cryoprotectant A and B for 20 minutes, respectively, and then put into liquid nitrogen quickly after cold equilibrium at liquid nitrogen steam for 5 minutes.

改良冻存法:胎肝组织在A液、B液中分别渗透平衡20min后,在冷冻保护液B液中经液氮蒸汽冷平衡5min后迅速入液氮冻存,1周后复苏,入DMEM培养液37℃孵育1h,胶原酶消化胎肝组织,分离、收集消化后的胎肝细胞培养观察。

Sodium arsenite group and sodium arsenate group were made by 300 mg/L per day of sodium arsenite and sodium arsenate respectively. The mice were sacrificed after 10 months for liver function and pathologic examination. The expression of MMp-8, TIMP-2, Col-Ⅰ、Col-Ⅲ mRNA were detected with real time flourescence quantitative PCR. The result was controlled with 18s.

亚砷酸钠组和砷酸钠组给予普通饲料和砷溶液。10个月后处死小鼠,血清进行肝功能检测;苏木素-伊红染色部分肝组织;Trizol-酚-氯仿一步法提取小鼠肝组织总RNA,紫外分光光度法测定总RNA浓度及纯度,实时荧光定量PCR法测肝组织中MMP-8、MMP-2、Col-Ⅰ、Col-Ⅲ mRNA的表达,以18S基因作为质控。

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