肝的

Methods hepatocytes were digested by iv-collagenase and cultured with low-serum medium, induced by h2o2 after 12～16 h. various concentrations of calf liver extract were added to the primary cultured hepatocytes to observe the effect of (100～1 000) mg/l calf liver extract on the injured liver cell.

采用ⅳ型胶原酶消化法制备游离肝细胞悬液，以低血清进行肝细胞原代培养，12～16 h后用0.1 mmol/l的h2o2诱导肝细胞损伤，同时加以不同浓度的肝提取物，观察(100～1 000)mg/l的小牛肝提取物对肝细胞损伤的影响。

Liver pain, or even death in cirrhotic ascites; Paragonimiasis infected cysts, child or adult worms in human tissues and organs within the transitional, If staying in the lung, patients would cough, chest pain and other discomfort, live in the brain occur in epilepsy, hemiplegia, live mainly in the liver to the liver, liver pain, will live in the subcutaneous form transitional mass or nodule; Fasciolopsiasis worm infection can suffer from abdominal pain, diarrhea, malnutrition, etc.; Angiostrongylus cantonensis larvae in human migration, lesions in the brain, can cause severe headache, nausea, vomiting, fever and neck hard, there will be serious paralysis, lethargy, coma or even death.

感染食源性寄生虫病后可出现不同的症状或体征：华枝睾吸虫病的危害主要是肝受损，轻症者可出现胃肠道不适症状，重者常有肝肿大、肝区疼痛、肝硬变腹水甚至死亡；感染肺吸虫囊蚴后，童虫或成虫在人体组织与器官内移行，若寄居在肺里，患者会出现咳嗽、胸痛等不适感觉，寄居在脑中则出现癫痫、偏瘫等情况，寄居在肝内主要表现为肝大、肝痛，寄居在皮下则形成移行性包块或结节；感染姜片虫后可出现腹痛、腹泻、营养不良等；广州管圆线虫的幼虫在人体移行，病变集中在脑组织，可引起剧烈头痛、恶心、呕吐、发热及颈硬等，严重者会出现瘫痪、嗜睡、昏迷甚至死亡。

objective to search the factors of liver injury via the anit-induced liver injury in rats.methods male sprague-dawley rats,were divided into 4 groups,data were analyzed using a completely randmized factorial anova and linear correlation.results after anit intoxication,the necrosis of hepatic cell and neutrophil infiltration im periportal region of the liver were observed in liver setions.jinshisan can reduce the alt,the tbil.pla2 correlated positively with alt、akp and tbil.conclusion the severity of anit-induced liver injury correlated positively with the pla2.jinshisan can protect against the rat anit-induced liver injury.

目的 拟通过对α－萘异硫氰酸酯诱导大鼠肝损伤发病机理的探讨，对引起肝损伤的因素进行系统的研究。方法选择s-d大鼠，雄性，随机分4组，检测数据以平均值±标准差表示，采用方差分析，相关分析进行统计学处理。结果s-d大鼠经anit染毒后，病理切片显示肝损伤明显，汇管区有大量中性粒细胞浸润。经金石散及地塞米松治疗后，生化指标均有所下降，中药金石散优于地塞米松，血生化指标与pla2活性相关分析显示，呈正相关。结论 anit诱导的肝毒性损伤程度与肝组织匀浆pla2活力呈正相关，应用抑制剂降低pla2活力，肝损伤程度也减轻，中药金石散具有降低pla2活性，减轻肝毒性损伤。

Complete resection of lesions is the most effective way in the treatment of hepatolithiasis. The current hepatolithiasis treatment of liver resection has been the trend in hepatic segment or subsegment.

切除病灶是彻底治疗肝内胆管结石最有效的方法，目前肝内胆管结石肝切除治疗已趋向于肝段化和亚肝段化。

Results: CPCC treatment was found to effectively attenuate the degenerative changes observed in alloxan-induced animals, such as hypertrophy of liver, adhesion phenomenon between adjacent hepatic lobules, crimpling and partial necrosis of hepatocytes, inflammatory cell infiltration, vacuolation, endothelial cell injury and the nuclear damage etc.

结果：CPCC处理使四氧嘧啶处理后小鼠肝脏肿大、肝小叶粘连现象明显改善；肝指数降低；减轻肝细胞变形、肝窦淤血、炎症细胞浸润及肝细胞空泡样变、血管内皮细胞损伤，核变性程度同时CPCC能有效防止四氧嘧啶所致小鼠肝脏可溶性蛋白的变化。

Hepatocytes which expressed VEGF positively mainly distributed in fatting areas. While in later periods (8 to I 2wk), the liver tissue inflammatory was light, but diseases in hepatocytes were significant.

乙肝肝细胞的变性坏死等与肝内血管病变导致的肝血供障碍密切相关，肝内血管病变主要有血管炎症、血管阻塞、血管破坏、血管增生及肝窦狭窄、阻塞、扩张和肝窦毛细血管化。

Results Segmentalbranchesofpor-tal vein supplied correspondingly hepatic segment,and hepatic vein and its branches located between adjacenthepatic segments. Branches ofportalvein could cross the adjacenthepatic vein. The boundaries ofhepatic seg-mentswere not simple straight lines or flat planes.

结果 门静脉段级分支位于相应的肝段中，而肝静脉及其分支位于相应肝段间，肝静脉相邻各段门静脉分支可跨过肝静脉平面，肝段的分界不是简单的直线或者平面。

Result 3.1 Ultrasound result We amended the criterrion little which Hitachicommpany offered. According as the criterion, it is 1 score if liver tissues have notdifference of elasticity and there are green in the region of interest. It is 2 score ifliver tissues have not significance difference of elasticity and there are blue in greenin the region of interest. It is 3 score if liver tissues have difference of elasticity andthere are green in the region of interest of normal liver tissues and blue in the region of interest of abnormal liver tissues. After examination, we anatomised rats and gotliver tissues for pathologic checkout.

结果 3.1超声检查情况根据日立公司提供的评分标准，稍做修改，将肝组织弹性无差异，取样框内颜色均为绿色，评为1分；肝组织弹性无明显差异，取样框中颜色为绿色中微微带点蓝色，评为2分；肝组织弹性有差异，取样框内正常肝组织弹性变化为绿色，病变肝组织弹性变化为蓝色，评为3分。

After 20, 40, 60 or 90 minutes ischemia and 120 minutes reperfusion, the ratio of necrotic to no-necrotic liver were 3.9%, 13.5%, 66.4% or 82.7%, of those the percentage necrosis during reperfusion 120 minutes was 7.7%, 11.1%, 68.1% or 67.2% respectively; The liver volume of blood flow decreased to 94.7%, 85.3%, 55.9% or 43.5% of normal values in end of ischemia; Liver sinusoidal obstruction by blebs originating from the hepatocytes, fragments of sinusoidal endothelial cell damage and aggregation of blood cells was observed in group of 60, 90 minutes ischemia.

血流阻断20、 40、 60和90 min组再开放2 h，肝总坏死范围分别为3.9%、 13.5%、 66.4%和82.7%，其中肝血流开放后的肝坏死范围分别占肝总坏死范围的7.7%、 11.1%、 68.1%和67.2%；肝门静脉恒压灌流量于阻断期末分别下降5.3%、 14.7%、 44.1%和56.5%；肝血窦在阻断20、 40 min组无阻塞现象，阻断60和90 min组出现血细胞，膜浆泡和纤维束积滞，阻塞血窦面积占肝血窦总面积的50%。

objectiveto investigate the effects of yuegan capsule on ccl4 intoxicated primary cultured rat hepatocytes.methodshepatocytes injury models were induced by ccl4 in rats in vitro, and treated with yuegan capsule.structure of rat hepatocytes and effect of sdh、acpase、g 6 pase activeties and amount of hepatic glycogen were observed.

目的探讨悦肝胶囊对四氯化碳（ccl4）损伤原代培养大鼠肝细胞的保护作用。方法以ccl4诱导大鼠肝细胞损伤模型，观察悦肝胶囊对肝细胞的琥珀酸脱氢酶、酸性磷酸酶、葡萄糖-6-磷酸酶（g 6 pase）活性和糖原含量以及肝细胞形态结构的影响。

In the United States, chronic alcoholism and hepatitis C are the most common ones.

在美国，慢性酒精中毒，肝炎是最常见的。

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如果有任何问题，你可以随时联系我。