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Methods:Celiac injection of Acetamide hyposulfite 300mg/for 2days to rat was used as an animal model of hepatorenal syndrome.

给大鼠腹腔注射硫代乙酰胺300mg/,共2天,制造肝肾综合征模型。测定大鼠血中ALT/GPT、CRE、UREA、TBL、NO、内毒素、ET及ATⅡ的量。同时测定16h尿量,并计算肌酐清除率。

Diagnostic criteria for AKI are proposed based on acute alterations in serum creatinine or urine output.

AKI的诊断标准基于血清肌酐或尿排出量的急性改变。

Results: 32 patients with PNS suffered from acute oliguria or anuria,acute deterioration of renal function and rising of serum BUN and SCr, excluding secondly glomerular disease and acute tubular necrosis?

结果 :原发性肾病综合征在病情中突然发生少尿或无尿,肾功能急骤恶化,血尿素氮及肌酐上升,排除继发性肾小球疾病及其他原因引起的急性肾小管坏死、急性间质性肾炎和双肾静脉主干血栓形成,经甲基强的松龙和环磷酰胺或吗替麦考酚酯及标准疗程泼尼松、血液透析等对症治疗,32例患者肾功能均改善。

Objective To evaluate the precise、accurate and specific of enzymatic method for assaying creatinine in serum.

摘要] 目的:评价肌氨酸氧化酶法检测血清中肌酐含量的准确度、特异性和精确度。

The detection wavelength was selected at 220 nm. Results The method was linear over the concentration range of 2100 mgL^(-1) for creatine, uric acid, creatinine and hippuric acid and 100-1000 mgL^(-1) for urea. The mean recovery of the method was 97.6%-105.7%. The precisions were less than 4.2%.

结果肌酸、肌酐、尿酸和马尿酸的质量浓度在2~100 mgL^(-1)内、尿素的质量浓度在100~1 000 mgL^(-1)内线性关系良好,方法平均回收率为97.6%~105.7%,RSD均小于4.2%。

The detection wavelength was selected at 220 nm. Result The method was linear over the concentration range of 2–100 mg·L-1 for creatine, uric acid, creatinine and hippuric acid and 100 – 1000 mg·L-1 for urea.

结果 肌酸、肌酐、尿酸和马尿酸的质量浓度在2~100 mg·L-1内、尿素的质量浓度在100~1000 mg·L-1内线性关系良好,方法平均回收率为97.6%~105.7%,RSD均小于4.2%。

Objective To establish an RP-HPLC method for the simultaneous determination of 5 kinds of nonprotein-nitrogen metabolites in urine(urea, creatine, creatinine, uric acid and hippuric acid).

目的 建立RP-HPLC法同时测定尿液中尿素、肌酸、肌酐、尿酸和马尿酸5种非蛋白氮代谢产物。

aim: to establish a new reversed phase high performance liquid chromatography method for assay 4 kinds of non protein nitrogen markers of human diabetic nephro pathy, creatine, creatinine, urea and uric acid in dn patients urines.

目的:建立糖尿病患者尿液中与肾病相关的非蛋白氮代谢产物(肌酸、肌酐、尿素和尿酸)的反相高效液相色谱分离分析方法。

Key words:Creatinine;Sarcosine oxidase;Picric acid methods; Method comparison

关键词]肌酐;肌氨酸氧化酶法;苦味酸法;方法比较

Results After 24,48,72 and 96 hours of gunshot wound,the plasma level of ALT was significantly increased than that of the unwounded;AST(at 2nd,8th,24th and 48th hour),CK(at 2nd,8th and 24th hour),TG(at 24th,48th,72nd and 96th),BUN(at 2nd,8th and 24th) and DAO(at 8th,24th and 48th) were increased greatly.

1.2 检测指标所有致伤犬均于低温前、低温后即刻和伤后2,8,24,48,72和96小时抽血测丙氨酸转氨酶、天冬氨酸转氨酶、肌酸激酶、甘油三酯、尿素氮、肌酐、内毒素和二胺氧化酶含量,并同时观察生命体征的变化。

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